A proof-of-concept for biologically-based soft robotics

via University of California Davis

A robotic gripping arm that uses engineered bacteria to “taste” for a specific chemical has been developed by engineers at the University of California, Davis, and Carnegie Mellon University. The gripper is a proof-of-concept for biologically-based soft robotics.

“Our long-term vision is about building a synthetic microbiota for soft robots that can help with repair, energy generation or biosensing of the environment,” said Cheemeng Tan, assistant professor of biomedical engineering at UC Davis. The work was published June 26 in the journal Science Robotics.

Soft robotics uses lightweight, flexible and soft materials to create machines that match the versatility of living things, and soft robot designs often draw inspiration form nature. Adding actual living cells to soft robots brings scientists another step closer to creating biological-mechanical hybrid machines.

“By combining our work in flexible electronics and robotic skin with synthetic biology, we are closer to future breakthroughs like soft biohybrid robots that can adapt their abilities to sense, feel and move in response to changes in their environmental conditions,” said Carmel Majidi, a co-author and associate professor of mechanical engineering at CMU.

Biosensing with engineered bacteria

The new device uses a biosensing module based on E. coli bacteria engineered to respond to the chemical IPTG by producing a fluorescent protein. The bacterial cells reside in wells with a flexible, porous membrane that allows chemicals to enter but keeps the cells inside. This biosensing module is built into the surface of a flexible gripper on a robotic arm, so the gripper can “taste” the environment through its fingers.

When IPTG crosses the membrane into the chamber, the cells fluoresce and electronic circuits inside the module detect the light. The electrical signal travels to the gripper’s control unit, which can decide whether to pick something up or release it.

As a test, the gripper was able to check a laboratory water bath for IPTG then decide whether or not to place an object in the bath.

So far, this biohybrid bot can only taste one thing and it’s difficult to design systems that can detect changing concentrations, Tan said. Another challenge is to maintain a stable population of microbes in, or on, a robot — comparable to the microbiome or ecosystem of bacteria and fungi that live in or on our own bodies and carry out many useful functions for us.

Biohybrid systems potentially offer more flexibility than conventional robotics, he said. Bacteria could be engineered for different functions on the robot: detecting chemicals, making polymers for repairs or generating energy, for example.

Learn more: Robot Arm Tastes With Engineered Bacteria

 

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Researchers Build a Crawling Robot From Sea Slug Parts and a 3-D Printed Body

Victoria Webster A sea slug's buccal I2 muscle powers this biohybrid robot as it crawls like a sea turtle.


Victoria Webster
A sea slug’s buccal I2 muscle powers this biohybrid robot as it crawls like a sea turtle.

Swarms could one day search the depths of fresh and saltwater

Researchers at Case Western Reserve University have combined tissues from a sea slug with flexible 3-D printed components to build “biohybrid” robots that crawl like sea turtles on the beach.

A muscle from the slug’s mouth provides the movement, which is currently controlled by an external electrical field. However, future iterations of the device will include ganglia, bundles of neurons and nerves that normally conduct signals to the muscle as the slug feeds, as an organic controller.

The researchers also manipulated collagen from the slug’s skin to build an organic scaffold to be tested in new versions of the robot.

In the future, swarms of biohybrid robots could be released for such tasks as locating the source of a toxic leak in a pond that would send animals fleeing, the scientists say. Or they could search the ocean floor for a black box flight data recorder, a potentially long process that may leave current robots stilled with dead batteries.

“We’re building a living machine—a biohybrid robot that’s not completely organic—yet,” said Victoria Webster, a PhD student who is leading the research. Webster will discuss mining the sea slug for materials and constructing the hybrid, which is a little under 2 inches long, at the Living Machines conference in Edinburgh, Scotland, this week.

Webster worked with Roger Quinn, the Arthur P. Armington Professor of Engineering and director of Case Western Reserve’s Biologically Inspired Robotics Laboratory; Hillel Chiel, a biology professor who has studied the California sea slug for decades; Ozan Akkus, professor of mechanical and aerospace engineering and director of the CWRU Tissue Fabrication and Mechanobiology Lab; Umut Gurkan, head of the CWRU Biomanufacturing and Microfabrication Laboratory, undergraduate researchers Emma L. Hawley and Jill M. Patel and recent master’s graduate Katherine J. Chapin

By combining materials from the California sea slug, Aplysia californica, with three-dimensional printed parts, “we’re creating a robot that can manage different tasks than an animal or a purely manmade robot could,” Quinn said.

The researchers chose the sea slug because the animal is durable down to its cells, withstanding substantial changes in temperature, salinity and more as Pacific Ocean tides shift its environment between deep water and shallow pools. Compared to mammal and bird muscles, which require strictly controlled environments to operate, the slug’s are much more adaptable.

For the searching tasks, “we want the robots to be compliant, to interact with the environment,” Webster said. “One of the problems with traditional robotics, especially on the small scale, is that actuators—the units that provide movement—tend to be rigid.”

Muscle cells are compliant and also carry their own fuel source—nutrients in the medium around them. Because they’re soft, they’re safer for operations than nuts-and-bolts actuators and have a much higher power-to-weight ratio, Webster said.

The researchers originally tried using muscle cells but changed to using the entire I2 muscle from the mouth area, or buccal mass. “The muscle already had the optimal structure and form to provide the function and strength needed,” Chiel said.

Akkus said, “When we integrate the muscle with its natural biological structure, it’s hundreds to 1,000 times better.”

In their first robots, the buccal muscle, which naturally has two “arms,” is connected to the robots printed polymer arms and body. The robot moves when the buccal muscle contracts and releases, swinging the arms back and forth. In early testing, the bot pulled itself about 0.4 centimeters per minute.

To control movement, the scientists are turning to the animal’s own ganglia. They can use either chemical or electrical stimuli to induce the nerves to contract the muscle.

“With the ganglia, the muscle is capable of much more complex movement, compared to using a manmade control, and it’s capable of learning,” Webster said.

The team hopes to train ganglia to move the robot forward in response to one signal and backward in response to a second.

With the goal of making a completely organic robot, Akkus’ lab gelled collagen from the slug’s skin and also used electrical currents to align and compact collagen threads together, to build a lightweight, flexible, yet strong scaffold.

The team is preparing to test organic versions as well as new geometries for the body, designed to produce more efficient movement.

If completely organic robots prove workable, the researchers say, a swarm released at sea or in a pond or a remote piece of land, won’t be much of a worry if they can’t be recovered. They’re likely to be inexpensive and won’t pollute the location with metals and battery chemicals but be eaten or degrade into compost.

Learn more: Researchers Build a Crawling Robot From Sea Slug Parts and a 3-D Printed Body

 

 

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