Bioengineers from Trinity have developed a prototype patch that does the same job as crucial aspects of heart tissue.
Their patch withstands the mechanical demands and mimics the electrical signalling properties that allow our hearts to pump blood rhythmically round our bodies. Their work essentially takes us one step closer to a functional design that could mend a broken heart.
One in six men and one in seven women in the EU will suffer a heart attack at some point in their lives. Worldwide, heart disease kills more women and men – regardless of race, than any other disease.
Cardiac patches lined with heart cells can be applied surgically to restore heart tissue in patients who have had damaged tissue removed after a heart attack and to repair congenital heart defects in infants and children.
Ultimately, though, the goal is to create cell-free patches that can restore the synchronous beating of the heart cells, without impairing the heart muscle movement.
Michael Monaghan, ussher assistant professor in biomedical engineering at Trinity, and senior author on the paper, said:
“Despite some advances in the field, heart disease still places a huge burden on our healthcare systems and the life quality of patients worldwide. It affects all of us either directly or indirectly through family and friends. As a result, researchers are continuously looking to develop new treatments which can include stem cell treatments, biomaterial gel injections and assistive devices.”
“Ours is one of few studies that looks at a traditional material, and through effective design allows us to mimic the direction-dependent mechanical movement of the heart, which can be sustained repeatably. This was achieved through a novel method called ‘melt electrowriting’ and through close collaboration with the suppliers located nationally we were able to customise the process to fit our design needs.”
This work was performed in the Trinity Centre for Biomedical Engineering, based in the Trinity Biomedical Sciences Institute in collaboration with Spraybase®, a subsidiary of Avectas Ltd. It was funded by Enterprise Ireland through the Innovation Partnership Program (IPP).
Dr Gillian Hendy, director of Spraybase® is a co-author on the paper. Dr Hendy commended the team at Trinity on the work completed and advancements made on the Spraybase® Melt Electrowriting (MEW) System.
The success achieved by the team highlights the potential applications of this novel technology in the cardiac field and succinctly captures the benefits of industry and academic collaboration, through platforms such as the IPP.
The Latest Updates from Bing News & Google News
Go deeper with Bing News on:
- Longtime LI Music Teacher Left Homeless During Pandemic: Patch PMon November 20, 2020 at 11:10 pm
Also: Death penalty sought for MS-13 leader/ Boy, 4, hurt in house fire /Man stabbed: police / 1-year anniversary of baby's heart transplant ...
- Year After Baby's Life-Saving Heart Transplant: 'We Are Grateful'on November 20, 2020 at 4:15 pm
Baby Ruby received a life-saving heart transplant just before Christmas a year ago, a blood drive will be held in her honor.
- Woman with vitiligo who thought she wasn't 'attractive enough' to find love reveals how she met the man of her dreams on a dating app - and married him with her white patches ...on November 20, 2020 at 1:12 am
Tiffany Taylor, an accounting director from Pennsylvania, developed the rare skin condition vitiligo when she was just 14 years old.
- Responsible Exposure? On Average, Attackers Gain 47-Day Advantage when Exploits Predate Patches, According to Kenna Securityon November 18, 2020 at 5:20 am
New research into what happens after a new software vulnerability is discovered provides an unprecedented window into the outcomes and effectiveness of responsible vulnerability disclosure and exploit ...
- Matthew McConaughey and His Mom Address Their 'Rough Patch' on 'Red Table Talk' (Exclusive)on November 17, 2020 at 7:49 am
"[My mom] and I had a rough patch about eight years after I got famous ... I had no idea that it was too much. His heart just stopped, you know? We had a party for him, kind of a celebration of his ...
Go deeper with Google Headlines on:
Go deeper with Bing News on:
Artificial heart tissue
- Tokyo's Hello Kitty Land employs use of Israeli technology to remain openon November 20, 2020 at 6:32 pm
Leveraging artificial intelligence, signal processing and machine vision capabilities, the Binah.ai developed technology that can transform cameras into a vital signs monitoring tool.
- Artificial Organs Market by Trends, Key Players, Driver, Segmentation, Forecast to 2025on November 20, 2020 at 10:09 am
Selbyville, Delaware, The New Research Report on Global Artificial Organs Market till 2025 added by Market Study Report LLC studies the current and upcoming Market Size, Share, Demand, Growth Trend ...
- Unlock The Full Potential Of Artificial Intelligenceon November 20, 2020 at 3:05 am
The past year has been a learning experience for all of us, and collectively we’ve managed incredible things. Out of necessity, organizations have massively increased their speed of digitization and ...
- Bernard Marr: Unlock The Full Potential Of Artificial Intelligenceon November 20, 2020 at 3:02 am
combined digital surgery with artificial intelligence, in real-time surgical operations. This has led to the creation of what can be thought of as a “digital biopsy” tool that can be used to identify ...
- Why dentists should look after your heart: Rules introduced in 2008 bar routine use of antibiotics during dental appointments... even though they could reduce risk of infective ...on November 16, 2020 at 6:01 pm
New research shows that since 2009, annual cases of infective endocarditis - an infection of the heart which kills more than a third of those affected within a year - have soared by 86 per cent.