A new device can deposit drug-delivering fibers directly onto biological material
With newly developed technology, medical personnel can manufacture a bandage with drug-delivery capabilities directly onto a wound.
Electrospinning is a well-developed method for developing polymer fibers for a wide variety of applications. If biocompatible materials are used, the fibers produced can be used for biomedical applications. But electrospinning requires very high voltages, making direct deposition of the fibers onto biological material dangerous due to the shock hazard it creates.
A group of researchers at Montana Technological University has developed a portable electrospinning device with a confined electric field that can safely deposit bandages and drugs directly onto biological surfaces. The group describes the instrument — which they call the electrostatic and air driven device – in the Journal of Vacuum Science & Technology B, from AIP Publishing.
Instead of using the voltage difference between the tool and a surface to deposit the fibers, the new device uses air to spray the fibers out onto the surface, like a can of spray paint.
“In spray painting, pressurized gas forces direct particles toward a surface, creating a sort of deposited material,” said author Lane Huston, a mechanical engineering graduate student at Montana Tech. “Like spray painting, the EStAD device is used by directing its nozzle at the desired surface during operation, causing a fiber mat to be deposited onto that surface.”
By applying this spray paint-like mechanism, this device can be used to cover wounds and provide controlled drug release over time. The deposited fibers adhere to materials containing internal moisture, such as human skin.
Though use of electrospun fibers for effective drug delivery has been established in the past, previous methods have required a wound to be placed directly into the electric field path. In that configuration, the only safe option is predepositing fibers onto a surface, such as parchment paper, to collect and store for later use. The device has been tested on a porcine skin incision as well as a gloved human hand and is the first demonstration of depositing the drug-delivering fibers directly onto a wound site safely.
The authors hope this new technology will be used to aid doctors, first responders and other medical personnel with wound treatment in rural areas, where immediate medical care may not be readily available.
“The bandage material, as well as the drug used, can be chosen on demand as the situation warrants, making modular and adaptable drug delivery accessible in remote locations,” Huston said.
Though the direct deposition method is its most unique application, the researchers’ new device can also be used as a traditional tabletop electrospinning device.
Learn more: Spray painting fiber bandages onto wounds
The Latest on: Electrospinning
via Google News
The Latest on: Electrospinning
- Use A 3D Printer To Electrospin Textileson November 23, 2020 at 4:00 pm
Electrospinning is a technique in which an extruded material is accelerated from the extruder by an electrostatic charge to form an extremely thin fibre. By applying a many-kilovolt charge between ...
- Hybrisan Install New Electrospinning Production Lineon November 19, 2020 at 10:12 pm
Hybrisan, the South Wales based advanced antimicrobial specialists, have installed a new Elmarco electrospinning production line to increase ...
- New electro-spinning technology enables manufacture of medical devices on industrial scaleon November 19, 2020 at 3:59 pm
A developer of electro-spinning equipment and supplier of related services to the medical device industry, IME Medical Electrospinning (Waalre, Netherlands) announced today the launch of the MediSpin ...
- Electrospinning Drug Delivery Bandages Directly Onto Woundson November 13, 2020 at 4:01 pm
Electrospinning is a maturing manufacturing technology that is already being used in medicine to produce unusual materials with novel properties. It involves melting a polymer and extruding it ...
- Penn State Uses 3D Near-Field Electrospinning Method to Create Scaffolds for Living Tissueon November 1, 2020 at 4:00 pm
A curated collection of industry and product deep-dives. Al Siblani is a 3D printing pioneer who got his start over 19 years ago. He worked with layered object manufacturing—the paper, and laser ...
- How a charitable organization and BYU students developed a mask that could make N95s obsoleteon October 31, 2020 at 7:09 pm
Electrospinning, in this context, is a process where a dissolved polymer is pushed through a needle at high voltage, pulling the polymer out of the solution and stretching it into a tiny nanofiber.
- Global Electrospinning Machines Market Pin-Point Analysis and Growth Strategies (2021-2030) || Linari Engineering, Elmarco, Inovensoon October 27, 2020 at 8:16 pm
Oct 28, 2020 (WiredRelease via Comtex) -- The latest research report provides a complete assessment of the Global Electrospinning Machines market for the forecast year 2021-2030, which is ...
- Coaxial Electrospinning Creates Novel Contraceptive, Other Medical Deviceson October 27, 2020 at 5:01 pm
Electrospinning is a manufacturing technique that has recently been getting a lot of attention in medicine because it allows researchers to produce novel materials and devices. Essentially ...
- Hybrisan installs new electrospinning production lineon October 27, 2020 at 2:01 am
Hybrisan, a South Wales-based advanced antimicrobial specialist, has installed a new electrospinning production line to increase the production of PPE equipment, while also accelerating product ...
- Research Labson August 15, 2020 at 10:20 pm
The biofluids lab utilizes fluid and solid mechanics principles, clinical expertise and design and manufacturing to find solutions for cardiovascular flow problems. The lab scope involves both basic ...
via Bing News