New research has found that Cannnabidiol is active against Gram-positive bacteria, including those responsible for many serious infections (such as Staphyloccocus aureus and Streptococcus pneumoniae), with potency similar to that of established antibiotics such as vancomycin or daptomycin.
The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology.
Cannabidiol, the main non-psychoactive chemical compound extracted from cannabis and hemp plants, has been approved by FDA for the treatment of a form of epilepsy, and is being investigated for a number of other medical conditions, including, anxiety, pain and inflammation. While there is limited data to suggest Cannabidiol can kill bacteria, the drug has not been thoroughly investigated for its potential as an antibiotic.
Work led by Dr Mark Blaskovich at The University of Queensland’s Institute for Molecular Bioscience’s Centre for Superbug Solutions, in collaboration with Botanix Pharmaceuticals Ltd, an early stage drug discovery company investigating topical uses of synthetic cannabidiol for a range of skin conditions, found that Cannabidiol was remarkably effective at killing a wide range of Gram-positive bacteria, including bacteria that have become resistant to other antibiotics, and did not lose effectiveness after extended treatment.
“Given cannabidiol’s documented anti-inflammatory effects, existing safety data in humans, and potential for varied delivery routes, it is a promising new antibiotic worth further investigation,” said Dr. Blaskovich. “The combination of inherent antimicrobial activity and potential to reduce damage caused by the inflammatory response to infections is particularly attractive.”
Importantly, the drug retained its activity against bacteria that have become highly resistant to other common antibiotics. Under extended exposure conditions that lead to resistance against vancomycin or daptomycin, Cannabidiol did not lose effectiveness. Cannabidiol was also effective at disrupting biofilms, a physical form of bacteria growth that leads to difficult-to-treat infections.
The project was co-funded by Botanix and Innovation Connections, an Australian government grant scheme to commercialize new products, processes and services. The paper will be presented on Sunday June 23rd from 11am-1 pm at the annual conference of the American Society for Microbiology, ASM Microbe 2019, at the Moscone Convention Center in San Francisco.
Learn more: Cannabidiol is a Powerful New Antibiotic
The Latest on: Cannnabidiol
via Google News
The Latest on: Cannnabidiol
- Pro-medical marijuana group welcomes DDB approval of cannabidiolon February 20, 2020 at 3:44 am
A group in favor of medical marijuana use welcomed the Dangerous Drugs Board’s (DDB) approval of cannabidiol (CBD) for epilepsy. Philippine Cannabis Compassion Society spokesperson Donnabel Cunanan ...
- Cannabidiol Market revenue worth over USD 89 Bn by 2026: Global Market Insights, Inc.on February 20, 2020 at 3:12 am
Peru cannabidiol market is estimated to achieve more than 59.5% CAGR during 2020-2026 owing to the recent legalization of cannabis and its derivatives for therapeutic and medicinal use.
- Revive Provides Update on its Clinical Development Plan for Cannabidiol in the Treatment of Autoimmune Hepatitison February 19, 2020 at 9:50 pm
Revive Therapeutics Ltd. (“Revive” or the “Company”), a company focused on the research, development and commercialization of novel cannabinoid-based and life sciences products, is pleased to provide ...
- CBD cocktails: Eight cannabidiol-infused drinks to try in Londonon February 19, 2020 at 6:47 am
You thought you were heading out for a quiet post-work drink – but can we tempt you with some cannabis? CBD (cannabidiol) is a substance extracted from the cannabis plant, that is increasingly making ...
- Woman, 24, who suffered from painful sex and became scared of men says CBD lube has changed her lifeon February 17, 2020 at 8:20 am
A woman who found sex so painful she became terrified of men and even pretended to be gay has claimed a lubricant containing cannabidiol (CBD) has 'changed her life'. Emma Allitt, 24 ...
- CBD oil and hormones: can cannabidiol restore hormonal imbalance?on February 14, 2020 at 2:22 am
Its primary function is to control how your body releases the neurotransmitters that affect nerve impulses. The ECS could also be involved in regulating: CBD, or cannabidiol, is one of the main ...
- Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultureson February 14, 2020 at 2:13 am
GBMs eventually relapse after treatment and the average survival of GBM patients is less than two years. There is some evidence that cannabidiol (CBD) can induce cell death and increases the ...
- Legislative proposals would raise medical cannabidiol THC cap to as much as 25 gramson February 11, 2020 at 5:06 pm
DES MOINES — Legislation to increase the THC level in medical cannabis to as much as 25 grams over a 90-day period has been proposed in the Iowa House and Senate. A bill that moved out of a ...
- Legislative proposals would raise medical cannabidiol THC capon February 11, 2020 at 4:21 pm
“I’m going for the gusto,” said Zaun, who proposed a cap of 25 grams to replace the current 3 percent THC limit on medical cannabidiol. However, he conceded it’s unlikely the Legislature ...
- Iowa legislative proposals would raise medical cannabidiol THC cap to as much as 25 gramson February 11, 2020 at 1:35 pm
“I’m going for the gusto,” said Zaun, who proposed a cap of 25 grams to replace the current 3 percent THC limit on medical cannabidiol. However, he conceded it’s unlikely the Legislature and Gov. Kim ...
via Bing News