The risk of suicide among individuals with post-traumatic stress disorder (PTSD) is much higher than the general population, but identifying those individuals at greatest risk has been difficult. However, a team at Yale has discovered a biological marker linked to individuals with PTSD who are most likely to think about suicide, the researchers report May 13 in the journal Proceedings of the National Academy of Sciences.
Researchers used PET imaging to measure levels of metabotropic glutamatergic receptor 5 (mGluR5) — which has been implicated in anxiety and mood disorders — in individuals with PTSD and major depressive disorder. They found high levels of mGluR5 in the PTSD group with current suicidal thoughts. They found no such elevated levels in the PTSD group with no suicidal thoughts or in those with depression, with or without current suicidal thoughts.
There are two FDA approved treatments for PTSD, both of which are anti-depressants. It can take weeks or months to determine whether they are effective. That can be too late for those who are suicidal, note the researchers.
“If you have people who suffer from high blood pressure, you want to reduce those levels right away,” said Irina Esterlis, associate professor of psychiatry at Yale and senior author of the study. “We don’t have that option with PTSD.”
Esterlis said testing for levels of mGluR5 in people who have experienced severe trauma might help identify those at greatest risk of harming themselves and prompt psychiatric interventions. Also, researchers might investigate ways to regulate levels mGluR5 with hopes of minimizing suicide risk in PTSD patients, she said.
The Latest on: PTSD
via Google News
The Latest on: PTSD
- 'Didn't think I was going to make it': Raleigh man suffers from PTSD after two COVID-19 hospitalizationson October 7, 2020 at 4:08 pm
"Just being left in that dark room. It brings back thoughts. Not knowing if you're going to make it. You have the chills. The night sweats, you're sore, you're tossing and turning," Leroy Windley said ...
- PTSD In Teens: Helping Adolescents Cope and Deal with PTSDon October 7, 2020 at 2:34 pm
The events that cause PTSD, or Post Traumatic Stress Disorder, are as varied as the people who struggle with it, including teens.
- Mydecine Innovations Group Announces Filing of Provisional Patent for the Treatment of PTSD with Psilocybinon October 7, 2020 at 4:40 am
Mydecine Innovations Group Inc. (CSE: MYCO) (OTC: NLBIF) (FSE:0NF) ("Mydecine" or the "Company"), is pleased to announce its wholly-owned subsidiary, NeuroPharm Inc. ("NeuroPharm”), has filed a ...
- 'Brain fog' following COVID-19 recovery may indicate PTSDon October 7, 2020 at 1:10 am
A new report suggests that lingering "brain fog" and other neurological symptoms after COVID -19 recovery may be due to post-traumatic stress disorder (PTSD), an effect observed in past human ...
- Paris Jackson speaks out in support of Paris Hilton, opens up about PTSD diagnosison October 4, 2020 at 3:44 pm
Paris Jackson is sharing her story of attending a "behavior modification" boarding school in solidarity with Paris Hilton, who recently detailed the alleged abuse she suffered as a teenager at a ...
- The Descent Is a Masterful Depiction of PTSDon October 3, 2020 at 1:22 pm
Psychoanalysis explores the depths of trauma through Neil Marshall's 2005 classic.The Descent Is a Masterful Depiction of PTSDCoS Staff ...
- Paris Jackson Supports Paris Hilton, Says She Was Diagnosed with PTSD After Attending Similar Schoolon October 3, 2020 at 11:05 am
Paris Jackson is standing in solidarity with Paris Hilton after the reality star opened up about the alleged abuse she suffered while attending a Utah boarding school. Jackson, 22, shared several ...
- Chris Wallace Works Through ‘PTSD’ to Relive Chaotic Debate: Trump ‘Bears the Primary Responsibility for What Happened’on October 1, 2020 at 1:28 pm
Fox News anchor Chris Wallace is speaking out on television for the first time since the debate over which he presided on Tuesday night.
- Nurture trumps nature in determining severity of PTSD symptomson October 1, 2020 at 9:29 am
The ability to form secure attachments neutralizes the genetic risk for PTSD symptoms in veterans, new Yale research has found.
- Researchers streamline PTSD diagnosis with machine learningon September 30, 2020 at 8:04 am
Post-traumatic stress disorder (PTSD) affects eight million adults in the US, including hundreds of thousands of veterans of the conflicts in Iraq and Afghanistan. And as the COVID crisis continues to ...
via Bing News