Howard Hughes Medical Institute (HHMI)

The Howard Hughes Medical Institute (HHMI) is a United States non-profit medical research organization based in Chevy Chase, Maryland.

Using genetically engineered bacteriophages to fight infection: Viruses that can infect and kill bacteria

Scientists have used an experimental therapy that relies on bacteria-infecting viruses collected, in part, through HHMI’s SEA-PHAGES program to fight a Mycobacterium infection in a 15-year-old girl. The patient, a 15-year-old girl, had come to London’s Great Ormond Street Hospital for a double lung transplant. It was the summer of 2017, and her lungs were struggling to

Using genetically engineered bacteriophages to fight infection: Viruses that can infect and kill bacteria

New hope for neurodegenerative brain disorders

DGIST’s research Team has clarified the fundamentals of coiled toxin protein which causes neurodegenerative brain disorders A research team led by Professor Sung Bae Lee of Brain and Cognitive Sciences and Professor Daehee Hwang of New Biology (Vice-head of the Plant Age and Life Research Group, IBS) has identified the early neuropathology mechanism of structural

New hope for neurodegenerative brain disorders

Using genomics and gene editing rapidly bring groundcherries toward domestication

By combining genomics and gene editing, researchers have figured out how to rapidly bring a plant known as the groundcherry toward domestication. Strawberries, blueberries, blackberries, raspberries, and… groundcherries? A little-known fruit about the size of a marble could become agriculture’s next big berry crop. To prepare the groundcherry (Physalis pruinosa) for mainstream farming, Howard Hughes Medical Institute

Using genomics and gene editing rapidly bring groundcherries toward domestication

Easy-to-use technology that simultaneously monitors neural activity at hundreds of different sites within the brain

Neuropixels probes represent a significant advance in measurement technology and will allow for the most precise understanding yet of how large networks of nerve cells coordinate to give rise to behavior and cognition. Neuroscientists who want to follow the nervous system’s cellular conversations will soon have access to easy-to-use technology that simultaneously monitors neural activity

Easy-to-use technology that simultaneously monitors neural activity at hundreds of different sites within the brain

A process that could one day enable precise DNA surgery to correct mutations that cause human diseases

A new type of DNA editing enzyme, developed in HHMI Investigator David Liu’s lab, lets scientists directly and permanently change single base pairs of DNA from A•T to G•C. The process could one day enable precise DNA surgery to correct mutations that cause human diseases. DNA editing just got a sharp, new pencil. Researchers have

A process that could one day enable precise DNA surgery to correct mutations that cause human diseases

AI saves 3,800 years work building the most comprehensive neural maps of behavior yet created (fly)

Scientists at HHMI’s Janelia Research Campus created comprehensive brain maps linking different groups of neurons to specific behaviors, using a machine-learning program that annotated more than 225 days of videos of flies – a feat that would have taken humans some 3,800 years. A smart computer program named JAABA has helped scientists create a brain-wide

AI saves 3,800 years work building the most comprehensive neural maps of behavior yet created (fly)

IsoView Microscope helps scientists see the big picture

High-speed microscope images entire living organisms at high resolution A new microscope developed at the Howard Hughes Medical Institute’s Janelia Research Campus is giving scientists a clearer, more comprehensive view of biological processes as they unfold in living animals. The microscope produces images of entire organisms, such as a zebrafish or fruit fly embryo, with

IsoView Microscope helps scientists see the big picture

Another Milestone in Hybrid Artificial Photosynthesis

Berkeley Lab Researchers Use Solar Energy and Renewable Hydrogen to Produce Methane A team of researchers at the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) developing a bioinorganic hybrid approach to artificial photosynthesis have achieved another milestone. Having generated quite a buzz with their hybrid system of semiconducting nanowires and bacteria

Another Milestone in Hybrid Artificial Photosynthesis

The Latest Research from Howard Hughes Medical Institute (HHMI)

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Our Very Latest Posts

A new temperature-responsive smart material is 1,800 times stiffer than the original hydrogel when heated

A new material that stiffens 1,800-fold when exposed to heat could protect motorcyclists and racecar drivers during accidents. Hokkaido University researchers have developed a hydrogel that does the opposite of what polymer-based materials, like plastic bottles, normally do: their material hardens when heated and softens when cooled. Their findings, published in the journal Advanced Materials, could

A new temperature-responsive smart material is 1,800 times stiffer than the original hydrogel when heated

Developing satellites that can fix other satellites

For his latest study, professor Ou Ma engineered robots to work independently but collaboratively When satellites break, which is surprisingly often, there isn’t much you can do about them. They become expensive and dangerous flotsam, orbiting Earth for years or generations until gravity eventually draws them to a fiery death in the atmosphere. University of

Developing satellites that can fix other satellites

Predict the global spread of dengue with a new tool

Researchers at CSIRO, Australia’s national science agency, QUT and Queensland Health have developed a new tool to predict the global spread of human infectious diseases, like dengue, and track them to their source. The tool draws on travel data from the International Air Transportation Association and dengue incidence rates from the Global Health Data Exchange

Predict the global spread of dengue with a new tool

Sleep research meets machine learning and it works like a dream

Researchers at the University of Tsukuba develop a machine-learning algorithm for automatically classifying the sleep stages of lab mice. Combining two techniques, they achieve 96.6% accuracy, which may help accelerate sleep research Tsukuba, Japan – Researchers at the University of Tsukuba have created a new artificial intelligence program for automatically classifying the sleep stages of

Sleep research meets machine learning and it works like a dream

Drones show the evidence that the Greenland ice sheet is getting more unstable as it fractures

The world’s second-largest ice sheet, and the single largest contributor to global sea level rise, is potentially becoming unstable because of fractures developing in response to faster ice flow and more meltwater forming on its surface. Using custom-built drones strong enough to withstand the extreme Arctic conditions, researchers led by the University of Cambridge made

Drones show the evidence that the Greenland ice sheet is getting more unstable as it fractures

Reducing atmospheric pollutants with a new paint-on graphene-based coating for concrete

Graphene Flagship partners the University of Bologna, Politecnico di Milano, CNR, NEST, Italcementi HeidelbergCement Group, the Israel Institute of Technology, Eindhoven University of Technology, and the University of Cambridge have developed a graphene-titania photocatalyst that degrades up to 70% more atmospheric nitrogen oxides (NOx) than standard titania nanoparticles in tests on real pollutants. Atmospheric pollution

Reducing atmospheric pollutants with a new paint-on graphene-based coating for concrete

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