There are more than 290,000 people estimated to be living in the United States with a spinal cord injury. Previously, it has been shown that it is possible to restore some function to young and healthy patients within a few years of injury. Now, researchers show spinal cord stimulation can immediately restore some voluntary movement and autonomic functions such as cardiovascular, bowel, and bladder years after a paralyzing injury without any significant rehabilitation.
“This was an opportunity to use epidural stimulation, combine my background in mathematics, collaborate with people from multiple disciplines including biomedical engineering and set up a truly innovative trial,” said Dr. David Darrow, a neurosurgery resident at the University of Minnesota Medical School and a lead investigator for the E-STAND Clinical trial. He is also a senior neurosurgery resident at Hennepin Healthcare and University of Minnesota Medical Center. “We wanted to push the envelope for patients. Once we determined it worked, we moved on to knocking down other barriers to translation to patient care.”
In a study recently published in the Journal of Neurotrauma, Darrow and his colleagues implanted the first series of female patients who both suffered devastating traumatic spinal cord injury. Both patients had no lower body function whatsoever and MRIs showing very little residual spinal cord at the level of injury. The two women were five and ten years from injury and in their 5th and 6th decade of life, which is much closer to the average patient with spinal cord injury compared to the work of other investigators.
“Enabling someone to move her legs more than 10 years after being paralyzed from spinal cord injury has been one of the greatest moments of my career,” said Uzma Samadani, MD, PhD, Associate Professor in the Department of Neurosurgery University of Minnesota Medical School and Neurosurgeon with Hennepin Healthcare. “I am grateful to my colleagues for their mutual hard work during the 2 years it took to get from idea to the first operation.”
In this study, researchers expanded the inclusion guidelines of who could receive epidural stimulation.
“We believe that we are studying a population that is much closer to the general population of patients with spinal cord injury,” said Darrow. “We have opened the doors to so many more patients with traumatic spinal cord injury.”
“While we are excited for all this could mean for patients, there is still a lot of research to be done, both with this therapy and through other avenues, many of which we are studying at the University of Minnesota,” said Ann M. Parr, MD, PhD, Assistant Professor in the Department of Neurosurgery at the University of Minnesota Medical School. Dr. Parr has an active translational spinal cord injury research laboratory at the Stem Cell Institute.
This work was made possible by a grant through the Minnesota Office of Higher Education SCI/TBI Grant Program and collaboration of an interdisciplinary group spread across four institutions. The stimulation devices were a gift from Abbott (formerly St. Jude’s).
The Latest on: Spinal cord stimulation
via Google News
The Latest on: Spinal cord stimulation
- Asia Pacific Spinal Cord Stimulation Devices Market Estimated to Grow with a CAGR of 9.3%, 2019-2025 - ResearchAndMarkets.comon November 18, 2019 at 4:11 pm
The "Asia Pacific Spinal Cord Stimulation Devices Market 2019-2025)" report has been added to ResearchAndMarkets.com's offering. The Asia Pacific Spinal Cord Stimulation Devices Market is expected to ...
- Spinal-cord stimulator 'really promising': Survivor moves legs for first time since Humboldt bus crashon November 15, 2019 at 10:36 pm
They’re just sort of fancy pacemakers Over the past two years, Darrow’s research team has conducted the same type of experimental procedure, in which surgeons implant a stimulator in the spine. The ...
- Global Spinal Cord Stimulation Devices Market Expected To Witness An Imperishable Growth Over 2029on November 14, 2019 at 9:24 pm
Nov 15, 2019 (WiredRelease via COMTEX) -- The industry analysis report identifying hidden opportunities of Spinal Cord Stimulation Devices Market, which will help to expand operations in the existing ...
- The translational landscape in spinal cord injury: focus on neuroplasticity and regenerationon November 14, 2019 at 1:00 pm
Unprecedented long-distance axon regeneration, cell replacement and relay formation have been achieved using spinal cord-derived neural stem cell grafts combined with growth factors. Neuromodulation ...
- Spinal Cord Stimulation System Market 2019 : Global Industry Size, Share, Growth, Forecasts to 2026on November 13, 2019 at 9:44 pm
Nov 14, 2019 (Market Prediction via COMTEX) -- A new research report titled “Global Spinal Cord Stimulation System market” successfully exhibits the complete scenario of the global and an individual ...
- Spinal cord stimulator provides Tonawanda man pain relief without opioidson November 13, 2019 at 10:46 am
"It was just pain all the time," Marra said. "I'd wake up in pain. I'd go to bed in pain." After multiple failed back surgery, he was left with few options, until a doctor recommended a spinal cord ...
- Spinal Cord Stimulation Market Size to Worth $4,236.2 Million Forecast by 2026on November 8, 2019 at 2:52 am
Spinal Cord Stimulation Market Overview: The Global Spinal Cord Stimulation Market is expected to gain from increasing per capita income. Recently Fortune Business insights, published a report, titled ...
- FDA Approves Unique Spinal Cord Stimulation System for Chronic Painon November 8, 2019 at 1:00 am
The Omnia system has conditional full body MRI approval. The Food and Drug Administration (FDA) has approved the Senza Omnia Spinal Cord Stimulation (SCS) System (Nevro) for the treatment of chronic ...
- When a spinal cord stimulator fails, the device, the body, or the mind may be to blameon November 7, 2019 at 12:51 am
For many people who suffer chronic, debilitating pain in the lower back or limbs, the implantation of a spinal cord stimulator can be a life-changer. By delivering electrical pulses that interrupt ...
- 'It gave me my life back': Spinal cord stimulation can ease pain, but access is limitedon November 6, 2019 at 3:08 am
For some people suffering chronic, severe pain, spinal cord stimulation can be a way out of a reliance on opioids, but access to the treatment has its limits in B.C.
via Bing News