Purdue University researchers are developing a novel biomedical imaging system that combines optical and ultrasound technology to improve diagnosis of life-threatening diseases.
Photoacoustic tomography is a noninvasive technique that works by converting absorbed optical energy into acoustic signal. Pulsed light is sent into body tissue, creating a small increase in temperature that causes the tissue to expand and create an acoustic response that can be detected by an ultrasound transducer. The ultrasound data is used to visualize the tissue.
“The nice thing about photoacoustic tomography is the compositional information,” said Craig Goergen, an assistant professor in Purdue’s Weldon School of Biomedical Engineering. “It provides information about where blood and lipid are located, along with other essential information.”
The ultimate goal is to enhance the clinical care of patients.
The results of a study describing an adjustable photoacoustic probe with improved light delivery and image quality were published Tuesday (Aug. 28) in the journal Photoacoustics.
The system provides real-time compositional information of body tissue without the need for contrast agents and with better depth penetration compared with conventional optical techniques.
Photoacoustic tomography can be used to detect or monitor a myriad of diseases, including cardiovascular disease, diabetes, and cancer. Those are diseases that the Centers for Disease Control and Prevention lists as among the most common, costly, and preventable of all health problems. Heart disease and cancer each account for one in every four deaths a year in the United States, and more than 30 million Americans, or more than 9 percent of the population, have diabetes. The cost of those three diseases a year in the United States is more than $718 billion a year, according to the CDC.
“That means there will be a great need for medical imaging. Trying to diagnose these diseases at an earlier time can lead to improved patient care,” Goergen said. “We are in the process now of trying to use this enhanced imaging approach to a variety of different applications to see what it can be used for.”
Among other potential uses for photoacoustic tomography is the mapping of lipid deposition within an arterial wall that can cause other health problems, measuring cardiac tissue damage and tumor biopsies. Using photoacoustic tomography for intraoperative tumor biopsies could help surgeons make sure they remove all the cancer from a patient, Goergen said.
One of the challenges of photoacoustic tomography is improving the penetration depth and signal-to-noise ratio past optical absorbers. The researchers believe creating optical manipulation techniques to maximize photon density could provide a solution. As a result, they have created a motorized photoacoustic holder that allows users to easily maneuver the aim of the device and tune the depth where light is focused, improving the light penetration depth and signal-to-noise ratio.
A video about the acoustic tomography is available at https://bit.ly/2yJddb0. A complete list of co-authors is available in the abstract. The research has been funded by the National Institutes of Health.
The Purdue researchers are interested in talking with other companies about other possible uses for photoacoustic tomography. The researchers have a patent pending for the technology with the help of the Purdue Office of Technology Commercialization.
The Latest on: Biomedical imaging
via Google News
The Latest on: Biomedical imaging
- China self-developed full-digital PET completes multiple brain imagingon August 16, 2019 at 2:14 am
the equipment is believed to be the world's first full-digital PET exclusively developed for cerebral imaging. It was developed after 19 years of efforts by a team led by Xie Qingguo, a biomedical ...
- 3D Printing Therapeutic Proteins With A New Bioink By Texas A&M Engineering Teamon August 16, 2019 at 1:21 am
Supported by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health and the National Science Foundation, the research is in the midst of emerging ...
- New contrast agent could make MRIs saferon August 15, 2019 at 1:38 pm
Gale, Ph.D., assistant in Biomedical Engineering at MGH ... adverse way and allows rapid elimination from the body after the imaging exam. "Without a chelator of sufficient strength, the manganese ...
- The power of 4-D technology advances care for heart patientson August 15, 2019 at 5:45 am
Geddes Associate Professor of Biomedical Engineering in Purdue's College of Engineering and principal investigator for the Cardiovascular Imaging Research Laboratory. "We think it could eventually ...
- Medical Holography Market 2019 Global Analysis, Size, Growth, Leading Players, Merger, Acquisition, Opportunity, With Regional Outlook To 2023on August 12, 2019 at 4:40 pm
Oct, 2014 Zebra Imaging entered into a partnership with Zygote Media Group to develop advanced 3D biomedical models to visualize human anatomy. At Market Research Future (MRFR), we enable our ...
- Pre-Clinical Imaging System Market to Witness a Healthy Growth During 2016-2026on August 9, 2019 at 9:10 am
Valley Cottage, NY -- (SBWIRE) -- 08/09/2019 -- Imaging Science is a developing field that effects different biomedical research area, for example, oncology, neurology, cardiology, immunology and ...
- Advanced imaging technology for prostate cancer could increase a man’s chances of survivalon August 9, 2019 at 3:47 am
If you use imaging together with other techniques, you can actually better customize a treatment for a specific patient." Pingkun Yan, assistant professor of biomedical engineering, Rensselaer ...
- Improved Imaging Technique Could Increase Chances of Prostate Cancer Survivalon August 8, 2019 at 7:21 am
“Imaging has become an essential component of modern medicine,” said Pingkun Yan, assistant professor of biomedical engineering at Rensselaer Polytechnic Institute. “I believe it will become more and ...
- GE Healthcare and the Association of Medical Engineering of Kenya host more than 100 biomedical engineers for Biomedical Excellence Dayon August 8, 2019 at 6:36 am
“The Biomedical Excellence Day reinforces our commitment to support ... As a leading provider of medical imaging, monitoring, biomanufacturing, and cell and gene therapy technologies, GE Healthcare ...
- Non-invasive imaging method spots cancer at the molecular levelon August 6, 2019 at 2:21 pm
Biomedical Optics Express is OSA's principal outlet for serving the biomedical optics community with rapid, open-access, peer-reviewed papers related to optics, photonics and imaging in the life ...
via Bing News