A natural human enzyme can biodegrade graphene, scientists from the Graphene Flagship have announced.
Degradation of pristine graphene occurs in the human body when interacting with a naturally occurring enzyme found in the lung, announced Graphene Flagship partners; the French National Centre for Scientific Research (CNRS), University of Strasbourg, Karolinska Institute and University of Castilla–La Mancha (UCLM).
Graphene based products are being designed to be interfaced with the human body within the Graphene Flagship, including flexible biomedical electronic devices. If graphene is to be used for such biomedical applications, it should be biodegradable and thus be expelled from the body.
To test how graphene behaves within the body, Alberto Bianco and his team at Graphene Flagship partner CNRS, conducted several tests looking at if and how graphene was broken down with the addition of a common human enzyme. The enzyme in question, myeloperoxidase (MPO), is a peroxide enzyme released by neutrophils, cells that are responsible for the elimination of any foreign bodies or bacteria that enter the body, found in the lungs. If a foreign body or bacteria is detected inside of the body, neutrophils surround it and secrete MPO, thereby destroying the threat. Previous work by Graphene Flagship partners found MPO to successfully biodegrade graphene oxide [Small, 20151; Nanoscale, 20182]. However the structure of non-functionalized graphene was thought to be more degradation resistant. To test this, Bianco and his team looked at the effects of MPO, ex vivo, on two graphene forms; single- and few-layer.
Bianco explains, “We used two forms of graphene, single- and few-layer, prepared by two different methods in water. They were then taken and put in contact with myeloperoxidase in the presence of hydrogen peroxide. This peroxidase was able to degrade and oxidise them. This was not really expected because we thought that non functionalized graphene was more resistant than graphene oxide.”
Rajendra Kurapati, first author on the study, from Graphene Flagship partner CNRS, said, “The results emphasize that highly dispersible graphene could be degraded in the body by the action of neutrophils. This would open the new avenue for developing graphene-based materials.”
With successful ex-vivo testing, in-vivo testing is the next stage. Bengt Fadeel, Professor at Graphene Flagship partner Karolinska Institute, “Understanding whether graphene is biodegradable or not is important for biomedical and other applications of this material. The fact that cells of the immune system are capable of handling graphene is very promising.”
Prof. Maurizio Prato, leader of Work Package 4, dealing with Health and Environment impact studies, based at Graphene Flagship Partner University of Trieste, said, “The enzymatic degradation of graphene is a very important topic, because in principle, graphene dispersed in the atmosphere could produce some harm. Instead, if there are microorganisms able to degrade graphene and related materials, the persistence of these materials in our environment will be strongly decreased. These types of studies are needed. What is also needed is to investigate the nature of degradation products. Once graphene is digested by enzymes, it could produce harmful derivatives. We need to know the structure of these derivatives and study their impact on health and environment.”
Learn more: Biodegradable Graphene
The Latest on: Graphene
via Google News
The Latest on: Graphene
- ZEN Graphene Solutions Ltd. Signs Graphene Oxide Purchase Agreementon November 30, 2020 at 3:50 pm
ZEN Graphene Solutions Ltd. Signs Graphene Oxide Purchase Agreement Guelph, Ontario--(Newsfile Corp. - November 30, 2020) - (TSXV: ZEN) (OTC: ZENYF) ( or the ) is pleased to announce it has ...
- New family of quasiparticles appears in grapheneon November 30, 2020 at 9:56 am
Telltale traces Researchers at the University of Manchester in the UK have identified a new family of quasiparticles in superlattices made from graphene sandwiched between two slabs of boron nitride.
- Deflating graphene balloons act as sensors for hard-to-detect gaseson November 29, 2020 at 5:00 pm
With excellent strength, flexibility and electrical conductivity, graphene has a lot of potential in a lot of different areas, and that may extend to the detection of odorless, colorless gases.
- Graphene balloons to identify noble gaseson November 27, 2020 at 9:53 am
New research by scientists from Delft University of Technology and the University of Duisburg-Essen uses the motion of atomically thin graphene to identify noble gasses. These gasses are chemically ...
- GLOBAL GRAPHENE BATTERY MARKET FORECAST 2022-2026on November 26, 2020 at 4:56 am
Reportlinker.com announces the release of the report "GLOBAL GRAPHENE BATTERY MARKET FORECAST 2022-2026" - Batteries that use graphene as electrode material are called graphene batteries. Graphene ...
- GRPEF Stock: Why Graphene NanoChem Is Soaring 40,000% Todayon November 23, 2020 at 2:43 pm
GRPEF stock is surging higher on Monday. But what do investors need to know about Graphene NanoChem and the graphene market?
- Staying ahead of the curve with 3D curved grapheneon November 20, 2020 at 9:41 am
A team of researchers has amplified 3D graphene's electrical properties by controlling its curvature. "Our research showed the conservation and the degradation of the ultra-low dissipative transport ...
- Researchers apply nanoscale graphene 'magic' angle to acousticson November 20, 2020 at 4:17 am
Two atomically thin carbon sheets stacked on top of each other, called bilayer graphene, exhibit unique properties when one of the layers is twisted at a certain angle—a "magic" angle. The study of ...
- Graphene tractor beams could one day redirect lightning strikeson November 11, 2020 at 4:00 pm
An international research team has now demonstrated a method that could effectively control where lightning strikes, using graphene microparticles trapped in a “tractor beam.” A bolt of ...
- What Is a Graphene Field Effect Transistor (GFET)? Construction, Benefits, and Challengeson November 11, 2020 at 4:00 pm
Learn all about graphene field-effect transistors or GFETs. We'll cover their construction, as well as the benefits and challenges of designing with them. As the size and performance of silicon ...
via Bing News