Super resolution microscopy is a technique that can see beyond the diffraction of light and provides unprecedented views of cells and their interior structures and organelles.
An EPFL team has developed a technique that can perform both 3D super resolution microscopy and fast 3D phase imaging in a single instrument.
This unique 4D microscope combines a sensitivity and high time resolution of phase imaging with the specifically and high spatial resolution of fluorescence microscopy. This allows the direct visualization and Analysis of subcellular structures in living cells without labeling.
These technical advances enable high-resolution visualization of the formation of pathological alpha-synuclein aggregates in hippocampal neurons. It is hoped that it will become a regular workhorse for neuroscience and biology.
The Latest on: Super resolution microscopy
- A New Look at Messenger RNA on November 12, 2018 at 10:19 am
Scientists at the Université de Montreal (UdeM) have used super-resolution microscopy to get a new look at the three-dimensional structure of messenger RNA molecules. Their research upends how we thin... […]
- AI microscopy for everyone on November 12, 2018 at 9:15 am
Image depicts a cell with fluorescently labelled mitochondria imaged by iSIM (super resolution microscopy). The segmentation DL model creates a confidence map (middle image) from an electron ... […]
- We now know how RNA molecules are organized in cells on November 11, 2018 at 4:40 pm
In their study published in Molecular Cell, scientists at UdeM used super-resolution microscopy to investigate how the 3D organization of mRNAs changes depending on the location of these molecules in ... […]
- Bruker Introduces Light-Sheet Microscope for Imaging Optically Cleared Samples on November 5, 2018 at 4:12 am
Now, as part of Bruker Corporation, Luxendo's light-sheet microscopes join Bruker's existing portfolio of swept-field confocal, super-resolution, and multiphoton fluorescence microscope product ... […]
- Supersizing superresolution microscopy: Open-source approaches to accelerate your microscopy research on October 24, 2018 at 10:37 pm
Three high-performance, open-source approaches—NanoJ-SRRF, NanoJ-SQUIRREL, and NanoJ-Fluidics—have recently been developed to enable and enhance optical superresolution microscopy in most modern micro... […]
- Super-Resolution Microscope Market by Production, Capacity, Consumption Rate, Revenue, Gross Margin Analysis by 2025 on October 24, 2018 at 12:01 am
The Analysis of incomes, limits and benefits of Key Manufacturers including the market holdings, offers of units, income dispersion, and the measures that have been taken to overcome the issues faced. ... […]
- Super-resolution microscopy builds multicolor 3-D from 2-D on October 1, 2018 at 8:09 am
Human centrioles labelled with antibodies against two proteins (Cep152, HsSAS-6) and imaged using super-resolution microscopy. From many individual particles showing projections of the centriole compl... […]
- Global Super-Resolution Microscope Industry Sales, Revenue, Gross Margin, Market Share by Top Companies on September 28, 2018 at 5:00 pm
Global Super-Resolution Microscope Market by Manufacturers, Types, Regions and Application Research Report Forecast to 2025 (EMAILWIRE.COM, September 29, 2018 ) Global Super-Resolution Microscope Mark... […]
- Visualizing and discovering cellular structures with super-resolution microscopy on August 30, 2018 at 5:00 pm
Howard Hughes Medical Institute, Department of Chemistry and Chemical Biology, Department of Physics, Harvard University, Cambridge, MA 02138, USA. Super-resolution microscopy has overcome a long-held ... […]
- Super-resolution microscopy: Getting even closer to the limit on August 21, 2018 at 2:50 am
SOMAmer-based DNA-PAINT super-resolution microscopy enables improved spatial resolution. Upper left: Traditional diffraction-limited image of nulcear pore complex proteins on a nuclear cell membrane. ... […]
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