The worst Ebola virus disease outbreak in history ended in 2016 after infecting 28,600 people and killing about 11,300 worldwide.
The outbreak led to urgent action by medical experts across the world to combat this devastating disease; including the setting up of trials of vaccines to stop the disease taking hold.
This global commitment to develop a vaccine against the disease suggested eight options, out of a starting pool of 15 candidates, should be evaluated in clinical trials worldwide by the end of 2015.
Professor Sanjeev Krishna, of St George’s University of London’s Institute for Infection and Immunity, said: “An unprecedented Ebola outbreak showed how it is possible for academics, non-governmental organisations, industry and funders to work effectively together very quickly in times of medical crisis. The results of the trial show how a vaccine could best be used to tackle this terrible disease effectively.
“We need a system of specialists, medical experts and organisers that maintains vigilance against outbreak diseases like Ebola.
“We should continue to improve ways to make, evaluate and deliver vaccines when they are needed, often in parts of the world lacking in infrastructure for diagnosing infections and providing treatments.”
He explained that considering the persistent replication of the vaccine which is called rVSV-?GP-ZEBOV in children and adolescents, further studies investigating lower doses in this population are warranted.
The vaccine contains a non-infectious portion of a gene from the Zaire Ebola virus. The St George’s researchers worked with colleagues on a vaccine trial in Gabon.
In addition, lower vaccine doses should be considered when boosting individuals with pre-existing antibodies to Ebolavirus glycoprotein, a finding that has emerged after the vaccine was tested in a country that has experienced Ebolavirus outbreaks in the past.
The vaccine was one of two being examined as a ‘candidate’ option by the World Health Organisation to identify urgently a vaccine to combat the Ebola virus outbreak in West Africa.
The clinical trial was led by colleagues at University of Tübingen in Germany, coordinated by Professor Peter Kremsner with their partner institute CERMEL in Lambaréné, Gabon.
The Latest on: Ebola vaccine
- NewLink up 13% premarket on FDA acceptance of Ebola vaccine applicationon September 18, 2019 at 8:48 am
Thinly traded nano cap NewLink Genetics (NASDAQ:NLNK) is up 13% premarket on modest volume in response to the FDA's acceptance of licensee Merck's marketing application for Ebola vaccine V920.
- Will This Ebola Vaccine Be the Next Big Thing?on September 18, 2019 at 6:55 am
NewLink Genetics Corp. (NASDAQ: NLNK) shares jumped on Wednesday after the firm announced that the U.S. Food and Drug Administration (FDA) has accepted Merck & Co.’s (NYSE: MRK) Biologics ...
- FDA accepts NewLink's partnered BLA for ebola vaccineon September 18, 2019 at 12:19 am
NewLink Genetics (NASDAQ:NLNK) +14.6% after-hours on news that the U.S. Food and Drug Administration accepted the Biologics License Application and granted priority review for partner Merck's V920 ...
- Explosion Reported at Russian Lab Carrying Dangerous Viruses Like Ebola and Smallpoxon September 17, 2019 at 11:41 am
RELATED: 14-Year-Old Girl Fighting for Her Life After Contracting EEE, a Rare Mosquito-Borne Illness Specialists at the center are developing vaccines for swine flu, Ebola, and HIV, TASS reported.
- Russia Confirms Explosion At Ex Bioweapons Lab Storing Ebola, Smallpox And Plagueon September 17, 2019 at 9:16 am
State media also confirmed that the facility, which is “known for having developed vaccines for Ebola and hepatitis, as well as for studying epidemics and general issues surrounding immunology,” was ...
- A gas explosion ripped through a Russian lab storing deadly diseases like smallpox, anthrax, and Ebolaon September 17, 2019 at 5:58 am
A gas cylinder at a major Russian research lab known as "Vector" exploded in a sanitary inspection room and caused a fire on Monday.
- Explosion Hits Russian Virus Research Center That Houses Smallpox and Ebolaon September 17, 2019 at 2:55 am
Spread across dozens of acres, it employs thousands of workers. It is considered to be one of the world's leading epidemiological research centers, developing an Ebola vaccine earlier this year, ...
- Uhh, Part of the Facility Where Russia Stores Smallpox and Ebola Explodedon September 16, 2019 at 9:20 pm
Advertisement As the Bulletin of Atomic Scientists noted, Vector is considered one of the world’s leading epidemiological research centers (credited with developing an Ebola vaccine this year ...
- As Congo’s Ebola Outbreak Drags On, Untracked Cases Sow Confusionon September 16, 2019 at 4:12 pm
Health care workers, some of whom were not vaccinated, continue to die of Ebola. That’s mystifying, since more than 200,000 doses of vaccine have been given out. The W.H.O. said it had received only ...
- Congo arrests former health minister for alleged misuse of Ebola fundson September 16, 2019 at 2:16 pm
NIAID has helped pay for the purchase and distribution of an experimental Ebola vaccine, which now has been given to 220,000 people in the DRC. Officials contend the vaccine has helped slow the spread ...
via Google News and Bing News