For hundreds of years, Chinese calligraphers have used a plant-based ink to create beautiful messages and art. Now, one group reports in ACS Omega that this ink could noninvasively and effectively treat cancer cells that spread, or metastasize, to lymph nodes.
As cancer cells leave a tumor, they frequently make their way to lymph nodes, which are part of the immune system. In this case, the main treatment option is surgery, but this can result in complications. Photothermal therapy (PTT) is an emerging noninvasive treatment option in which nanomaterials are injected and accumulate in cancer cells. A laser heats up the nanomaterials, and this heat kills the cells. Many of these nanomaterials are expensive, difficult-to-make and toxic. However, a traditional Chinese ink called Hu-Kaiwen ink (Hu-ink) has similar properties to the nanomaterials used in PTT. For example, they are the same color, and are both carbon-based and stable in water. So Wuli Yang and colleagues wanted to see if Hu-ink could be a good alternative material for PTT.
The researchers analyzed Hu-ink and found that it consists of nanoparticles and thin layers of carbon. When Hu-ink was heated with a laser, its temperature rose by 131 degrees Fahrenheit, much higher than current nanomaterials. Under PPT conditions, the Hu-ink killed cancer cells in a laboratory dish, but under normal conditions, the ink was non-toxic. This was also the scenario observed in mice with tumors. The researchers also noted that Hu-ink could act as a probe to locate tumors and metastases because it absorbs near-infrared light, which goes through skin.
Learn more: Ancient ink for cancer treatment
The Latest on: Photothermal therapy
- Surgical Lasers Market Size: Key companies Profile, their market Share and other important parameters to succeed in CAGR of 9.41%on May 11, 2020 at 12:12 am
Surgical Lasers Market2020 Report is to present the global business data with a definite and strategic review. The ...
- Production of gold/silver doped carbon nanocomposites for effective photothermal therapy of colon canceron May 5, 2020 at 5:00 pm
These studies formed a background for the current research to prepare a gold/silver doped hybrid carbon nanocomposite utilizing a very facile yet effective agent for photothermal therapy against ...
- Gold Nanoprobes for Theranosticson May 2, 2020 at 5:00 pm
Gold nanoprobes (GNPs) are nanometer scale ... shown to function as effective contrast agents for imaging and photothermal therapy, and as drug delivery vehicles for targeted therapeutics.
- Gold Nanoparticles Use in Prostate Canceron May 1, 2020 at 6:10 am
Prostate cancer is one of the top four most common cancers globally. The increased use of testing has led to a greater number of cases requiring treatment.
- Nanomedicine Method May Allow for Targeted Cancer Therapyon April 23, 2020 at 1:20 pm
“The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal ... graphene towards the cancer therapy using a murine animal ...
- Transformable hybrid semiconducting polymer nanozyme for second near-infrared photothermal ferrotherapyon April 20, 2020 at 2:35 am
Molecular mechanism of NIR-II photothermal ferrotherapy was unveiled ... and PTT for NIR-II PA imaging-guided combination cancer therapy. To the best of our knowledge, our study not only pushes ...
- Synthetic networks with tunable responsiveness, biodegradation, and molecular recognition for precision medicine applicationson April 4, 2020 at 5:00 pm
Upon modification with functional small molecules, peptides, or proteins, these nanomaterials delivered methylene blue with environmental responsiveness, transduced visible light for photothermal ...
- photoacoustic imaging and low temperature photothermal therapy in theon February 13, 2020 at 8:44 pm
Photothermal Performance of the Ultrasmall CS-RuO2NPs To assess the photothermal performance of the ultrasmall CS-RuO2NPs, various concentrations of ultrasmall CS- RuO2NPs (from 10 to 50 μg/mL) ...
- Multimodal Imaging and Photothermal Therapy
- Photoresponsive Therapyon July 16, 2019 at 5:33 pm
Photothermal therapy (PTT) is a treatment in which plasmonic nanoparticles or nanoparticles containing light-reactive dyes are delivered to tumors either intravenously or intratumorally. Subsequent ...
via Google News and Bing News