Affordable gas sensor setup developed by Tohoku University team monitors trace levels of health-indicating chemicals, paving the way for future non-invasive studies.
Using hollow-core optical fibre as a sensitive gas cell, researchers in Japan have devised a relatively simple and affordable sensor for monitoring biomarkers in human breath at low concentrations. Trace amounts of gases exhaled through the nose and mouth offer clues to respiratory conditions such as asthma, as well as other easy-to-administer health screening opportunities.
Tohoku University scientists explained how their device works in the journal Sensors, using isoprene as an example. Isoprene is a known indicator of cholesterol synthesis and could offer valuable insights into a patient’s metabolism. Breath measurements taken from volunteers throughout the day allowed researchers to track changes in isoprene levels following activities such as exercise or eating.
Breath analysis has attracted much attention because it is non-invasive and has the potential to inform users on a range of health topics. However, detecting biomarkers present at low-concentrations often requires bulky and expensive laboratory systems. The Japanese scientists believe their sensor paves the way for a more portable and affordable solution.
Optical setup for gas analysis
Key to the success of the group’s apparatus is a 3-meter-long, hollow-core optical fibre, which is coated on the inside with a reflective film. Participants breathe into a connecting tube that guides the exhaled gases into the fibre’s core, where the contents are exposed to laser-driven ultraviolet light. A detector placed at the end of the optical path highlights any portions of the light signal that are absorbed as the ultraviolet emission passes through the gas sample. And this series of so-called ‘absorption peaks’ forms a chemical signature that reveal which molecules are present. The combination of a long beam-path and high-intensity emission enhances the measurement, so even chemicals present at parts-per-billion levels can be detected.
The Latest on: Real-time breath analysis
- Putting the brakes on analysis paralysison July 10, 2019 at 12:33 am
Social scientists have a name for this inability to make a decision when presented with too many choices: “analysis paralysis ... By updating your data strategy in real time, you can dramatically ... […]
- Hydrogen Breath Test Analyzer Market Healthy CAGR of 3.7% During the Forecast Period 2018 to 2028 - Persistence Market Researchon April 10, 2019 at 7:13 am
NEW YORK, April 10, 2019 /PRNewswire/ -- Preference for breath tests over other conventional medical ... At PMR, we unite various data streams from multi-dimensional sources. By deploying real-time ... […]
- Cannabix Technologies Provides Update on Marijuana Breathalyzer Developmenton March 23, 2019 at 5:38 pm
The detection of THC and its metabolites in human breath provides for real-time pharmacokinetic analysis. Such analysis provides a method for the identification of “recency of use” that will be ... […]
- Cannabix Technologies Completes Breath Collection Unit and Provides Updateon January 28, 2019 at 12:45 am
... for live data streaming and this data can be sent to the cloud for further analysis and storage. Currently the BCU will collect key real-time parameters of breath flow rate, total volume, relative ... […]
- Laser ‘Smells’ Diseases via Breath Analysison December 5, 2018 at 4:00 pm
The new device could be used for environmental monitoring and detecting industrial contamination, and also to diagnose disease by “smelling” a person’s breath. The device ... important molecule — in ... […]
via Google News and Bing News