The research could lead to huge economic gains in the pharmaceutical and agrichemical sectors, plus more affordable medicines for healthcare providers.
“…new iron catalysed reaction could prove to be a thousand times cheaper than an equivalent process…”
SCIENTISTS at the University of Huddersfield have developed a new chemical reaction that is catalysed using simple iron salts – an inexpensive, abundant and sustainable alternative to costlier and scarcer metals. The research could lead to huge economic gains in the pharmaceutical and agrichemical sectors, plus more affordable medicines for healthcare providers. It is described in a new article published by one of the world’s leading scientific journals.
The core reaction developed by the Huddersfield team has been patented, and research continues, with further publication in the pipeline. “Also, we are keen to establish connectivity with companies, so we can get these compounds out into industry as quickly as possible,” said project leader Joe Sweeney, who is Professor of Catalysis and Chemical Biology at the University.
His co-researchers and authors for the article that appears in the journal Nature Chemistry include fellow members of the academic staff at the University’s Department of Chemistry, plus talented research students.
Catalysis is an essential component of the chemical industry. It has been estimated that it underpins as much as 40 per cent of the world’s GDP. It is also the subject of intense academic investigation, meaning that the breakthrough by Professor Sweeney’s group is of exceptional scientific as well as industrial significance.
“Most of the catalytes that are in current use are so-called scarce metals such as rhodium, palladium, platinum or iridium,” said Professor Sweeney. “The advantage is that they are usually very active, so they can mediate reactions quicker and at a lower catalytic loading.
“But if you look at tables of abundance in the earth’s crust, these metals are all right at the bottom, so there has been a big push towards devising catalytic processes that use more sustainable catalysts, such as iron, which is probably the most abundant metal.”
The new Nature Chemistry article is a detailed description of an efficient and sustainable new iron catalyse reaction that could prove to be a thousand times cheaper than an equivalent process using scarce and costly metals. A further advantage is that iron – which plays a fundamental part in diet – is considered non-toxic.
The new process is highly accessible, said Professor Sweeney. “A key driver of organic chemistry is that it should be practical and shouldn’t require esoteric conditions. Our process is carried out using standard apparatus in a standard laboratory at room temperature. That is kind of the benchmark for organic chemistry.”
The research group has included experts from the key chemistry disciplines. An important part was played by Dr Nathan Patmore, an inorganic chemist whose collaboration helped establish the mechanism of the iron process.
Receive an email update when we add a new CATALYST article.
The Latest on: New catalysed reaction
via Google News
The Latest on: New catalysed reaction
- DrySyn Spiral Evaporator helps streamline synthetic organic methods developmenton August 16, 2019 at 7:40 am
The research activities of the Cresswell Group are focused on new reaction development, and the exploitation of novel or underutilized reactivity, catalysis, or reactive intermediates to solve ...
- An automated pipeline for the screening of diverse monoterpene synthase librarieson August 15, 2019 at 2:44 am
Recent advances in synthetic biology offer new routes to this chemical diversity through ... due to a lack of correlation between protein sequence and cyclisation reaction catalysed. Directed ...
- 2-year to 10-year yield inversion terrifies investorson August 14, 2019 at 7:45 pm
It is perhaps less important to study the link between yield curve inversion and recession than to focus on the implications of market reactions towards a perceived ... and 2-year treasury yield curve ...
- A new method for depositing manganese oxide thin-films on planar and complex nanostructured surfaceson August 13, 2019 at 8:34 am
(Nanowerk Spotlight) Manganese oxides have numerous applications in batteries, supercapacitors, microelectronics and (electro)catalysis – all of which ... grade high-school demonstration of a redox ...
- New Composite Material for Photooxidation Reactions Developed Using Dyes and Viruseson August 13, 2019 at 7:47 am
A study team from Aalto University has formulated an original strategy to develop virus-based materials for catalysis. The project ... study group from the Universidad Autonoma de Madrid, a new ...
- Dyes and viruses create new composite material for photooxidation reactionson August 12, 2019 at 7:49 am
A research team from Aalto University has developed a novel strategy to create virus-based materials for catalysis ... Dyes and viruses create new composite material for photooxidation reactions.
- Industrial Catalyst Market – Global Industry Analysis, Size, Share, Trends, Segmentation and Forecast 2019 – 2025on August 12, 2019 at 3:54 am
Catalysts are definite for one particular reaction and this is mostly so for enzymes which catalyze biological reactions ... are able to modify the microstructure and new properties are obtained of ...
- Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysison August 7, 2019 at 2:15 am
Here we report an enantioselective benzylic C(sp 3)−H bond arylation via photoredox/nickel dual catalysis. Sterically hindered chiral biimidazoline ligands are designed for this asymmetric ...
- New Artificial Catalysts Could Make Cleaner Chemicals and Fuels at Industrial Scaleon August 6, 2019 at 8:40 am
Every living organism relies on enzymes—molecules that boost up biochemical reactions vital for life ... In a research reported in the August 5 th, 2019, issue of Nature Catalysis, the scientists ...
via Bing News