The research could lead to huge economic gains in the pharmaceutical and agrichemical sectors, plus more affordable medicines for healthcare providers.
“…new iron catalysed reaction could prove to be a thousand times cheaper than an equivalent process…”
SCIENTISTS at the University of Huddersfield have developed a new chemical reaction that is catalysed using simple iron salts – an inexpensive, abundant and sustainable alternative to costlier and scarcer metals. The research could lead to huge economic gains in the pharmaceutical and agrichemical sectors, plus more affordable medicines for healthcare providers. It is described in a new article published by one of the world’s leading scientific journals.
The core reaction developed by the Huddersfield team has been patented, and research continues, with further publication in the pipeline. “Also, we are keen to establish connectivity with companies, so we can get these compounds out into industry as quickly as possible,” said project leader Joe Sweeney, who is Professor of Catalysis and Chemical Biology at the University.
His co-researchers and authors for the article that appears in the journal Nature Chemistry include fellow members of the academic staff at the University’s Department of Chemistry, plus talented research students.
Catalysis is an essential component of the chemical industry. It has been estimated that it underpins as much as 40 per cent of the world’s GDP. It is also the subject of intense academic investigation, meaning that the breakthrough by Professor Sweeney’s group is of exceptional scientific as well as industrial significance.
“Most of the catalytes that are in current use are so-called scarce metals such as rhodium, palladium, platinum or iridium,” said Professor Sweeney. “The advantage is that they are usually very active, so they can mediate reactions quicker and at a lower catalytic loading.
“But if you look at tables of abundance in the earth’s crust, these metals are all right at the bottom, so there has been a big push towards devising catalytic processes that use more sustainable catalysts, such as iron, which is probably the most abundant metal.”
The new Nature Chemistry article is a detailed description of an efficient and sustainable new iron catalyse reaction that could prove to be a thousand times cheaper than an equivalent process using scarce and costly metals. A further advantage is that iron – which plays a fundamental part in diet – is considered non-toxic.
The new process is highly accessible, said Professor Sweeney. “A key driver of organic chemistry is that it should be practical and shouldn’t require esoteric conditions. Our process is carried out using standard apparatus in a standard laboratory at room temperature. That is kind of the benchmark for organic chemistry.”
The research group has included experts from the key chemistry disciplines. An important part was played by Dr Nathan Patmore, an inorganic chemist whose collaboration helped establish the mechanism of the iron process.
Receive an email update when we add a new CATALYST article.
The Latest on: New catalysed reaction
via Google News
The Latest on: New catalysed reaction
- OAL expands steam infusion tech in Australia on February 19, 2019 at 2:29 am
and its potential in food production was catalysed by OAL with a £1m UK government funded Innovate UK project, together with the University of Lincoln and a UK food manufacturer. PPN has been selling ... […]
- Small, Selective Gas Sensors on February 18, 2019 at 9:06 am
How do you flush the old reagents off of the material to make room for new so that you can make a new measurement ... especially for a sensing approach that’s enabled by catalyzed reactions. You can t... […]
- Synergistic Approach to Asymmetric Catalysis Using Synthetic and Quantum Chemistries on February 10, 2019 at 10:18 pm
In this presentation, we will discuss our latest findings on the feasibility of rational catalyst design as applied to the Rh(I)-catalyzed Pauson-Khand reaction ... a visiting fellow at the Universit... […]
- Boosting solid state chemical reactions on February 8, 2019 at 7:24 am
Hajime Ito and their colleagues developed a new strategy for solid-state palladium-catalysed cross-coupling reactions using mechanochemistry that enables efficient solvent-free synthesis of ... […]
- Lithium promoted mesoporous manganese oxide catalyzed oxidation of allyl ethers on February 8, 2019 at 5:45 am
To determine if the observed catalysis is a result of leached active sites, the solid catalyst was separated from the reaction mixture by hot filtration ... In this paper, we have developed a new cata... […]
- Final Report Summary - SUSCATCU3 (Sustainable C-X and C-H Functionalization Catalyzed by Copper(III) Species) on May 14, 2018 at 5:00 pm
We have demonstrated that silver can engage in Ag(I)/Ag(III) redox cycles in cross-coupling reactions, which will open new avenues for designing Ag-catalyzed synthetic tools in organic synthesis. None... […]
- Do You Want to Eat This New Caffeine-Catalyzed Gel as Much as I Do? on April 18, 2018 at 12:44 pm
meaning it helped speed the chemical reaction up by pulling protons off of some of the components in order to change their structure and build the molecule. You’re telling me this isn’t making your mo... […]
- Role of metal-catalyzed oxidation reactions in the early pathogenesis of scleroderma on October 3, 2017 at 5:00 pm
Recent studies have demonstrated that the autoantigens targeted in diffuse scleroderma are unified by their enrichment in nucleolini and by their susceptibility to fragmentation in a novel metal-depen... […]
- A Rh(II)-catalyzed multicomponent reaction by trapping an α-amino enol intermediate in a traditional two-component reaction pathway on March 8, 2017 at 11:09 am
1 Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shang... […]
via Bing News