Testing for health conditions usually involves needles, X-rays and other invasive or uncomfortable measures. To make diagnostics less burdensome for patients, scientists are developing alternatives, looking for disease markers in urine — and even spit.
Now a study, appearing in ACS’ Journal of Proteome Research, demonstrates for the first time that individuals may have saliva “fingerprints.” The finding suggests that identifying changes in these baseline fingerprints could someday be a reliable way to detect disease.
In the search for non-invasive and less stress-inducing ways to detect disease, much effort has focused on urine testing. Individuals’ urine samples have specific metabolic signatures that can become altered when a person develops a health problem. But compounds in urine can also vary depending on factors such as diet and environment. Saliva has similar potential as an easy-to-access fluid that changes in response to health conditions, but could be less affected by diet and the environment. Paola Turano, Kurt Zatloukal and colleagues wanted to investigate how reliable this route might be.
The researchers sampled saliva and urine from 23 healthy volunteers multiple times a day over 10 days. The molecular signatures of saliva and urine were distinct and consistent for each participant. But profiles from spit samples changed less due to dietary variations than those from urine. Although longer-term research would be needed, this initial work on saliva fingerprints suggests that they could be useful in searching for signs of disease, say the researchers.
The Latest on: Diagnosing disease
via Google News
The Latest on: Diagnosing disease
- Quantum nanodiamonds may help detect disease earlieron November 25, 2020 at 9:54 am
The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a ...
- Scientists Are Looking Into The Eyes Of Patients To Diagnose Parkinson’s Diseaseon November 25, 2020 at 9:05 am
In recent years, scientists have been developing new diagnostic methods by looking through an easily accessible peephole to the brain: the retina of the human eye.
- Myasthenia Gravis Disease Market 2020 Business Challenges, Merger, Acquisition and New Investment, Future Growth, Revenue, Forecast to 2026on November 25, 2020 at 7:59 am
The Myasthenia Gravis Disease Market report provides an in-depth analysis of the Healthcare & Pharmaceuticals during the forecast period 2017-2026 which consists of the industry overview including the ...
- Co-founder of ‘ice-bucket challenge’ dies at 37 of Lou Gehrig’s diseaseon November 24, 2020 at 11:17 pm
Pat Quinn was diagnosed with Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, in 2013, a month after his 30th birthday, the ...
- NASCAR legend Morgan Shepherd diagnosed with Parkinson's diseaseon November 24, 2020 at 5:29 pm
NASCAR driver owner Morgan Shepherd has been diagnosed with early stage Parkinson's disease. The 79-year-old plans to return to the series as a car owner next year.
- Alnylam wins FDA approval for first drug to treat rare kidney diseaseon November 24, 2020 at 11:19 am
The biotech’s approach is based on a process called RNA interference, which works to silence disease-causing genes in the body.
- Anxiety may speed Alzheimer's disease progression, study sayson November 24, 2020 at 7:27 am
Older adults with memory problems may progress to Alzheimer's more quickly if they are also suffering from anxiety symptoms, a preliminary study suggests.
- Morgan Shepherd diagnosed with Parkinson’s diseaseon November 23, 2020 at 3:27 pm
We all have had challenges to overcome and Morgan has always wanted to be an encourager, defying his age in physical and mental ability. Morgan’s charity work with the physic ...
- Morgan Shepherd diagnosed with early stage Parkinson's diseaseon November 23, 2020 at 2:20 pm
Veteran NASCAR driver and team owner Morgan Shepherd has been diagnosed with early stage Parkinson’s disease. News of Shepherd’s diagnosis with the nervous system disorder was shared on his team’s ...
- How an Eye Exam May Improve Early Diagnosis of Parkinson Diseaseon November 23, 2020 at 12:14 pm
An eye exam paired with artificial intelligence machine learning technology may provide a novel approach to diagnose Parkinson disease in early stages.
via Bing News