The brain machine interface consists of a stent-based electrode (stentrode), which is implanted within a blood vessel next to the brain, and records the type of neural activity that has been shown in pre-clinical trials to move limbs through an exoskeleton or to control bionic limbs.
The new device is the size of a small paperclip and will be implanted in the first in-human trial at The Royal Melbourne Hospital in 2017.
The results published today in Nature Biotechnologyshow the device is capable of recording high-quality signals emitted from the brain’s motor cortex, without the need for open brain surgery.
Principal author and Neurologist at The Royal Melbourne Hospital and Research Fellow at The Florey Institute of Neurosciences and the University of Melbourne, Dr Thomas Oxley, said the stentrode was revolutionary.
“The development of the stentrode has brought together leaders in medical research from The Royal Melbourne Hospital, The University of Melbourne and the Florey Institute of Neuroscience and Mental Health. In total 39 academic scientists from 16 departments were involved in its development,” Dr Oxley said.
“We have been able to create the world’s only minimally invasive device that is implanted into a blood vessel in the brain via a simple day procedure, avoiding the need for high risk open brain surgery.
“Our vision, through this device, is to return function and mobility to patients with complete paralysis by recording brain activity and converting the acquired signals into electrical commands, which in turn would lead to movement of the limbs through a mobility assist device like an exoskeleton. In essence this a bionic spinal cord.”
Stroke and spinal cord injuries are leading causes of disability, affecting 1 in 50 people. There are 20,000 Australians with spinal cord injuries, with the typical patient a 19-year old male, and about 150,000 Australians left severely disabled after stroke.
Co-principal investigator and biomedical engineer at the University of Melbourne, Dr Nicholas Opie, said the concept was similar to an implantable cardiac pacemaker – electrical interaction with tissue using sensors inserted into a vein, but inside the brain.
“Utilising stent technology, our electrode array self-expands to stick to the inside wall of a vein, enabling us to record local brain activity. By extracting the recorded neural signals, we can use these as commands to control wheelchairs, exoskeletons, prosthetic limbs or computers,” Dr Opie said.
“In our first-in-human trial, that we anticipate will begin within two years, we are hoping to achieve direct brain control of an exoskeleton for three people with paralysis.”
“Currently, exoskeletons are controlled by manual manipulation of a joystick to switch between the various elements of walking – stand, start, stop, turn. The stentrode will be the first device that enables direct thought control of these devices”
Neurophysiologist at The Florey, Professor Clive May, said the data from the pre-clinical study highlighted that the implantation of the device was safe for long-term use.
“Through our pre-clinical study we were able to successfully record brain activity over many months. The quality of recording improved as the device was incorporated into tissue,” Professor May said.
“Our study also showed that it was safe and effective to implant the device via angiography, which is minimally invasive compared with the high risks associated with open brain surgery.
“The brain-computer interface is a revolutionary device that holds the potential to overcome paralysis, by returning mobility and independence to patients affected by various conditions.”
Professor Terry O’Brien, Head of Medicine at Departments of Medicine and Neurology, The Royal Melbourne Hospital and University of Melbourne said the development of the stentrode has been the “holy grail” for research in bionics.
“To be able to create a device that can record brainwave activity over long periods of time, without damaging the brain is an amazing development in modern medicine,” Professor O’Brien said.
“It can also be potentially used in people with a range of diseases aside from spinal cord injury, including epilepsy, Parkinsons and other neurological disorders.”
The Latest on: Brain-machine interface
via Google News
The Latest on: Brain-machine interface
- Novel nanoprobes show promise for optical monitoring of neural activityon October 18, 2019 at 12:25 pm
It could also lead to high-bandwidth brain-machine interfaces with dramatically enhanced precision and functionality. Monitoring the electrical activity of neurons is conventionally done using ...
- These new implants are helping us link our brains to computerson October 18, 2019 at 1:09 am
Cyborgs are no longer science fiction. The field of brain-machine interfaces (BMI) – which use electrodes, often implanted into the brain, to translate neuronal information into commands capable ...
- Can depression and anxiety be treated by stimulating brain signals?on October 17, 2019 at 6:18 am
Maryam Shanechi, the Andrew and Erna Viterbi Early Career Chair and assistant professor of electrical and computer engineering, is trying to do something that has never been done before: treat ...
- Electrical brain implants enable patient to have 'mind control' of motorized prosthetic armson October 15, 2019 at 12:12 pm
Most efforts to create such “brain-machine interfaces” have focused on one hemisphere of the brain with far fewer electrodes, but the Johns Hopkins team used both brain hemispheres to control two ...
- Exoskeleton Prototype Helps Quadriplegic Regain Control of His Bodyon October 8, 2019 at 8:34 am
Like this exoskeleton built by researchers in France, which uses a brain-machine interface to help quadriplegics regain control of their limbs. It seems the biggest breakthroughs with this particular ...
- More on: Brain-computer interface for tetraplegic manon October 7, 2019 at 9:35 am
He also can rotate his wrists while sitting or standing.” Progress to date was reported in the Lancet paper ‘An exoskeleton controlled by an epidural wireless brain–machine interface in a tetraplegic ...
- Exoskeleton: Mind-controlled robotic suit helped paralyzed man to walk againon October 5, 2019 at 11:18 pm
Exoskeleton Controlled by a Brain-Machine Interface YouTube/ The Lancet It may sound like a sci-fi story but new robotic suits may help people with spinal cord injury. A few days ago, in France this ...
- New brain-machine interface could offer control over wheelchairson October 2, 2019 at 5:30 pm
Georgia Tech researchers have created a new brain-machine interface (BMI) that uses a new class of nano-membrane electrode combined with flexible electronics and a new deep learning algorithm to help ...
- Maryam Shanechi designs machines to read mindson October 2, 2019 at 6:07 am
Now, Shanechi is forging into a new frontier — mind control. She’s on a mission to create brain-machine interfaces that not only eavesdrop on cells, but also stimulate them to alter mood. This mental ...
- Brain-machine interface could help paralysed peopleon September 23, 2019 at 4:23 am
Combination of flexible electrodes and artificial intelligence may offer simpler method for brain-machine interface to control wheelchairs, computers and robotic vehicles For people without the use of ...
via Bing News