A proof-of-concept, phase 2 trial by an international research team has found promising results for a myostatin antibody in treating the decline in muscle mass and power associated with aging.
“Myostatin is a natural protein produced within the body that inhibits muscle growth,” said Stuart Warden, a member of the research team who is also associate dean for research and associate professor in the School of Health and Rehabilitation Sciences at Indiana University-Purdue University Indianapolis. “It has been hypothesized for some time that inhibition of myostatin may allow muscle to grow, resulting in improved muscle mass and physical performance. The current study confirms these beliefs.”
In the study, injections of a myostatin antibody, made by Eli Lilly and Co., over a 24-week period resulted in an increase in lean (muscle) mass and improved performance on tasks requiring muscle power in patients older than 75 with low muscle strength, low muscle performance and a history of falling.
“This is the first study to show that myostatin antibody treatment improves performance on activities requiring muscle power,” Warden said. “‘Muscle power’ refers to the ability to generate muscle force quickly. During aging, it is lost more rapidly than muscle strength, contributing to disability, falls, reduced quality of life and, in some instances, death.”
“Myostatin antibody treatment improved muscle power in the elderly, as indicated by improvements in the ability to climb stairs, walk briskly and rise repetitively from a chair,” Warden said. “Treatment particularly benefited those who were most frail at baseline, a population who may not be receptive to conventional intervention such as resistance exercise.”
The Latest on: Muscle power
via Google News
The Latest on: Muscle power
- China and India are flexing their military muscle near a disputed border regionon June 27, 2020 at 10:15 am
Chinese forces have held live-fire drills in Tibet while India has deployed battle tanks close to the conflict zone.
- Yes, You Can Exercise Outdoors and Build as Much Muscle as You Would in the Gymon June 24, 2020 at 2:53 am
Nature’s lack of barbells means that maintaining your muscle is no walk in the park: you have to tinker your workouts at the grass roots to retain results. First, rather than dragging your dumbbells ...
- Strength training can help mature adults regain muscle mass, mobility and poweron June 17, 2020 at 11:37 am
Men and women can regain some of that lost muscle mass and, more importantly, stay strong enough to enjoy youthful activities well into their winter years, experts say. The key is strength training.
- Limpet sticking power down to mucus, not muscleon June 16, 2020 at 10:38 pm
Limpets -- those coin-sized, suction-cup critters with conical caps -- have had the experts fooled all along. "If you managed to convince a limpet like that to attach to your ceiling, it could ...
- Cowboy 3: the iPhone of the e-bike world improveson June 3, 2020 at 11:56 pm
But does it have to be done with pure muscle power? No, thanks to electric motors in the front or rear wheel, e-bikes are becoming increasingly comfortable. Besides VanMoof, Cowboy is probably one ...
- Fuel Up, Slim Down, and Build Massive Muscle With the New Men’s Health Strength Dieton May 19, 2020 at 2:23 pm
For people who are serious about getting in shape and building muscle, that last word is ... Kita Paul is the Food & Nutrition Editor of Men’s Health. This content is created and maintained ...
- How to Add Dynamic Plyometric Moves to Your Home Workouton May 18, 2020 at 5:06 am
Enter plyometrics: exercises that involve repeated, rapid stretching and contracting of muscles (as in jumping and rebounding) to increase muscle power—think jump squats and explosive clap push-ups.
- How to create a 'mini UBS', Grounds styleon May 18, 2020 at 4:35 am
New to Grounds' world is his impending partnership with Hamish Douglass' Magellan Financial Group, which is expected to provide some of the capital muscle power required to get started.
- You don't need muscle power to hit sixes: Rohit Sharmaon November 8, 2019 at 7:22 pm
You do not need muscle power to score big sixes, it is about a combination of power and timing," Sharma told Chahal. "From the team point of view, it was important to start in a good manner.
- 76 Eccentric Exercises For Achilles Tendinopathy Do Not Fully Resolve Plantarflexor Muscle Power Deficitson August 11, 2018 at 5:48 am
This data showed that the Soleus is responsible for the majority of the observed power deficits. Aim -Determine how an eccentric regime alters Plantarflexor muscle power. Method 24 runners with AT ...
via Bing News