Fifty chemicals the public are exposed to on a daily basis may trigger cancer when combined, according to new research.
A global taskforce of 174 scientists from leading research centres across 28 countries studied the link between mixtures of commonly encountered chemicals and the development of cancer. The study selected 85 chemicals not considered carcinogenic to humans and found 50 supported key cancer-related mechanisms at exposures found in the environment today.
Longstanding concerns about the combined and additive effects of everyday chemicals prompted the organisation Getting To Know Cancer led by Lowe Leroy from Halifax Nova Scotia, to put the team together – pitching what is known about mixtures against the full spectrum of cancer biology for the first time.
Cancer Biologist Dr Hemad Yasaei from Brunel University London contributed his knowledge regarding genes and molecular changes during cancer development. He said: “This research backs up the idea that chemicals not considered harmful by themselves are combining and accumulating in our bodies to trigger cancer and might lie behind the global cancer epidemic we are witnessing. We urgently need to focus more resources to research the effect of low dose exposure to mixtures of chemicals in the food we eat, air we breathe and water we drink.”
Professor Andrew Ward from the Department of Biology and Biochemistry at the University of Bath, who contributed in the area of cancer epigenetics and the environment, said: “A review on this scale, looking at environmental chemicals from the perspective of all the major hallmarks of cancer, is unprecedented”.
Professor Francis Martin from Lancaster University, who contributed to an examination of how such typical environmental exposures influence dysfunctional metabolism in cancer, endorsed this view.
He said: “Despite a rising incidence of many cancers, far too little research has been invested into examining the pivotal role of environmental causative agents. This worldwide team of researchers refocuses our attention on this under-researched area.”
In light of the compelling evidence the taskforce is calling for an increased emphasis on and support for research into low dose exposures to mixtures of environmental chemicals. Current research estimates chemicals could be responsible for as many as one in five cancers. With the human population routinely exposed to thousands of chemicals, the effects need to be better understood to reduce the incidence of cancer globally.
The Latest on: Cancer-causing chemical combinations
via Google News
The Latest on: Cancer-causing chemical combinations
- The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repairon May 26, 2020 at 2:10 am
BRD-containing proteins are frequently dysregulated in cancer, and many cancer-causing mutations have ... treatment with olaparib or I-BRD9, the combination of I-BRD9 and olaparib resulted in ...
- Aluminum may affect lead levels in drinking wateron May 18, 2020 at 4:07 pm
Until recently, researchers have not inspected the interplay between three common chemicals found in drinking ... aluminum and a combination of the two, affected a strip of lead in a jar of ...
- Cancerous Agents, Air Pollutants in Nanotube Byproductson May 10, 2020 at 5:00 pm
Study co-author Desirée Plata and colleagues revealed the results of their research at the national meeting of the American Chemical Society ... even in areas considered unrelated to the eyes. The ...
- Zenith Epigenetics: ZEN-3694: Resistance is Futileon May 4, 2020 at 7:10 am
After several years advancing this process, Zenith identified a promising candidate and initiated both a single agent and combination ... to drive expression of cancer causing genes also known ...
- MN Senate Passes Bill Banning Toxic Chemical TCE, House To Vote Next Weekon May 2, 2020 at 7:04 pm
TCE became a household name after the manufacturing plant, Water Gremlin, released elevated and unsafe levels of the cancer-causing chemical into the air in White Bear Township for more than 15 years.
- Chemicals in Tobacco Products and Your Healthon April 30, 2020 at 5:00 pm
You probably know that cigarettes contain chemicals—a mix of over 7,000 ... Henningfield JE. Combination nicotine replacement therapy for smoking cessation: rationale, efficacy and tolerability.
- Minnesota Senate OK’s Ban On Toxic Chemical TCE, House To Vote Nexton April 30, 2020 at 2:10 pm
The move to ban TCE, or trichloroethylene, began after a manufacturing plant released elevated levels of the cancer-causing chemical for more than 15 years. People living near Water Gremlin in ...
- A milder hair dye based on synthetic melaninon April 29, 2020 at 12:52 pm
However, frequent coloring, whether done at a salon or at home, can damage hair and might pose health risks from potentially cancer-causing ... "A milder hair dye based on synthetic melanin." ...
- Everyone Wants to Use Clean Beauty Products, But Does Anyone Know What "Clean" Really Means?on April 22, 2020 at 1:30 pm
But it’s hard to do with so many endocrine-disrupting chemicals (EDCs ... Some research has shown concern that retinol might be cancer-causing when exposed to sunlight — which is why experts ...
via Bing News