Genetic engineering allows biomass-degrading bacterium to make fuel in a single process
The conventional strategy for producing ethanol from plant biomass requires costly pretreatment and enzyme-driven reactions. Refining another strategy known as consolidated bioprocessing (CPB) could reduce costs. In second-generation CPB, a microorganism splits of water and ferments the products to ethanol, reducing the cost. Now, scientists engineered a strain of a CBP bacterium calledCaldicellulosiruptor bescii that efficiently breaks down biomass without pretreatment. The microbe produces ethanol, demonstrating the successful conversion of switchgrass cellulosic biomass.
Direct conversion of biomass to ethanol without pretreatment represents a new paradigm for CPB, offering the potential for carbon-neutral, cost-effective, and sustainable biofuel production.
Producing ethanol from plant biomass typically requires three major steps: physicochemical pretreatment, enzymatic breakdown of biomass into its constituent sugars, and fermentation. Pretreatment and enzymatic hydrolysis are costly steps in the process. CBP could reduce costs. In CBP, unpretreated cellulosic biomass is converted to a biofuel in a single process by a microbe that breaks down the biomass and ferments the resulting sugars.Caldicellulosiruptor bescii had been shown to ferment untreated switchgrass, but it lacked the genes to make ethanol.
The Latest on: Consolidated Bioprocessing
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The Latest on: Consolidated Bioprocessing
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- Company planning Michigan biofuel plant announces cellulosic ethanol breakthroughon April 4, 2019 at 1:50 am
Mascoma Corp., which plans a $250 million plant to make cellulosic ethanol in the Upper Peninsula, announced Thursday it has made "major research advances" that will allow it to mass-produce the ...
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- Mascoma's technology surpasses 1 billion gallonson December 12, 2013 at 12:27 pm
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- Mascoma Adds Two Industry Experts to Board of Directorson November 6, 2013 at 1:02 am
Using its proprietary consolidated bioprocessing, or CBP, technology platform, Mascoma has developed bioengineered yeasts and other microorganisms to reduce costs and improve yields in the production ...
- Qteros CEO to Speak at Lazard Capital Markets Alternative Energy Investor Summiton May 31, 2011 at 5:03 am
May 31, 2011 /PRNewswire-USNewswire/ -- Qteros, Inc., the developer of a unique and highly efficient Consolidated Bioprocessing ... will be speaking at the Lazard Capital Markets Alternative Energy ...
- ORNL team converts cellulose into isobutanolon March 14, 2011 at 5:00 pm
“In nature, no microorganisms have been identified that posses all of the characteristics necessary for the ideal consolidated bioprocessing strain, so we knew we had to genetically engineer a strain ...
- Transgenic Microbe Converts Cellulose to Isobutanol Fuelon March 9, 2011 at 7:34 am
Isobutanol can be burned in regular car engines with a heat value higher than ethanol and similar to gasoline. Using consolidated bioprocessing, a team led by James Liao of the University of ...
- Mascoma, Frontier Renewable Resources and Valero Ink Deal to Develop Commercial Cellulosic Ethanol Biorefineryon January 12, 2011 at 4:00 pm
“The culmination of Mascoma’s leading Consolidated Bioprocessing (CBP) technology, coupled with Longyear’s expertise in supplying the raw materials, is the perfect compliment for a leading oil company ...
- Qteros Management to Present at Upcoming Industry and Scientific Conferenceson September 27, 2010 at 7:00 am
Working closely with its strategic partners, Qteros expects to rapidly scale its highly efficient, lowest-cost Consolidated Bioprocessing (CBP) platform for converting non-food biomass into biofuels.
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