A team of researchers, led by Samuel K. Sia, associate professor of biomedical engineering at Columbia Engineering, has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three infectious disease markers from a finger prick of blood in just 15 minutes.
The device replicates, for the first time, all mechanical, optical, and electronic functions of a lab-based blood test. Specifically, it performs an enzyme-linked immunosorbent assay (ELISA) without requiring any stored energy: all necessary power is drawn from the smartphone. It performs a triplexed immunoassay not currently available in a single test format: HIV antibody, treponemal-specific antibody for syphilis, and non-treponemal antibody for active syphilis infection.
Sia’s innovative accessory or dongle, a small device that easily connects to a smartphone or computer, was recently piloted by health care workers in Rwanda who tested whole blood obtained via a finger prick from 96 patients who were enrolling into prevention-of-mother-to-child-transmission clinics or voluntary counseling and testing centers. The work is published February 4 in Science Translational Medicine. Sia collaborated with researchers from Columbia’s Mailman School of Public Health; the Institute of HIV Disease Prevention and Control, Rwanda Biomedical Center; Department of Pathology and Cell Biology, Columbia University Medical Center; Centers for Disease Control and Prevention—Laboratory Reference and Research Branch, Atlanta; and OPKO Diagnostics.
“Our work shows that a full laboratory-quality immunoassay can be run on a smartphone accessory,” says Sia. “Coupling microfluidics with recent advances in consumer electronics can make certain lab-based diagnostics accessible to almost any population with access to smartphones. This kind of capability can transform how health care services are delivered around the world.”
The Latest on: Smartphone diagnosis
via Google News
The Latest on: Smartphone diagnosis
- UCLA, Apple to Use mHealth, Telehealth Tools to Tackle Depressionon August 7, 2020 at 8:05 am
UCLA and Apple are partnering on a three-year study that will use mHealth and telehealth tools to tackle the root causes of depression.
- Digital Biomarkers and Biomarkers Market 2020 Global Analysis, Opportunities And Forecast to 2025on August 6, 2020 at 6:16 pm
The Global digital biomarkers and biomarkers market will show a tremendous CAGR in the forecast period from 2020-2027. Due to the advancing technology like cloud, IoT, and the ado ...
- 40 Under 40 2020: John Gray, Perkins Coie LLPon August 6, 2020 at 12:54 pm
Besides your smartphone, what’s the best tech invention ... was diagnosed with leukemia when she was two. Shortly after the diagnosis, another parent reached out to me through an organization ...
- Covidwise, the pandemic app from Apple and Google, to roll out in Virginiaon August 5, 2020 at 2:29 pm
The technology arrives nearly four months after Apple and Google partnered to create the software for public health agencies.
- Virginia first to roll out coronavirus smartphone app created by Apple, Googleon August 5, 2020 at 9:31 am
Virginia has rolled out a smartphone app to automatically notify people if they might have been exposed to the coronavirus, becoming the first U.S. state to use new pandemic technology created by ...
- India: Man sells cow to buy smartphone for children's online classes amidst the coronavirus pandemic, actor Sonu Sood vows to help himon August 4, 2020 at 5:00 pm
Having no smartphone or an internet connection ... India joins grim COVID-19 club Amitabh Bachchan COVID-19 diagnosis: Fans pray for the actor The family lives in a cowshed at the Gummer village ...
- Canadians can now download new COVID-19 exposure-alert smartphone appon July 31, 2020 at 10:09 am
Canadians can now begin downloading a voluntary smartphone app meant to warn users they’ve been near someone who tests positive for COVID-19.Prime Minister Justin Trudeau says ...
- Canadians can now download new COVID-19 exposure-alert smartphone appon July 31, 2020 at 1:38 am
OTTAWA — Canadians can now begin downloading a voluntary smartphone app meant to warn ... to patients who receive a positive COVID-19 diagnosis. Those in other provinces can still download ...
- Landmark Randomized Controlled Trial Demonstrates Efficacy of Big Health's Daylight Digital Therapeutic in Improving Anxietyon July 29, 2020 at 3:06 am
Study Conducted in Collaboration with the University of Oxford, Sleep Circadian Neuroscience Institute The University of Oxford's Sleep Circadian Neuroscience Institute, and Big Health, the global ...
via Bing News