In a remarkable new advance against the virus that causes AIDS, scientists from The Scripps Research Institute (TSRI) have announced the creation of a novel drug candidate that is so potent and universally effective, it might work as part of an unconventional vaccine.
The research, which involved scientists from more than a dozen research institutions, was published February 18 online ahead of print by the prestigious journal Nature.
The study shows that the new drug candidate blocks every strain of HIV-1, HIV-2 and SIV (simian immunodeficiency virus) that has been isolated from humans or rhesus macaques, including the hardest-to-stop variants. It also protects against much-higher doses of virus than occur in most human transmission and does so for at least eight months after injection.
“Our compound is the broadest and most potent entry inhibitor described so far,” said Michael Farzan, a professor on TSRI’s Florida campus who led the effort. “Unlike antibodies, which fail to neutralize a large fraction of HIV-1 strains, our protein has been effective against all strains tested, raising the possibility it could offer an effective HIV vaccine alternative.”
The Latest on: HIV/AIDS Vaccine
via Google News
The Latest on: HIV/AIDS Vaccine
- Health Canada Clears CytoDyn to File its BLA for Leronlimab as One Injection per Week for Combination HIV Therapyon November 16, 2020 at 3:18 am
Health Canada’s clearance for the BLA filing includes a treatment regimen of one injection per week of 350 mg of the Company’s product leronlimab, as contrasted to the dosage used in the Phase 3 ...
- Expert Warns Cold Chain Infrastructure Overhaul Needed For Covid-19 Vaccine Rollouton November 15, 2020 at 11:00 am
Lenias Hwenda, an immunologist and international health expert from Zimbabwe has warned the cold-chain logistics of distributing an RNA vaccine for Covid-19 are going to be challenging for most ...
- Covid changes "up to 100 times less than HIV": good news for vaccine developmenton November 14, 2020 at 10:17 am
"The virus mutates up to a hundred times less than HIV, this increases the hope of developing effective vaccines", announced Maria Rosaria Capobianchi, professor of molecular biology at the head of ...
- EXCLUSIVE: Bay Area residents get injected for AstraZeneca's phase 3 COVID-19 vaccine trialon November 13, 2020 at 11:37 pm
SAN FRANCISCO (KGO) -- Pfizer and Moderna's COVID-19 vaccines have made big headlines this week, but there's another vaccine in phase 3 trials that also shows a lot of promise - the Oxford AstraZeneca ...
- Scientists: COVID-19 vaccine expected to have flu-like side effectson November 13, 2020 at 11:11 am
The COVID-19 vaccine is slowly making progress toward becoming available, but experts say the side effects may pose a problem with getting everyone on board with taking it.
- Long-Lasting Shot Is More Effective at Preventing HIV in Women Than Daily Pills: New Studyon November 11, 2020 at 12:35 pm
A clinical trial showed that fewer participants contracted HIV after being injected with the drug cabotegravir than those who took a daily dose of Truvada ...
- Protecting Women Against HIV Just Got 9 Times Easieron November 11, 2020 at 9:30 am
A single injection of a drug called cabotegravir given every two months has been shown to be more effective than a daily oral dose of Truvada.
- Developing effective vaccines against SARS-CoV-2 and HIVon November 11, 2020 at 7:22 am
Researchers led by Raghavan Varadarajan, professor at the Molecular Biophysics Unit, Indian Institute of Science (IISc), are working toward developing effective vaccine strategies against two viruses: ...
- Long Lasting HIV Drugs Hold Lessons For Us Allon November 10, 2020 at 11:43 am
The successful results from a clinical trial of a new, long-acting HIV prevention drug are not just a critical milestone for those working on HIV/AIDS, but also for researchers working on other deadly ...
- Injection prevents women from contracting HIV, study findson November 9, 2020 at 3:47 pm
Results so far suggest injectable cabotegravir may be 89 percent more effective than pills at preventing HIV infection.
via Bing News