In one of the most comprehensive laboratory studies of its kind, Rice University scientists traced the uptake and accumulation of quantum dot nanoparticles from water to plant roots, plant leaves and leaf-eating caterpillars.
The study, one of the first to examine how nanoparticles move through human-relevant food chains, found that nanoparticle accumulation in both plants and animals varied significantly depending upon the type of surface coating applied to the particles. The research is available online in the American Chemical Society’s journal Environmental Science & Technology.
“With industrial use of nanoparticles on the rise, there are increasing questions about how they move through the environment and whether they may accumulate in high levels in plants and animals that people eat,” said study co-author Janet Braam, professor and chair of the Department of BioSciences at Rice.
Braam and colleagues studied the uptake of fluorescent quantum dots by Arabidopsis thaliana, an oft-studied plant species that is a relative of mustard, broccoli and kale. In particular, the team looked at how various surface coatings affected how quantum dots moved from roots to leaves as well as how the particles accumulated in leaves. The team also studied how quantum dots behaved when caterpillars called cabbage loopers (Trichoplusia ni) fed upon plant leaves containing quantum dots.
“The impact of nanoparticle uptake on plants themselves and on the herbivores that feed upon them is an open question,” said study first author Yeonjong Koo, a postdoctoral research associate in Braam’s lab. “Very little work has been done in this area, especially in terrestrial plants, which are the cornerstone of human food webs.”
Some toxins, like mercury and DDT, tend to accumulate in higher concentrations as they move up the food chain from plants to animals. It is unknown whether nanoparticles may also be subject to this process, known as biomagnification.
The Latest on: Nanoparticle accumulation
via Google News
The Latest on: Nanoparticle accumulation
- Systemically-delivered biodegradable PLGA alters gut microbiota and induces transcriptomic reprogramming in the liver in an obesity mouse modelon August 14, 2020 at 2:05 am
Biodegradable materials, including the widely used poly (lactic-co-glycolic acid) (PLGA) nanoparticles contained in slow-release drug formulations, scaffolds and implants, are ubiquitous in modern ...
- Coffee stains inspire optimal printing technique for electronicson August 12, 2020 at 11:18 pm
Coffee rings form because the liquid evaporates quicker at the edges, causing an accumulation of solid particles that ... Researchers say their ink formulations can also print pure nanoparticles and ...
- Stimulus-responsive Macromolecules and Nanoparticles for Cancer Drug Deliveryon August 12, 2020 at 5:00 pm
Once macromolecules or nanoparticles have accumulated in the ... uptake as well as intracellular drug release and subcellular accumulation. Localized Presentation of Bioactive Molecules in ...
- Coffee stains inspire optimal printing technique for electronicson August 11, 2020 at 5:00 pm
Coffee rings form because the liquid evaporates quicker at the edges, causing an accumulation of solid ... ink formulations can also print pure nanoparticles and organic molecules.This variety ...
- Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast canceron August 8, 2020 at 5:00 pm
Yet, relatively little analysis of nanoparticle fate and intratumor accumulation across biological models and immune cell or tumor compartments has been completed, particularly with histology or flow ...
- Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T H 17 responseson August 8, 2020 at 3:26 pm
This was accompanied by a nearly exclusive priming and accumulation of antigen-specific T H 17 cells occurring independently in both LN and lung. Thus, self-assembling peptide nanofiber vaccines may ...
- Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulationson August 5, 2020 at 2:03 am
We found that both approaches promote the concentration of Env immunogens in B cell areas, with antigen accumulation in hundreds of follicles within a single LN. Nanoparticle immunogens were further ...
- Researchers describe nanoparticles behavior in vivoon August 4, 2020 at 12:17 pm
Nanoparticles are actively employed in medicine as contrast agents as well as for diagnosis and therapy of various diseases. However, the development of novel multifunctional nanoagents is impeded by ...
- Researchers describe nanoparticle behavior in vivoon August 4, 2020 at 7:22 am
(Nanowerk News) Nanoparticles are actively employed in medicine as contrast ... Alternatively, the excessively long circulation time may lead to the accumulation of the particles in healthy tissues, ...
- Two-step targeting strategy can increase clinical translation of nanoparticle-based therapieson July 26, 2020 at 5:00 pm
This two-step targeting strategy therefore paves the way to overcome the peripheral 'off-target' nanoparticle accumulation, increasing the clinical translation of nanoparticle-based therapies.
via Bing News