In one of the most comprehensive laboratory studies of its kind, Rice University scientists traced the uptake and accumulation of quantum dot nanoparticles from water to plant roots, plant leaves and leaf-eating caterpillars.
The study, one of the first to examine how nanoparticles move through human-relevant food chains, found that nanoparticle accumulation in both plants and animals varied significantly depending upon the type of surface coating applied to the particles. The research is available online in the American Chemical Society’s journal Environmental Science & Technology.
“With industrial use of nanoparticles on the rise, there are increasing questions about how they move through the environment and whether they may accumulate in high levels in plants and animals that people eat,” said study co-author Janet Braam, professor and chair of the Department of BioSciences at Rice.
Braam and colleagues studied the uptake of fluorescent quantum dots by Arabidopsis thaliana, an oft-studied plant species that is a relative of mustard, broccoli and kale. In particular, the team looked at how various surface coatings affected how quantum dots moved from roots to leaves as well as how the particles accumulated in leaves. The team also studied how quantum dots behaved when caterpillars called cabbage loopers (Trichoplusia ni) fed upon plant leaves containing quantum dots.
“The impact of nanoparticle uptake on plants themselves and on the herbivores that feed upon them is an open question,” said study first author Yeonjong Koo, a postdoctoral research associate in Braam’s lab. “Very little work has been done in this area, especially in terrestrial plants, which are the cornerstone of human food webs.”
Some toxins, like mercury and DDT, tend to accumulate in higher concentrations as they move up the food chain from plants to animals. It is unknown whether nanoparticles may also be subject to this process, known as biomagnification.
The Latest on: Nanoparticle accumulation
via Google News
The Latest on: Nanoparticle accumulation
- The entry of nanoparticles into solid tumourson January 13, 2020 at 8:51 am
The concept of nanoparticle transport through gaps between endothelial ... that understanding these active pathways will unlock strategies to enhance tumour accumulation. All the annotated and ...
- Nanoparticles as Computed Tomography Contrast Agentson December 29, 2019 at 4:00 pm
However, the active targeting has additive values; the nanoparticles home selectively onto specific tumors and remain at the tumor site for an extended time, thereby increasing the local accumulation ...
- Stimulus-responsive Macromolecules and Nanoparticles for Cancer Drug Deliveryon December 23, 2019 at 4:00 pm
Summary of drug-delivery vehicles and stimulus-responsive drug ... of lymphatics allow increased accumulation of systemically delivered macromolecules and nanoparticles in tumor tissue.
- Oriented attachment induces fivefold twins by forming and decomposing high-energy grain boundarieson November 28, 2019 at 11:03 am
We discovered two different mechanisms for forming fivefold twinned nanoparticles that are driven by the accumulation and elimination of strain. This was accompanied by decomposition of grain ...
- Chemo-Loaded Nanoparticles Piggyback on Red Blood Cells to Treat Lung Canceron November 14, 2019 at 7:02 am
However, this has met with mixed success, with one of the major hurdles being a lack of nanoparticle accumulation at tumor sites and rapid nanoparticle clearance by the liver and spleen.
- Evaluating differential nanoparticle accumulation and retention kinetics in a mouse model of traumatic brain injury via K trans mapping with MRIon November 6, 2019 at 2:29 am
Some groups have sought to improve outcomes by minimizing BBB opening following TBI, but the opening also provides an opportunity for systemically administered drugs or nanoparticles (NPs ...
- Drug-Loaded Synthetic Nanoparticles Can Target Lung Cancer Cellson October 24, 2019 at 5:00 pm
Because conventional chemo drugs indiscriminately kill all rapidly dividing cells to halt the growth of cancer, these selective nanoparticles could decrease side effects by reducing drug accumulation ...
- Bioinspired nanoparticles remodel tumor stroma to enhance nanoparticle accessibility to cancer cellson July 26, 2019 at 11:17 am
Although nanosized formulations can reach the tumor sites with high accumulation, they are usually ineffective ... barriers and augmenting the accessibility of second-wave nanoparticles to cancer ...
- New ceria nanoparticles attack Parkinson's disease from three frontson July 27, 2018 at 5:23 am
Accumulation of reactive oxygen species damages the neurons ... To solve these problems, IBS nanoparticle researchers have devised three types of ceria nanoparticles with different sizes and surface ...
- Machine Learning for Building Personalized Cancer Nanomedicines: Interview with Dr. Daniel Helleron February 15, 2018 at 12:42 pm
Nanoparticles can help to increase drug accumulation in the tumor, and reduce off-target tissue exposure, helping to increase drug effectiveness and reduce side effects. This research team has ...
via Bing News