Researchers at Siriraj Hospital, part of Mahidol University, claim they have developed the world’s first “antibody treatment” that could cure Ebola virus infections.
At least a year away from practical application, the antibody was called a significant step toward finding a cure for the disease, which has killed more than 3,000 people in West Africa this year. Currently there is no cure, although several experimental drugs have been deployed in the battle against the epidemic.
Meanwhile, the World Health Organisation said Wednesday it has at least 1,500 doses of an experimental vaccine ready to be given to medical personnel fighting the disease in Africa. The German Press Agency said WHO has been working to speed up testing of two experimental-stage vaccines – chimpanzee adenovirus developed by British company GlaxoSmithKline and a US government laboratory, and VSV developed by Canada’s health agency.
Siriraj’s antibody – developed with the use of human genes, not the Ebola virus itself – is small enough to enter infected cells and access virus proteins within them, doctors said. The antibody is five times smaller than what is being tested in the United States, said Dr Udom Kachinthorn, dean of the medical science faculty at Siriraj.
He said the Thai antibody had different structures and mechanisms and was more efficient, making a cure derived from it more effective.
Researchers used synthesised Ebola genes in development of the antibody and tested them on samples of haemorrhagic-fever viruses similar, but less virulent, than the five Ebola variants.
Thailand does not possess a Biosafety Level 4 facility required to test on the Ebola virus itself. Doctors also admitted they have not been in contact with the World Health Organisation regarding the purported cure.
The next step will be to conduct testing on animals before moving on to human trials. If the tests are successful, the antibody would then need to be mass produced. That step would be at least a year away, Dr Udom cautioned.
However, he added, the Thai pharmaceutical sector could expedite the drug’s development, pending more tests. To facilitate that, Siam Bioscience, a joint Thai-Cuban pharmaceutical venture launched this year, will join in the research.
Doctors, eager to promote the antibody treatment as the first of its kind developed in Thailand, emphasised it is not a vaccine. Dr Wanpen Chaicumpa, head of the Ebola antibody-development team, said the treatment would be administered after infection through injection.
The Latest on: Ebola cure
via Google News
The Latest on: Ebola cure
- FDA to Purell: Stop claiming your hand sanitizers eliminate Ebola and the fluon January 27, 2020 at 7:04 pm
The U.S. Food and Drug Administration is giving the maker of Purell products a stern warning: Stop making unproven claims that over-the-counter hand sanitizers help eliminate Ebola, MRSA or the flu.
- FDA to Purell: Stop claiming your hand sanitizers eliminate Ebola, MRSA & fluon January 27, 2020 at 1:54 pm
The agency said it was not aware of any hand sanitizers that have been tested against Ebola viruses, including Purell's products ... "because they are intended for the diagnosis, cure, mitigation, ...
- FDA to Purell: Stop claiming hand sanitizers eliminate Ebola, MRSA, fluon January 27, 2020 at 1:46 pm
The agency said it was not aware of any hand sanitizers that have been tested against Ebola viruses, including Purell’s products ... “because they are intended for the diagnosis, cure, mitigation, ...
- FDA warns Purell maker to stop claiming its hand sanitizers eliminate Ebola and MRSAon January 27, 2020 at 1:26 pm
A 'warning letter' says numerous marketing claims potentially position Purell's sanitizing products as pharmaceutical drugs.
- Gilead Considering Ebola Drug as Potential Coronavirus Treatmenton January 23, 2020 at 6:48 pm
Gilead (NASDAQ:GILD) announced Thursday that it was evaluating whether its experimental Ebola treatment could be used to treat the coronavirus. In an attempt to prevent the virus from spreading, China ...
- Gilead assessing Ebola drug as possible coronavirus treatmenton January 23, 2020 at 3:52 pm
Gilead Sciences Inc said on Thursday it was assessing whether its experimental Ebola treatment could be used to treat coronavirus infection. “Gilead is in active discussions with researchers and ...
- Coronavirus outbreak: Gilead assessing Ebola drug as possible treatmenton January 23, 2020 at 12:25 pm
Gilead Sciences Inc. said Thursday it was assessing whether its experimental Ebola treatment could be used to treat coronavirus infection. Continue Reading Below "Gilead is in active discussions with ...
- Gilead assessing potential use of Ebola drug as China virus treatmenton January 23, 2020 at 11:02 am
"Gilead is in active discussions with researchers and clinicians in the United States and China regarding the ongoing Wuhan coronavirus outbreak and the potential use of remdesivir as an ...
- Despite outbreak, Ebola treatment and vaccine represent ‘resounding scientific success’on January 16, 2020 at 2:30 pm
But the death toll would be much higher without the unprecedented rate of medical progress in treatment. Special correspondent Monica Villamizar reports. Last month, the U.S. Food and Drug ...
- Specialist technique used to study drugs completed for first time during Ebola outbreakon January 15, 2020 at 12:55 pm
A specialist technique used to study drugs has been completed for the first time during an outbreak of Ebola virus disease. Although treatment with TKM-130803 did not appear to improve survival ...
via Bing News