Several decades ago, a number of clinics used LSD to treat alcoholism with some success. But until now, no research has pulled together the results of these trials to document exactly how effective LSD was.
Now a new meta-analysis of randomized controlled trials of the drug, available in the Journal of Psychopharmacology, published by SAGE, provides evidence for a clear and consistent beneficial effect of LSD for treating alcohol dependency.
Teri Krebs and Pål-Ørjan Johansen are both affiliated with the Department of Neuroscience at the Norwegian University of Science and Technology (NTNU), Trondheim, Norway, Laboratory for Integrative Psychiatry, Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA and Department of Psychiatry, Harvard Medical School, Boston, MA, USA.They spotted a gap in the understanding of lysergic acid diethylamide’s (LSD’s) potential for alcoholism treatment. No researcher had ever performed a quantitative meta-analysis of previous clinical trials using the drug.
Krebs and Johansen set out to independently extract data from previous randomized, controlled clinical trials, pooling their results. They identified six eligible trials, all carried out in the late 1960s and early 1970s. These included 536 participants, the vast majority of whom were male in-patients enrolled in alcohol-focused treatment programs. Individuals with a history of schizophrenia or psychosis were excluded from the original trials. The control conditions included low-dose LSD, stimulants, or non-drug control conditions. Each trial used clearly defined treatment-independent and standardized methods to assess outcomes on alcohol misuse.
While the experiments varied in the dosage used and the type of placebo physicians administered to patients, LSD had a beneficial effect on alcohol misuse in every trial. On average, 59 percent of LSD patients and 38 percent of control patients were improved at follow-up using standardized assessment of problem alcohol use. There was also a similar beneficial effect on maintained abstinence from alcohol. The positive effects of a single LSD dose – reported both in these and in other, non-randomized trials – lasts at least six months and appears to fade by 12 months.
Regarding the lasting effects of the LSD experience in alcoholics, investigators of one trial noted, “It was rather common for patients to claim significant insights into their problems, to feel that they had been given a new lease on life, and to make a strong resolution to discontinue their drinking”. And investigators of another trial noted, “It was not unusual for patients following their LSD experience to become much more self-accepting, to show greater openness and accessibility, and to adopt a more positive, optimistic view of their capacities to face future problems.”
The Latest on: Alcoholism treatment
via Google News
The Latest on: Alcoholism treatment
- Alcohol vaping machine confiscated from Dakota County bar; health risks unclearon October 30, 2019 at 6:52 pm
White House launches website aimed at addiction treatment Chronic wasting fears force DNR to ‘scramble’ over deer carcass disposal in some areas I-35W bridge will glow orange Monday night to raise ...
- Legislators and others push for stronger regulation of addiction-treatment industry at Costa Mesa hearingon October 30, 2019 at 5:03 pm
Patricia Bates (R-Laguna Niguel) — listened to input from residents and panels of speakers about how best to tackle problems in the addiction-treatment industry. “There’s a ton of work that we need to ...
- HHS makes finding addiction treatment easier with FindTreatment.govon October 30, 2019 at 1:45 pm
In another effort to combat the opioid crisis, the Department of Health and Human Services has unveiled an addiction treatment locator website, FindTreatment.gov. The goal of the website is to make it ...
- Trump Administration Launches Addiction Treatment Websiteon October 30, 2019 at 11:24 am
FindTreatment.gov is designed to be a resource for people battling opioid addiction. WASHINGTON (AP) — The Trump administration has unveiled a website aimed at helping millions of Americans with ...
- Feds Unveil New and Improved Addiction Treatment Locator Websiteon October 30, 2019 at 11:24 am
"In fact, it can be lifesaving." "Addiction demands treatment, not judgment. Now, thanks to FindTreatment.gov, more Americans will have easier ways to the find the treatment that they or loved ones ...
- White House launches website to help people find addiction treatmenton October 30, 2019 at 7:25 am
The White House on Wednesday launched a website aimed at making it easier for people to find addiction treatment, with a particular focus on fighting the opioid epidemic. The website findtreatment.gov ...
- Trump administration unveils new website to help people find drug addiction treatmenton October 30, 2019 at 6:29 am
U.S. Drug Czar Jim Carroll says over 13,000 facilities have registered with www.findtreatment.gov and you can find a treatment center by your zip code.
- White House launches website aimed at addiction treatmenton October 30, 2019 at 2:10 am
WASHINGTON (AP) — The Trump administration has unveiled a website aimed at helping millions of Americans with substance abuse issues learn about and locate treatment options. FindTreatment.gov is the ...
- Our View: The stigma of addiction and treatmenton October 29, 2019 at 9:07 pm
Unfortunately, that acceptance may still be wider than it is deep. A new report from the state Medication Assisted Treatment Commission, released earlier this month, made clear that there are still ...
- Assemblywoman’s forum in Costa Mesa will discuss oversight of addiction-treatment industryon October 29, 2019 at 12:53 pm
Californians seeking rehab deserve more.” While addiction-treatment facilities and sober-living homes — which typically house recovering alcoholics and drug addicts, who are considered disabled under ...
via Bing News