Mechanism uncovered could also help preserve neuron function in Alzheimer’s disease, traumatic brain injury and other neurodegenerative conditions
Research presented by Dr. Lynn Raymond, from the University of British Columbia, shows that blocking a specific class of glutamate receptors, called extrasynaptic NMDA receptors, can improve motor learning and coordination, and prevent cell death in animal models of Huntington disease. As Huntington disease is an inherited condition that can be detected decades before any clinical symptoms are seen in humans, a better understanding of the earliest changes in brain cell (neuronal) function, and the molecular pathways underlying those changes, could lead to preventive treatments that delay the onset of symptoms and neurodegeneration. “After more than a decade of research on the pre-symptomatic phase of Huntington disease, markers are being developed to facilitate assessment of interventional therapy in individuals carrying the genetic mutation for Huntington disease, before they become ill. This will make it possible to delay onset of disease,” says Dr. Raymond.
The Latest on: Huntington’s disease
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The Latest on: Huntington’s disease
- Disease detectives track an invisible culpriton July 6, 2020 at 3:58 pm
Contact tracers in two cities, one in the north and one in the south, are trying to prevent Covid-19 infections.
- Dix Hills Pool Open To Town Of Huntington Residents On Weeknightson July 6, 2020 at 11:33 am
The opening is in addition to weekend hours. Residents must reserve a time slot and wear a mask to gain entry, Town officials say.
- Living with Huntington’s diseaseon July 3, 2020 at 6:55 pm
ABC News’ Linsey Davis follows two families grappling with the rare genetic disorder Huntington’s disease, compared to ALS, Parkinson’s disease and Alzheimer's disease all in one.
- To everything there is a season, including heart diseaseon July 2, 2020 at 5:05 pm
A growing body of research suggests heart attacks, angina and other heart events increase during winter and summer. Now, a new study could explain why. Researchers reviewed an international registry ...
- AHA News: To Everything There Is a Season, Including Heart Diseaseon July 2, 2020 at 11:56 am
Heart attack is a type of acute coronary syndrome, which occurs when the blood supply to the heart muscle is suddenly decreased or blocked. Using images of the fatty deposits in participants' coronary ...
- Novel pathology could improve diagnosis and treatment of Huntington's and other diseaseson June 30, 2020 at 9:29 am
Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease. The article, published in Brain Pathology, describes ...
- CVS opens new coronavirus testing sites in Anaheim, Huntington Park, Inglewood and Long Beachon June 26, 2020 at 1:48 pm
CVS Health is expanding its COVID-19 no-cost testing program by adding 35 more test sites Friday at select CVS Pharmacy drive-thrus across California — including four locations in Los Angeles and ...
- Cabell Huntington Hospital Counseling Center Now Offering Telehealth Serviceson June 26, 2020 at 8:04 am
the Centers for Disease Control (CDC) is reporting depression and stress are on the rise. Fear, anxiety and worry about the interruption of life can have a negative effect on mental health. To help ...
- Parkinson’s Disease Symptoms Reversed by Replacing Lost Neurons in Miceon June 26, 2020 at 5:00 am
Scientists converted astrocytes to functional neurons by depleting the RNA-binding protein PTB, reversing symptoms in a mouse model of Parkinson's disease.
- Winston-Salem woman raises awareness about Huntington’s diseaseon June 24, 2020 at 5:23 pm
A local woman is advocating for compassion and awareness of a neurodegenerative disease that runs in her family. At 34 years old Lauren Holder makes all of her father ...
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