Mechanism uncovered could also help preserve neuron function in Alzheimer’s disease, traumatic brain injury and other neurodegenerative conditions
Research presented by Dr. Lynn Raymond, from the University of British Columbia, shows that blocking a specific class of glutamate receptors, called extrasynaptic NMDA receptors, can improve motor learning and coordination, and prevent cell death in animal models of Huntington disease. As Huntington disease is an inherited condition that can be detected decades before any clinical symptoms are seen in humans, a better understanding of the earliest changes in brain cell (neuronal) function, and the molecular pathways underlying those changes, could lead to preventive treatments that delay the onset of symptoms and neurodegeneration. “After more than a decade of research on the pre-symptomatic phase of Huntington disease, markers are being developed to facilitate assessment of interventional therapy in individuals carrying the genetic mutation for Huntington disease, before they become ill. This will make it possible to delay onset of disease,” says Dr. Raymond.
The Latest on: Huntington’s disease
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The Latest on: Huntington’s disease
- Weyburn girl, 9, raises money for Huntington's disease with handcrafted keychainson June 28, 2020 at 5:04 pm
A young girl in Weyburn has found a crafty way to bring awareness to Huntington’s disease, something that has closely affected her family.
- CVS opens new coronavirus testing sites in Anaheim, Huntington Park, Inglewood and Long Beachon June 26, 2020 at 1:48 pm
CVS Health is expanding its COVID-19 no-cost testing program by adding 35 more test sites Friday at select CVS Pharmacy drive-thrus across California — including four locations in Los Angeles and ...
- Cabell Huntington Hospital Counseling Center Now Offering Telehealth Serviceson June 26, 2020 at 8:04 am
the Centers for Disease Control (CDC) is reporting depression and stress are on the rise. Fear, anxiety and worry about the interruption of life can have a negative effect on mental health. To help ...
- Parkinson’s Disease Symptoms Reversed by Replacing Lost Neurons in Miceon June 26, 2020 at 5:00 am
Scientists converted astrocytes to functional neurons by depleting the RNA-binding protein PTB, reversing symptoms in a mouse model of Parkinson's disease.
- Winston-Salem woman raises awareness about Huntington’s diseaseon June 24, 2020 at 5:23 pm
A local woman is advocating for compassion and awareness of a neurodegenerative disease that runs in her family. At 34 years old Lauren Holder makes all of her father ...
- Ohio State Conducts First Gene Therapy Clinical Trial For Huntington’s Diseaseon June 23, 2020 at 9:54 am
In a worldwide first, surgeons at The Ohio State University Wexner Medical Center have treated two patients with Huntington's ...
- Yasaman Gholamalipour awarded fellowship by Huntington’s Disease Society of Americaon June 23, 2020 at 7:09 am
UMass Medical School postdoctoral associate Yasaman Gholamalipour, PhD, was awarded the Huntington’s Disease Society of America Berman-Topper Family HD Career Development Fellowship for 2020.
- How COVID-19 is changing the way doctors care for patients with Huntington’s disease | Expert Opinionon June 23, 2020 at 4:06 am
While there’s no substitute for personal contact, we were amazed to discover that telemedicine allowed our Huntington's patients to teach us skills we wouldn’t have learned had we met them in the ...
- Parents’ joy as pioneering scientists save newborn twins from cruel genetic Huntington’s diseaseon June 21, 2020 at 6:00 am
The look of love between Juliana Queen and her twin babies is unmistakable and, by her side, five-year-old daughter Amelia beams with pride.
- Treatment underway in study of uniQure gene therapy in Huntington's diseaseon June 19, 2020 at 4:49 am
The first two participants have been treated in a 26-subject Phase 1/2 clinical trial evaluating uniQure's (NASDAQ:QURE) AMT-130 in patients with Huntington's disease (HD), an inherited neurod ...
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