Wounds may heal more quickly if exposed to low-intensity vibration, report researchers at the University of Illinois at Chicago.
The finding, in mice, may hold promise for the 18 million Americans who have type 2 diabetes, and especially the quarter of them who will eventually suffer from foot ulcers. Their wounds tend to heal slowly and can become chronic or worsen rapidly. Timothy Koh, UIC professor of kinesiology and nutrition in the UIC College of Applied Health Sciences, was intrigued by studies at Stony Brook University in New York that used very low-intensity signals to accelerate bone regeneration. “This technique is already in clinical trials to see if vibration can improve bone health and prevent osteoporosis,” Koh said. Koh and his coworkers at UIC collaborated with Stefan Judex of Stony Brook to investigate whether the same technique might improve wound healing in diabetes.
The new study, using an experimental mouse model of diabetes, is published online in the journal PLOS One. The low-amplitude vibrations are barely perceptible to touch. “It’s more like a buzz than an earthquake,” said Eileen Weinheimer-Haus, UIC postdoctoral fellow in kinesiology and nutrition, the first author of the study. The researchers found that wounds exposed to vibration five times a week for 30 minutes healed more quickly than wounds in mice of a control group. Wounds exposed to vibration formed more granulation tissue, a type of tissue important early in the wound-healing process.
Vibration helped tissue to form new blood vessels — a process called angiogenesis — and also led to increased expression of pro-healing growth factors and signaling molecules called chemokines, Weinheimer-Haus said. “We know that chronic wounds in people with diabetes fail to form granulation tissue and have poor angiogenesis, and we believe these factors contribute to their wounds’ failure to heal,” said Koh. He and his colleagues want to determine whether the changes they see in cell populations and gene expression at wound sites underlie the observed improvement in healing. “The exciting thing about this intervention is how easily it could be translated to people,” Koh said. “It’s a procedure that’s non-invasive, doesn’t require any drugs, and is already being tested in human trials to see if it’s protective of bone loss.”
A clinical study, in collaboration with Dr. William Ennis, director of the Wound Healing Clinic at UIC, is planned, Koh said.
The Latest on: Low-intensity vibration
via Google News
The Latest on: Low-intensity vibration
- 13 pieces of home gym equipment to keep up your fitness levelson July 10, 2020 at 8:53 am
If, like us, you tried to buy fitness equipment in lockdown, you’ll know there wasn’t much variety available. Now, with shops reopened, stock levels are up and you can pick the kit best suited to your ...
- Shopping for a Sex Toy Can Be Overwhelming. This Guide Can Helpon June 22, 2020 at 5:00 pm
Dame Fin Bullet vibrator About the size of a battery, bullet vibrators provide buzzy, low-intensity vibration to your bits. They fit inside most harnesses to give the strap-on wearer stimulus.
- The new normal: A glacial lake outburst flood in Hassanabad valley of Hunza causes displacement and relocationon June 13, 2020 at 5:00 pm
Abbas says, “The vibration from the GLOF event causes ... net snout advance minimal or even negative.” He adds, “The low-intensity GLOF incidents on June 23, 2019, and May 29, 2020, were ...
- Unprecedented dipole alignment in α-phase nylon-11 nanowires for high-performance energy-harvesting applicationson June 9, 2020 at 5:00 pm
These phenomena indicate that the low intensity and limited thermal stability of remanent ... driven by a signal generator (Thurlby Thandar TG1304) to generate vibration motion of the impacting arm ...
- Israeli solutions to help you sleep soundly during difficult timeson June 7, 2020 at 11:25 pm
Quit Snoring will then issue an electronic nudge – a vibration or prerecorded sound – when it ... high-intensity blue light, low-intensity blue light, high-intensity red light and low-intensity red ...
- Tibia Shaft Fractures: Costly Burden of Nonunionson May 28, 2020 at 5:00 pm
A common approach to delayed unions is expectant management, accompanied by non-invasive therapies such as low-intensity pulsed ultrasound, [12–14] or vibration.  When healing fails within a ...
- Ride with greater peace of mind with the Varia™ RVR315 and RTL515 from Garmin®on May 12, 2020 at 5:00 pm
What’s more, the Varia RTL515 now includes peloton mode, providing a low-intensity flash that is easier on other ... In addition to the graphics, tone and vibration alerts will let cyclists know when ...
- Region not used to quake activityon June 13, 2019 at 9:08 pm
When Juniata College geology professor Katy Johanesen heard a low rumbling and felt a vibration while at her ... didn’t expect any more as it was a low intensity quake, but aftershocks may ...
- Hormonal responses to a single session of wholebody vibration exercise in older individualson September 20, 2018 at 3:39 pm
boa.org.uk Objective Whole-body vibration (WBV) has been recently suggested as an alternative form of exercise. In this study, the acute effects of a single session of WBV exercise on anabolic ...
- Ultrasonic-assisted wet processingon August 18, 2018 at 12:02 pm
The ceramic ring is fit into a metal body, which enhances the vibration reaches its maximum ... Application of Ultrasonic can be thus be of low intensity and High intensity.
via Bing News