New global study led by ESMO reveals a pandemic of intolerable pain affecting billions, caused by over-regulation of pain medicines
A ground-breaking international collaborative survey, published today in Annals of Oncology, shows that more than half of the world’s population live in countries where regulations that aim to stem drug misuse leave cancer patients without access to opioid medicines for managing cancer pain.
The results from the Global Opioid Policy Initiative (GOPI) project show that more than 4 billion people live in countries where regulations leave cancer patients suffering excruciating pain. National governments must take urgent action to improve access to these medicines, says the European Society for Medical Oncology, leader of a group of 22 partners that have launched the first global survey to evaluate the availability and accessibility of opioids for cancer pain management.
“The GOPI study has uncovered a pandemic of over-regulation in much of the developing world that is making it catastrophically difficult to provide basic medication to relieve strong cancer pain,” says Nathan Cherny, Chair of the ESMO Palliative Care Working Group and lead author of the report, from Shaare Zedek Medical Center, Jerusalem, Israel. “Most of the world’s population lacks the necessary access to opioids for cancer pain management and palliative care, as well as acute, post-operative, obstetric and chronic pain.”
“When one considers that effective treatments are cheap and available, untreated cancer pain and its horrendous consequences for patients and their families is a scandal of global proportions,” Cherny says.
The study conducted in Africa, Asia, Latin America & the Caribbean and the Middle East assessed the availability of the seven opioid medications considered to be essential for the relief of cancer pain by the WHO Model List of Essential Medicines and the International Association for Hospice and Palliative Care. Those essential medications include codeine, oral oxycodone, transdermal fentanyl, immediate and slow release oral morphine, as well as injectable morphine, and oral methadone.
While there are problems with the supply of these medicines in many countries, the main problem is over-regulation that makes it difficult for healthcare professionals to prescribe and administer them for legitimate medical use, the authors say.
“This is a tragedy born out of good intentions,” says Cherny. “When opioids are over-regulated, the precautionary measures to prevent abuse and diversion are excessive and impair the ability of healthcare systems to relieve real suffering. The GOPI study has uncovered over-regulation in much of the developing world.”
“The next step is for international and local organisations working alongside governments and regulators to thoughtfully address the problems,” adds study co-author James Cleary, Director of the Pain and Policy Studies Group and Founding Director of the Palliative Medicine at the UW Carbone Cancer Center, Madison, Wisconsin, USA.
“Regulatory reform must be partnered with education of healthcare providers in the safe and responsible use of opioid medication, education of the public to destigmatize opioid analgesics and improved infrastructure for supply and distribution,” he says.
The Latest Google Headlines on:
The Latest Bing News on:
- Artelo Biosciences Expands Stony Brook Commercial License Agreement for FABP5 Platform for Development of Lead Cancer, Pain and Inflammation Compoundson June 29, 2020 at 5:38 am
Artelo Biosciences, Inc. (NASDAQ: ARTL), a clinical stage biopharmaceutical company focused on the development of therapeutics ...
- White Cancer Patients' Perception of Gender and Ethnic Differences in Pain Experienceon June 14, 2020 at 5:00 pm
Five themes were identified through the analysis process. First, the participants perceived that pain accompanies cancer throughout the diagnosis and treatment process. Second, the participants ...
- Where Will Sorrento Therapeutics Be in 1 Year?on June 12, 2020 at 3:54 am
Currently, resiniferatoxin is being tested in clinical trials for two indications: knee osteoarthritis pain relief and treatment of terminal cancer pain. The goal of the resiniferatoxin study is ...
- Could Sorrento Therapeutics Be a Millionaire-Maker Stock?on June 10, 2020 at 3:57 am
Image source: Getty Images. Sorrento's prospects of survival are favorable as a result of focused pipeline development in under-served niches like terminal cancer pain and treatment-resistant ...
- How to Cope with Cancer Pain - Latest News and Research Updateson June 9, 2020 at 5:00 pm
Medindia provides you with the latest news and research breakthroughs on How to Cope with Cancer Pain. Please find 161 such items on this topic. Electrical Impulses Could Relieve Chronic Pain ...
- 'Disturbing Finding' on Black Patients With Cancer in Need of Opioidson June 8, 2020 at 11:59 am
The opioid epidemic has led to a decline in the use of opioids for end-of-life pain care in patients with cancer that is disproportionately felt by black patients, reveals a large-scale analysis ...
- Global Cancer Pain Market Size Report 2020 Industry Research Report by Manufactures, Types, Applications and Market Dynamicson June 6, 2020 at 2:01 am
-Wall Mounted CD Player Market Size Report 2020-2024 Raw Materials Sources, Major Manufacturers, Export and Import by Regions with Impact of COVID-19 on Industry -Shrink Bundling Films Market Size ...
- The global pain management devices market is expected to reach US$ 8,388.67 million in 2027 from US$ 4,527.31 million in 2019on June 5, 2020 at 7:54 am
cancer, and other chronic disorders associated with pain. Therefore, the demand for pain management devices is higher among the geriatric population. Increasing geriatric population is a ...
- Theralase CEO Interviewed by CBC TV about Progress in Anti-Cancer and Pain Researchon June 4, 2020 at 5:00 pm
It is estimated that $91 Billion is spent on the war on cancer and $100 Billion on pain in the United States, annually. For the last 20 years, Theralase has designed and manufactured patented ...
- Cancer Pain Affects the Quality of Life of Asian Patients Significantlyon June 1, 2020 at 5:00 pm
In order to implement more effective policies for cancer pain management, a better understanding of current practices and their effect on patients are needed. The ACHEON study included a survey-based ...
The Latest Google Headlines on:
Untreated Cancer Pain
The Latest Bing News on:
Untreated Cancer Pain
- Finding undiagnosed patients with hepatitis C infection: an application of artificial intelligence to patient claims dataon June 29, 2020 at 2:25 am
Hepatitis C virus (HCV) remains a significant public health challenge with approximately half of the infected population untreated and undiagnosed. In this retrospective study, predictive models were ...
- Skin cancer symptoms: Two lesser known warning signs found on the lips and nailson June 25, 2020 at 1:45 am
SKIN cancer symptoms are not always just a matter of a new dark spot found on the body. Sometimes the warning signs can be found elsewhere, including on a person's lips or fingernails. Dry lips or a ...
- Myovant Sciences Announces Positive Study Results For Endometriosis Medicationon June 23, 2020 at 4:59 am
Myovant Sciences has announced positive results for its second Phase 3 study into a medical treatment that may present an alternative to surgery for people with endometriosis.
- Doctors recommend screening for anxiety in children, adolescentson June 17, 2020 at 8:28 pm
One local doctor said untreated anxiety in kids can lead to substance abuse and other related mental health conditions as they get older.
- There's a hidden crisis threatening lives alongside Covid-19: the lack of routine treatmenton June 17, 2020 at 1:00 am
Serious illnesses going untreated or undiagnosed as the NHS focuses on coronavirus are tragic – and a health time-bomb, says Guardian columnist Frances Ryan ...
- Helicobacter infections hit Bhutan’s happiness.on June 16, 2020 at 11:11 pm
"Having observed such a high prevalence of the H. pylori pathogen, one could be surely unconvinced that Bhutan could be called a really happy country," Rui ...
- VENCLEXTA/VENCLYXTO Plus Azacitidine Demonstrates Overall Survival Benefit and Improved Remission Rateson June 15, 2020 at 1:17 pm
AbbVie announced the positive results from the VIALE-A (M15-656) trial, which demonstrated that previously-untreated patients with acute myeloid leukemia who were ineligible for intensive chemotherapy ...
- Helicobacter infections hit Bhutan's happinesson June 11, 2020 at 5:56 am
Over 66% of Bhutan's population may be harbouring Helicobacter pylori bacteria, which is responsible for ulcers of the gastro-intestinal tract that, left untreated, may lead to cancer, a new study ...
- Man who died of cancer went untreated 'for over a year' because of DHB's IT error - reporton June 8, 2020 at 12:26 am
The Hawke’s Bay District Health Board has been put to task following an IT system failure which saw a man with cancer go untreated for ... for a man who had pain in his tailbone area.
- Identifying and Treating Depression in Women With Cancer: A Primary Care Approachon June 7, 2020 at 5:00 pm
Depression left untreated ... cancer and provides the primary care clinician with tools for better diagnosis and management. Dr. Strouse is Director of Psychosocial Services and of the Cancer Pain ...