Aging process in the human body is greatly influenced by the action of free radicals (byproducts of our own metabolism), but can be slowed down without the need to consume special dietary supplements if the HGF protein production, naturally found in the liver, is increased.
This same protein helps to stop and reverse the destruction of the organ caused by cirrhosis, alcoholic liver disease or the consumption of drugs against tuberculosis like Isoniazid or Rifampicin.
Mexican scientists form the Metropolitan Autonomous University (UAM) discovered the antioxidant effects of the HGF protein and also proved in their laboratory its liver regenerating effects. These effects had been planted as hypothesis by other research groups across the world, but had never been successfully tested.
This findings set the base to build a new line of therapeutic attention to stop the premature aging of the human body caused by exposure to different toxins, like alcohol. The next challenge for the research group at UAM is to develop a method to make the liver increase or decrease the production of the HGF protein because it cannot be eaten or ingested as a common drug.
“What we discovered was not a new antioxidant, like vitamin C that can be found in orange juice or dietary supplements. What we discovered was the action of a liver produced protein that turns on, regulates and modulates the natural defense mechanisms of our body against free radicals”, Luis Enrique Gómez Quiroz, head of the project, explained during the interview.
Mexican research started on 2006 and has counted with the collaboration of the Laboratory of Experimental Carcinogenesis form the National Cancer Institute of the United States.
HGF stands for Hepatocytes (type of cell that composes the main tissue of the liver) Growth Factor which was identified 35 years ago in Japan but its anti-aging effects were discovered in Mexico City.
This research group also proved, in mice with cirrhosis, that when HGF levels are low the disease advances at a rapid pace and that it stops when this protein is present at a higher concentration.
“HGF turns on routes to produce natural antioxidant compounds in our body, for example a small tripeptide (a molecule composed by three amino acids, which work as construction bricks in our body) called glutathione which works as a very important antioxidant and liver protector.
“We have seen in this laboratory that HGF notably increases the production of glutathione and other protector compounds, not just for the liver, but for all the organs in the body: lungs, kidneys, pancreas, etc. When this natural antioxidant is induced to increase its production, it protects the body from the toxic effects of many compounds like alcohols”, said Gómez Quiroz.
Go deeper with Bing News on:
- Intercept Pharmaceuticals Inc (ICPT) Q2 2020 Earnings Call Transcripton August 10, 2020 at 1:43 pm
Welcome to the Second Quarter 2020 Intercept Pharmaceuticals Earnings Conference Call. At this time, all participants are in a listen-only mode. After the speakers' remarks, there will be a ...
- Priest gets liver transplant -- and the donor is a former parishioneron August 10, 2020 at 1:38 pm
WASHINGTON -- Thirty-seven days after his liver transplant, Father John Mack could catalog the things he can do in recovery.
- Intercept Pharmaceuticals (ICPT) Q2 2020 Results - Earnings Call Transcripton August 10, 2020 at 11:28 am
Q2 2020 Earnings Call August 10, 2020 8:30 AM ET. Executives. Lisa M. DeFrancesco - Intercept Pharmaceuticals, Inc. Mark E. Pruzanski ...
- Roger Williams obituaryon August 10, 2020 at 9:10 am
Physician who created the UK’s first liver transplant programme and worked with George Best to highlight the dangers of alcohol ...
- Intercept Pharmaceuticals Reports Second Quarter 2020 Financial Results, Announces Updates to Financial Guidance and Provides Business Updateon August 10, 2020 at 4:00 am
Worldwide Ocaliva net sales of $77.2 million in the second quarter 2020, representing 17% growth over the prior year quarter. Intercept issues 2020 Ocaliva Net Sales Guidance of $ ...
Go deeper with Google Headlines on:
Go deeper with Bing News on:
- Malaria Treatment May Be Found by Targeting the Hoston August 12, 2020 at 5:00 am
Malaria study suggests targeting enzymes from the human host, rather than from the pathogen itself, could offer effective treatment ...
- Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasison August 10, 2020 at 10:31 am
TMPRSS2 is an important membrane-anchored serine protease involved in human prostate cancer progression A serine protease physiologically often comes together with ...
- Next-generation Sequencingon August 6, 2020 at 5:00 pm
and CAF secretion of HGF in increased proteolysis and invasiveness of DCIS cells;  The term 'overdiagnosis' refers to the detection of subclinical disease that, if left untreated, would never ...
- A Burning Questionon August 5, 2020 at 5:00 pm
Diabetes. 2005;54(4):917-927. Schmidt et al. (32) (12,330/1,335/7) White blood cell count (albumin, fibrinogen) Age, sex, center, smoking, physical activity, familial ...
- Autocrine HGF/c-Met signaling pathway confers aggressiveness in lymph node adult T-cell leukemia/lymphomaon August 3, 2020 at 5:07 pm
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasm. While ATL cells in peripheral blood (PB-ATL) are sensitive to anti-CC chemokine receptor 4 treatment, non–PB-ATLs, including ...