Can accurately detect cancer-related molecules in blood and are small enough to be used in portable medical devices
A new method that fabricates gold nanostructures quickly and efficiently could lead to highly sensitive, portable medical sensorsRecent advances in nanotechnology are providing new possibilities for medical imaging and sensing. Gold nanostructures, for example, can enhance the fluorescence of marker dyes that are commonly used to detect biomolecules and diagnose specific diseases.
Now, Ping Bai at the A*A*STAR Institute of High Performance Computing, Singapore, and co-workers have developed a fast and inexpensive way to fabricate arrays of gold nanoholes. The researchers have shown that sensor chips built using these nanostructures can accurately detect cancer-related molecules in blood and are small enough to be used in portable medical devices.
Nanohole arrays are designed so that incident light of certain wavelengths will induce large-scale oscillations of the gold electrons, known as localized surface plasmon resonance (SPR). The localized SPR focuses the absorbed light energy to enhance fluorescence (see image).
“Commercial SPR systems are already used in hospital laboratories, but they are bulky and expensive,” says Bai. “We would like to develop small, handheld devices for on-the-spot clinical use. This requires localized SPR, for which we need nanohole arrays.”
Previously, nanohole arrays have been created using electron-beam lithography (EBL), which is expensive and time consuming. Bai and co-workers used EBL to create a nickel mold and then used the mold to print nanohole patterns onto a photoresist material. The researchers made the nanostructures by evaporating gold onto the patterned structure before peeling off the photoresist material. Because the nickel mold can be reused many times, this method — called nano-imprinting — can produce large numbers of gold nanohole arrays.
The Latest on: Medical Sensors
- Wearable sensors decode dynamic sweat compositionon August 18, 2019 at 11:31 pm
A new wearable skin sensor developed at the University of California in Berkeley may be very useful to help us understand how the body’s chemical composition changes in a host of situations. For ...
- Researchers develop wearable sensors that can detect sweat rateon August 18, 2019 at 10:21 pm
The new sensors have a spiraling microscopic tube that wicks sweat ... website are for informational purposes only and not to be substituted for professional medical advice.
- Race against an ambulance shows how drones could speed up medical careon August 18, 2019 at 2:07 pm
and the Defence Science and Technology Group — were published in July in the Sensors journal. The findings made it clear that drone transport reduces delivery time and gets there quicker.
- Wireless stick-on sensors pick up physiological signals emanating from the skinon August 16, 2019 at 11:42 pm
... of sensors and receivers would be fine in medical monitoring, but to create a BodyNet that someone could wear while exercising, antennas would have to be woven into clothing to receive and ...
- Wireless sensors that stick to the skin to track our healthon August 16, 2019 at 7:39 am
One-to-one pairings of sensors and receivers would be fine in medical monitoring, but to create a BodyNet that someone could wear while exercising, antennas would have to be woven into clothing to ...
- Ethical and legal issues of ingestible electronic sensorson August 15, 2019 at 9:55 am
Ingestible electronic sensors are a promising technology for improving health ... Council Directive 93/42/EEC of 14 June 1993 concerning medical devices  OJ L169/1. 39. The Treaty on the ...
- Top 10 Sensor Companies, 2019: Discussion on Their Proprietary Technologies, Strategic Alliances, and Advantageson August 15, 2019 at 1:45 am
and Level sensors. By End-use application: automotive industry, process industry, consumer goods industry, medical field, machinery manufacturing, building construction, aircraft and ship building ...
- Factbox: Where's the fit? Sensor specialist AMS eyes lighting group Osramon August 14, 2019 at 12:02 pm
But both companies have diversified. The Austrian company says that with the acquisition it could create a global heavyweight in sensors and photonics serving the automotive, industrial and medical ...
- Vayyar Launches First Universal Sensor Solutions To Put An End to Hot Car Deathson August 14, 2019 at 7:37 am
About Vayyar Imaging Vayyar Imaging is a global leader in 4D imaging technology, providing highly advanced sensors to a wide variety of industries including automotive, smart home, robotics, retail ...
- DGAP-News: First Sensor operations on target after first half of 2019on August 13, 2019 at 11:00 pm
Demand among Asian customers for pressure sensors and photodiodes contributed to this in particular. In the Medical target market, especially the product group photonics generated growth compared ...
via Google News and Bing News