A new technique for detecting cancer by imaging the consumption of sugar with magnetic resonance imaging (MRI) has been unveiled by UCL scientists.
The breakthrough could provide a safer and simpler alternative to standard radioactive techniques and enable radiologists to image tumours in greater detail.
The new technique, called ‘glucose chemical exchange saturation transfer’ (glucoCEST), is based on the fact that tumours consume much more glucose (a type of sugar) than normal, healthy tissues in order to sustain their growth.
The researchers found that sensitising an MRI scanner to glucose uptake caused tumours to appear as bright images on MRI scans of mice.
Lead researcher Dr Simon Walker-Samuel, from the UCL Centre for Advanced Biomedical Imaging (CABI) said: “GlucoCEST uses radio waves to magnetically label glucose in the body. This can then be detected in tumours using conventional MRI techniques. The method uses an injection of normal sugar and could offer a cheap, safe alternative to existing methods for detecting tumours, which require the injection of radioactive material.”
Professor Mark Lythgoe, Director of CABI and a senior author on the study, said: “We can detect cancer using the same sugar content found in half a standard sized chocolate bar. Our research reveals a useful and cost-effective method for imaging cancers using MRI – a standard imaging technology available in many large hospitals.”
He continued: “In the future, patients could potentially be scanned in local hospitals, rather than being referred to specialist medical centres.”
The study is published in the journal Nature Medicine and trials are now underway to detect glucose in human cancers.
According to UCL’s Professor Xavier Golay, another senior author on the study: “Our cross-disciplinary research could allow vulnerable patient groups such as pregnant women and young children to be scanned more regularly, without the risks associated with a dose of radiation.”
Dr Walker-Samuel added: “We have developed a new state-of-the-art imaging technique to visualise and map the location of tumours that will hopefully enable us to assess the efficacy of novel cancer therapies.”
The Latest Bing News on:
Sugar makes cancer light-up in MRI scanners
- Deep-learning model enables rapid lymphoma detection in PET/CT imageson November 26, 2020 at 4:30 am
Madison have recently developed a deep-learning model that can perform this task automatically. This could free up valuable physician time and make quantitative PET/CT treatment monitoring possible ...
- Bone Metastases: When Cancer Spreads to the Boneson November 24, 2020 at 4:00 pm
It uses a combination of X-rays and computer technology to make cross-sectional images of the body. These images are combined into one detailed picture to show if cancer has spread to the bones. MRI .
- How tears and laughter helped us through: In truly uplifting interviews, two MPs from opposite sides of the political divide reveal the unique bond that saw them cope with ...on November 9, 2020 at 2:02 pm
When the consultant told her it was breast cancer ... scan found 'lumps' on her liver. 'I spent 24 hours crying my eyes out thinking I wouldn't see my little boy's next birthday.' An emergency MRI ...
- Why is pancreatic cancer so deadly? How to spot early signs and moreon November 9, 2020 at 6:58 am
That number rises to 97% of patients whose pancreatic cancer has spread to distant parts of the body, as in Lewis' and Trebek’s case. That makes it the lowest survival ... with imaging tests such as a ...
- The Better to See You Withon July 3, 2019 at 6:45 pm
Though the tube had an opaque covering, Röntgen noticed that whenever it was turned on, a fluorescent screen three meters away would light up ... conditions from cancer and cardiovascular disease to ...
- Brain Fog: Potential Causes and Treatmenton May 31, 2019 at 8:13 am
"One of the most common contexts that I see people come in with brain fog is chemotherapy and cancer treatments ... and lab work or conduct a CT scan or MRI of the brain," Boxley says.
- Treatment traps to avoidon March 24, 2018 at 2:49 am
The more services they provide--a blood test, surgery, an MRI or CT scan--the more money they make. Experts estimate ... transplants for advanced breast cancer. Early reports of dramatic shrinkage ...
- Primary Bone Cancer: Tests to Check the Extent of the Canceron October 21, 2017 at 1:31 pm
Cancer can look like a black hole in the white bone. A chest X-ray may also be done to see if the cancer has spread to your lungs. An MRI uses magnets ... technician during the test. A CT scan uses ...
- Doctor’s Tip: How to minimize risk in the health-care systemon June 13, 2017 at 12:12 am
If you aren’t getting better, make an appointment ... can miss the cancer). 8. If tests that involve radiation are recommended, such as CT scans or nuclear imaging, ask if there are radiation-free ...
- The Role of Imagingon May 11, 2015 at 5:28 pm
During a PET scan, a small amount of radioactive glucose (sugar) is injected into a vein. A scanner then takes detailed, computerized pictures of areas inside the body where the glucose is being used.
The Latest Google Headlines on:
Sugar makes cancer light-up in MRI scanners
The Latest Bing News on:
New technique for detecting cancer
- Multipass spectroscopy promises improved detection of cancer markers in breathon November 25, 2020 at 9:14 am
Detecting common diseases and illnesses by identifying telltale chemical compounds in exhaled breath has been a goal of biophotonics developers for several years. In the case of cancer, specific ...
- New Liquid Biopsy Method May Improve Upon Current Modalities for Early Detection of Canceron November 19, 2020 at 12:35 pm
Victor Velculescu, MD, PhD, discusses the key takeaways regarding the use of liquid biopsy to detect cancer and a new cfDNA approach to detect cancer at earlier stages.
- Israeli scientists pioneering new, less invasive breast cancer detection methodson November 17, 2020 at 8:00 am
Every day, hundreds of thousands of women worldwide get mammograms, and thousands more are sent by their doctors for biopsies to confirm or rule out the presence of breast cancer — painful, ...
- Crucial Need for Early Staging of Cancer Sets the Pace for Development of New Techniques in Breast Cancer Diagnostics Market: TMRon November 17, 2020 at 6:30 am
The drive comes from the need for early-stage cancer ... technique in the healthcare due to its cost-effectiveness. Digital mammography technologies are gathering traction due to their higher accuracy ...
- COVID-19 Creating A Cancer Crisis As Patients Delay Screenings For Early Detectionon November 17, 2020 at 1:17 am
As California and the Bay Area prepares for a worrisome new outbreak in coronavirus infections and hospitalizations, a second public health crisis has emerged: a massive drop in cancer screenings.
- New optical method paves way to breath test for cancer biomarkeron November 16, 2020 at 9:56 am
Researchers have developed an extremely sensitive, yet simple optical method for detecting formaldehyde in a person's breath. Because formaldehyde is being studied as a potential biomarker for lung ...
- Advances in Fluorescence Imaging Techniques to Detect Oral Cancer and its Precursorson November 11, 2020 at 4:00 pm
Oral cancer is a significant ... A number of new diagnostic aids to conventional oral examination have recently been introduced to assist in the early detection of oral neoplasia.
- 90% accuracy in detecting melanoma: New non-invasive methodon November 9, 2020 at 9:37 am
In Europe, melanoma is the fifth most common type of cancer and is the major cause ... 90% accuracy in detecting melanoma: New non-invasive method. ScienceDaily. Retrieved November 24, 2020 ...
- Japan researchers discover new method to detect early breast cancer smaller than 0.5 mmon November 6, 2020 at 5:06 pm
This image provided by Masayoshi Tonouchi, professor at Osaka University, shows the mechanism of a new method for detecting ... newfound technique, doctors are able to identify cancer tissues ...
- New Diagnostic Techniques for Breast Cancer Detectionon November 5, 2020 at 4:00 pm
Ductoscopy and ductal lavage is useful in investigating pathological nipple discharge, and may supplement other investigations for early detection of breast cancer. Other techniques for detection ...