Caution required for using CRISPR/Cas9 in potential gene therapies

Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells. Reported today (16 July 2018) in the

Caution required for using CRISPR/Cas9 in potential gene therapies

Electrogeochemistry can capture carbon, produce fuel, and even offset ocean acidification

Researchers analyze global potential for ‘negative emissions energy’ using electricity from renewable sources to generate hydrogen fuel and capture carbon dioxide Limiting global warming to 2 degrees Celsius will require not only reducing emissions of carbon dioxide, but also active removal of carbon dioxide from the atmosphere. This conclusion from the Intergovernmental Panel on Climate

Electrogeochemistry can capture carbon, produce fuel, and even offset ocean acidification

Reducing repetitive behavior in mice with a form of autism via CRISPR editing

Gold nanoparticles carried Cas9 enzyme into brain, editing receptor and lessening burying behavior Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder. Employing gold nanoparticles to deliver the DNA-cutting Cas9 enzyme into the brain

Reducing repetitive behavior in mice with a form of autism via CRISPR editing

Closer to finding a cure for brain diseases

A research team led by Professor Jaewon Ko and Ji Won Um from Department of Brain and Cognitive Sciences identified a new principle of formation of brain synapses through synaptic binding protein complexes. Many nerve cells that make up the brain control the function of the brain through synapses*. Although recent studies show that synaptic

Closer to finding a cure for brain diseases

A sensor that can detect dangerous mosquito-borne tropical diseases faster and at a lower cost

A startup created by Purdue University professors is developing a sensor that can detect dangerous mosquito-borne tropical diseases faster and at a lower cost than current methods, giving health officials time to take action before the viruses are transmitted to humans. SMK Diagnostics has created biosensor technology to identify and monitor diseases such as Zika, which set

A sensor that can detect dangerous mosquito-borne tropical diseases faster and at a lower cost

Predicting older adults’ risk of falling with a new wearable device

Every year, more than one in three individuals aged 65 and older will experience a fall. Falls are the most common cause of injury in older adults, and can create ongoing health problems. But treatment and awareness of falling usually happens after a fall has already occurred. As a part of the NIH’s Women’s Health Initiative,

Predicting older adults’ risk of falling with a new wearable device

Star-shaped gold nanoparticles can produce hydrogen from water over four times more efficiently

Rutgers study opens door to broader use of sunlight and advanced materials to combat climate change Star-shaped gold nanoparticles, coated with a semiconductor, can produce hydrogen from water over four times more efficiently than other methods – opening the door to improved storage of solar energy and other advances that could boost renewable energy use

Star-shaped gold nanoparticles can produce hydrogen from water over four times more efficiently

New Therapy Delays Muscle Atrophy in Lou Gehrig’s Disease Mouse Model

Mouse study could provide foundation for future human therapeutics Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig’s disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein—called mitofusion 2 or Mfn2—prevented nerve degeneration, muscle atrophy,

New Therapy Delays Muscle Atrophy in Lou Gehrig’s Disease Mouse Model

Teaching robots to be more reliable teammates for soldiers

Researchers at the U.S. Army Research Laboratory and the Robotics Institute at Carnegie Mellon University developed a new technique to quickly teach robots novel traversal behaviors with minimal human oversight. The technique allows mobile robot platforms to navigate autonomously in environments while carrying out actions a human would expect of the robot in a given

Teaching robots to be more reliable teammates for soldiers

A new approach towards the treatment of alcohol use disorder

Activating GPR139 in rats reduced excessive alcohol use and pain of withdrawal Activation of a receptor with no known function in the brain reduces excessive alcohol use and the pain of withdrawal, according to preclinical research in male rats. The study, published in eNeuro, suggests a new approach towards the treatment of alcohol use disorder.

A new approach towards the treatment of alcohol use disorder

Discovered: A protein that represents a central switching point in the aging process

Every cell and every organism ages sooner or later. But why is this so? Scientists at the German Cancer Research Center in Heidelberg have now discovered for the first time a protein that represents a central switching point in the aging process. It controls the life span of an individual – from the fly to

Discovered: A protein that represents a central switching point in the aging process

A pathway to personalized medicine and personalized biomanufacturing

Engineering cellular biology, minus the actual cell, is a growing area of interest in biotechnology and synthetic biology. It’s known as cell-free protein synthesis, or CFPS, and it has potential to provide sustainable ways to make chemicals, medicines and biomaterials. Unfortunately, a long-standing gap in cell-free systems is the ability to manufacture glycosylated proteins –

A pathway to personalized medicine and personalized biomanufacturing

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