Whitehead Institute scientists have genetically and enzymatically modified red blood cells to carry a range of valuable payloads—from drugs, to vaccines, to imaging agents—for delivery to specific sites throughout the body.
“We wanted to create high-value red cells that do more than simply carry oxygen,” says Whitehead Founding Member Harvey Lodish, who collaborated with Whitehead Member Hidde Ploegh in this pursuit. “Here we’ve laid out the technology to make mouse and human red blood cells in culture that can express what we want and potentially be used for therapeutic or diagnostic purposes.”
Lodish believes the applications are potentially vast and may include RBCs modified to bind and remove bad cholesterol from the bloodstream, carry clot-busting proteins to treat ischemic strokes or deep-vein thrombosis, or deliver anti-inflammatory antibodies to alleviate chronic inflammation.
Read more . . .
The Latest on: Engineered Red Blood Cells
[google_news title=”” keyword=”Engineered Red Blood Cells” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Engineered Red Blood Cells
- Abu Dhabi Stem Cells Center partners with Red Crescent to enhance bone marrow transplant accessibility for patientson April 18, 2024 at 2:59 am
Abu Dhabi: Abu Dhabi Stem Cells Center (ADSCC) has partnered with Emirates Red Crescent (ERC) to enhance accessibility to bone marrow transplants for patients in need, providing them with treatment ...
- MIT Technology Reviewon April 12, 2024 at 3:00 am
CAR-T cells could revolutionize the treatment of a wide variety of diseases, if only we can make them cheaper.
- Clinical trial: Some sarcoma patients improve with T cell immunotherapyon March 28, 2024 at 8:33 am
The most common side effects of the treatment involved low red and white blood cell counts due to the chemotherapy needed to prepare the body to receive the engineered T cells. Many of the ...
- Blood, sweat, and water: New paper analytical devices easily track health and environmenton March 27, 2024 at 5:01 pm
When you need to measure white blood cell counts, it usually involves trips ... in which the paper is engineered with channels and collection zones that measure out defined volumes of blood ...
- What to Expect When Starting CAR T-Cell Therapy for Multiple Myelomaon March 24, 2024 at 5:00 pm
White blood cells are extracted from the blood and genetically engineered in a lab to create “personalized” medication, which is then given by infusion. “Myeloma CAR T-cell therapy has shown ...
- Cannibal Cells Inspire Cancer Treatment Improvementon March 18, 2024 at 5:00 pm
This “cellular cannibalism” is a common natural process: within your own body, white blood cells are consuming millions of old red blood cells ... where the engineered cells should hunt ...
- Researchers identify enzyme key to training cells to fight autoimmune disorderson February 27, 2024 at 1:12 pm
Without these bone marrow stem cells, the body can't make white blood cells to fight infections, red blood cells to carry ... This mouse model has been engineered with Th1 cells that cause ...
- How personalized medicine is transforming your health careon October 4, 2023 at 8:52 am
micro-engineered spinal cord tissue from a patient with amyotrophic lateral sclerosis. Motor neurons (white) and a blood vessel (red), derived from the ALS patient’s stem cells, form functioning ...
- Red Light Therapy Offers a Slew of Unexpected Health Benefits, From Healing Cold Sores to Reducing Wrinkleson April 22, 2023 at 2:21 pm
The authors of thousands of published peer-reviewed papers believe that this band of light stimulates the mitochondria in your cells ... s Red Light Therapy Sleep Light is engineered to help ...
- Red Cell Therapeutics: realizing the promise of cellular medicineon March 1, 2022 at 6:05 am
Rubius Therapeutics is a biopharmaceutical company based in Cambridge, Massachusetts, USA, that is developing allogeneic cell therapies based on biologically engineered red blood cells (RBCs).
via Bing News