A James Cook University scientist is part of an international team that’s used new ‘big data’ analysis to achieve a major advance in understanding neurological disorders such as Epilepsy, Alzheimer’s and Parkinson’s disease.
Dr Ashley Waardenberg, a Theme Leader from JCU’s Centre for Tropical Bioinformatics and Molecular Biology, said scientists from JCU, The Children’s Medical Research Institute, Sydney, University of Southern Denmark and Bonn University (Germany) looked at how neurons in the brain communicated with each other.
“We studied the synapse – the communication hotspot between neurons – which is a place where neurological disorders and diseases can interfere with the brain’s normal functions,” said Dr Waardenberg.
“We aimed to use new methods for mapping the protein pathways that neurons use to communicate with each other (neurotransmission) and tried to see if we could identify patterns of activity related to memory.”
“A key part of the project that I led was to develop new computational methods to assess the very large amount of data that we collected. This led to the discovery of the major proteins responsible for the changes observed in the neurons,” said Dr Waardenberg.
He said the discoveries open up many new avenues for studying the protein pathways underlying neurotransmission and how they might be linked to neurological diseases and disorders.
Dr Waardenberg said the breakthrough demonstrates how new computational methods are needed to develop insights from ‘big data’.
He said the team of scientists is releasing the paper detailing the computational methods and the thousands of new proteins sites identified as a resource to the scientific community.
“We hope that this resource will help our future understanding of neuron signaling and memory. The discovery has very important implications for understanding the mechanisms of neurotransmission and neurological disorders,” he said.
Dr Waardenberg is now aiming to establish these new methods at JCU and continue to develop new computational methods for tackling tropical diseases such as malaria.
Learn more: Big data takes aim at a big human problem
The Latest on: Big data
via Google News
The Latest on: Big data
Executive Voice: He used big data to help warfighters. Now, he’s innovating Colorado’s health-care industry.
on March 22, 2019 at 6:38 am
Armed with an expertise in Air Force space and missile defense and helping warfighters make critical decisions, Centura Health’s newest executive hire may not seem like your typical health-care ... […]
How Big Data Has Impacted The Real Estate Industry
on March 22, 2019 at 6:05 am
Big data has made its way into virtually every industry. The real estate profession is no exception. Real estate professionals all over the world are benefiting from big data in a number of ways. CIO ... […]
Big Data Analytics in Healthcare Market Seeing 19.1% CAGR to 2025
on March 22, 2019 at 5:01 am
Portland, OR, March 22, 2019 (GLOBE NEWSWIRE) -- According to this latest research study, titled, "Big Data Analytics in Healthcare Market by Component, Deployment, Analytics Type, Application, and ... […]
Big data: seeing investments in an entirely new way
on March 21, 2019 at 9:04 pm
Across American society, big data is shining a brilliant light on previously obscure relationships. Marketers use people's web searches and purchase histories to offer up their most irresistible ... […]
Be Prepared: Big Data is Taking Over Your Life
on March 21, 2019 at 1:55 pm
Something big is about to take place by next year. Every second about 1.7 megabytes of new information will be created about you and every other human being on the planet, experts predict. This ... […]
Big-data software firm Tresata's upcoming hackathon to tackle public health
on March 21, 2019 at 12:52 pm
It's the seventh year for Tresata Inc.'s annual hackathonCLT — an opportunity for technology experts to spend 24 hours tackling some of Charlotte's toughest issues. Organizers expect this year's event ... […]
3 Essential Big Data Security Protocols To Be Aware Of
on March 21, 2019 at 11:55 am
The way that we do business today is way different than the way we were doing business 20 years ago before the modern age hit us like a sack of bricks. Now, we live in a modernized world where big ... […]
When Big Data and Cybersecurity Collide
on March 21, 2019 at 9:13 am
The rise of big data and the evolution of cybersecurity are intertwined in important ways. Understanding how they relate can help companies better determine what capabilities they must develop or ... […]
Big data and machine learning: The perfect ingredients for cybersecurity
on March 20, 2019 at 8:34 am
Protecting your business against hackers who are developing increasingly sophisticated strategies to bypass your security is growing even more challenging today. Cyber threats are continually ... […]
Big data takes on cancer
on March 20, 2019 at 7:48 am
Regina Barzilay wasn’t looking to study cancer. She had made a name for herself as an artificial intelligence (AI) researcher at the Massachusetts Institute of Technology (MIT) in Cambridge, ... […]
via Bing News