A James Cook University scientist is part of an international team that’s used new ‘big data’ analysis to achieve a major advance in understanding neurological disorders such as Epilepsy, Alzheimer’s and Parkinson’s disease.
Dr Ashley Waardenberg, a Theme Leader from JCU’s Centre for Tropical Bioinformatics and Molecular Biology, said scientists from JCU, The Children’s Medical Research Institute, Sydney, University of Southern Denmark and Bonn University (Germany) looked at how neurons in the brain communicated with each other.
“We studied the synapse – the communication hotspot between neurons – which is a place where neurological disorders and diseases can interfere with the brain’s normal functions,” said Dr Waardenberg.
“We aimed to use new methods for mapping the protein pathways that neurons use to communicate with each other (neurotransmission) and tried to see if we could identify patterns of activity related to memory.”
“A key part of the project that I led was to develop new computational methods to assess the very large amount of data that we collected. This led to the discovery of the major proteins responsible for the changes observed in the neurons,” said Dr Waardenberg.
He said the discoveries open up many new avenues for studying the protein pathways underlying neurotransmission and how they might be linked to neurological diseases and disorders.
Dr Waardenberg said the breakthrough demonstrates how new computational methods are needed to develop insights from ‘big data’.
He said the team of scientists is releasing the paper detailing the computational methods and the thousands of new proteins sites identified as a resource to the scientific community.
“We hope that this resource will help our future understanding of neuron signaling and memory. The discovery has very important implications for understanding the mechanisms of neurotransmission and neurological disorders,” he said.
Dr Waardenberg is now aiming to establish these new methods at JCU and continue to develop new computational methods for tackling tropical diseases such as malaria.
Learn more: Big data takes aim at a big human problem
The Latest on: Big data
via Google News
The Latest on: Big data
- Esri Ireland’s Eamonn Doyle: ‘Big data is creating a new era for mapping’ on March 15, 2019 at 8:41 am
Esri Ireland’s Eamonn Doyle believes that a combination of big data and IoT means organisations can sense things in a way that was hitherto impossible. Eamonn Doyle is CTO of Esri Ireland, which is ... […]
- Tips for using big data to measure pension longevity risk on March 15, 2019 at 7:39 am
While estimating the longevity of a pension plan’s membership isn’t a new concept, developments in using big data and new tools in predictive modelling could go a long way to making predictions more ... […]
- Adaptive learning system using big data based machine learning on March 15, 2019 at 7:09 am
Over the past few decades, many studies conducted in the field of learning science have reported that scaffolding plays an important role in human learning. To scaffold a learner efficiently, a ... […]
- Insurance Companies are Using Big Data Analytics, know how on March 15, 2019 at 4:11 am
The Internet has become the most potent source of information in recent years. It has brought all the information at a person’s fingertips. Businesses are also leveraging this innovative solution to ... […]
- Is Big Data The Key To Our Culture’s Relationship Crisis? on March 15, 2019 at 3:15 am
Big data is solving countless challenges in the business world. One of the biggest benefits of big data is improving relationship building. Victoria Greene, a writer for Bloomberg, wrote about the ... […]
- The economic data that moves the Australian dollar the most, according to big data on March 14, 2019 at 6:03 pm
The Australian dollar is among the most traded currencies around the world. Researchers at the Commonwealth Bank have used big data to uncover what major data releases tend to move the AUD/USD the ... […]
- Scaleworks portfolio startup hires new CEO for big data on March 14, 2019 at 12:00 pm
More than two years after Scaleworks Associates acquired Silicon Valley technology startup Keen, it has tapped a local executive as its CEO. Ben Kuhn, who moved to San Antonio from Denver in 2016, is ... […]
- Redis Labs Recognized as a Leader in Independent Analyst Report on Big Data NoSQL Platforms on March 14, 2019 at 10:30 am
MOUNTAIN VIEW, Calif., March 14, 2019 /PRNewswire/ -- Redis Labs, the home of Redis and provider of Redis Enterprise, today announced it has been named a Leader in Big Data NoSQL platforms by ... […]
- Evaluate Big Data with These Five Qualities on March 14, 2019 at 9:44 am
Big data can span galaxies. Source: NASA JPL. One of the top buzzwords of the last decade of business has to be “big data.” The term has escaped Silicon Valley and now rears its head ... […]
- Big-data firm Cloudera crashes on lower earnings and guidance on March 13, 2019 at 8:24 pm
Big-data company Cloudera Inc. saw its stock take a beating late Wednesday after posting a wider-than-expected loss for the quarter just gone. The company, which sells software based on Apache ... […]
via Bing News