A new method to diagnose cancer cells inside lymph nodes could allow doctors to treat cancers before they spread around the body.
The vast majority of cancer deaths occur due to the spread of cancer from one organ to another, which can happen either through the blood or the lymphatic system. However, it can be tricky to detect this early enough. Researchers at Tohoku University have developed a new method that would allow doctors to detect cancers in the lymph nodes while they are still small, before they travel to other parts of the body. This can greatly increase the chances of a successful treatment.
There aren’t many imaging techniques that can detect tumors in lymph nodes before they grow too large, especially in smaller nodes. Biopsies of lymph nodes is a possible option, but it can often give false negative results. So the team wanted to come up with a new method that would accurately detect the earliest stages of a cancer moving to another part of the body, using a technique called x-ray microcomputed tomography (micro-CT).
The team tested their new method on mice with breast cancer cells inserted into their lymph nodes. They injected a contrast agent at a slow, steady pace into the lymph nodes upstream of those carrying the cancer cells. As the contrast agent made its way through the lymphatic system, the researchers were able to map out its movement using micro-CT.
Initially, the researchers did not observe any change in the flow of the contrast agent. However, after 28 days of injecting the cancer cells into the lymph nodes, they had divided and grown to a point where they blocked the flow of the contrast agent, creating empty pockets in the scan that did not have any contrast agent.
By comparing the shape of the lymph node and the areas that contained the contrast agent, the researchers were able to get a clear picture of the presence of cancer cells there.
Next, the researchers would like to hone in on better contrast agents that would offer a clearer, more precise picture of how cancer cells are moving around the lymphatic system. In the future, this technique could be an effective way to detect tumors early before they spread around the body, saving many lives and adding one more tool that doctors can turn to in their fight against cancer.
The Latest on: Micro-CT
via Google News
The Latest on: Micro-CT
- The September edition of The Bridge, the Materials Science newsletter from Rigaku, is onlineon September 30, 2020 at 1:55 am
Also featured is the Rigaku CT Lab HX high-performance benchtop X-ray micro-CT system. It has the most powerful X-ray source in its class (130 kV, 39 W) and the advantage of a small footprint with low ...
- A tiny crustacean fossil contains roughly 100-million-year-old giant spermon September 25, 2020 at 5:02 am
Using micro-CT scans, Dave Horne, a micropaleontologist at Queen Mary University of London, and colleagues peered inside a few of the tiny shelled animals. “We knew from looking at the piece of ...
- Viewing flattened fossils in a new lighton September 18, 2020 at 7:50 am
That is what Ortega-Hernández has been doing during the last five years in conjunction with Yu Liu, a paleobiology professor at Yunnan University in China, using micro-CT. The method is basically a ...
- OEB Professor Ortega-Hernández Discovers Ancient Arthropod Specieson September 16, 2020 at 8:34 pm
The species, however, was quite small in length, measuring 2 centimeters. Through micro-CT imaging, the researchers were also able to determine that the shrimp-like creature had a boomerang-shaped ...
- Dinganthus sheds new light on evolution of flowerson September 14, 2020 at 8:09 am
The good preservation and modern observation technology (Micro-CT) allow the key features of the flower to be clearly demonstrated. The flower includes bracts, tepals, stamens, and gynoecium.
- Ancient Egypt: Mummified animals 'digitally unwrapped' in 3D scanson August 19, 2020 at 5:00 pm
Researchers said the details revealed by the scans were "extraordinary". Using micro CT scanners, which generate 3D images with 100 times the resolution of medical CT scans, the animals' remains ...
- Micro-CT and X-ray Microscopy Imaging Facilityon August 19, 2020 at 5:00 pm
Micro-computed tomography (μCT) is a three-dimensional, X-ray-based imaging modality that can image tissues, organs and whole organisms as well as nonorganic structures with a spatial resolution as ...
- Micro CT Scannerson August 13, 2020 at 10:50 pm
Once submitted, we will try and place you in contact with a suitable Micro-CT Scanners supplier within 48 hours.
- Nikon Metrology HMX ST 225on August 12, 2019 at 5:50 am
The Nikon Metrology HMX ST 225 is a versatile micro-CT scanner that can image specimens from 0.5-20 centimetres in diameter with a maximum resolution of five micrometres. It can produce a maximum ...
- Zeiss Xradia Versa 520on June 25, 2019 at 1:07 pm
The Carl Zeiss Xradia Versa 520 is a high resolution micro-CT scanner that can image specimens from 150µm to 3cm in diameter. Under certain scanning conditions the machine can achieve a resolution of ...
via Bing News