A new study by Waldemar Gorski, professor and chair of the UTSA Department of Chemistry, and Stanton McHardy, associate professor of research in chemistry and director of the UTSA Center for Innovative Drug Discovery, describes a method that could show quickly and accurately whether a person has been infected with harmful bacteria or other pathogens. Additionally, this new method shows the exact severity of infection in a person.
The most common method of testing for infection in medical facilities is a strip that turns a certain color when infected fluids come into contact with it.
“The problem with this method is that it’s imprecise,” Gorski said. “The human eye is forced to judge the level of infection based on the hue and deepness of a color. It’s difficult to make an accurate call based on that.” Furthermore, roughly a third of samples cannot be tested because the fluids contain blood or are too opaque.
Other methods include microbiology or examining body fluid samples under a microscope and counting white blood cells, also known as leukocytes, which are an indicator of an infection. However, these can be slow processes and require more highly trained personnel.
Gorski, seeing a need for an easier and more rapid method of testing for infection, resolved to test an electrochemical approach, and sought out McHardy, a medicinal chemist. Together, they created molecules that bind to leukocyte enzymes and produce an electrical current to signal the presence of an infection.
Their new molecules are housed on a testing strip. After being contacted with infected bodily fluids, the strip is connected to a computer monitor that displays a clear range of electrochemical responses demonstrating the severity of an infection.
“The signs and symptoms people demonstrate aren’t always reflective of the level of the infection they have,” McHardy said. “This method could very easily show just how serious an infection is and make diagnosis a much quicker process, possibly preventing a more serious illness.”
Gorski believes the method could be especially useful to people who have just undergone surgery, as it could determine definitively whether they have an infection from the procedure before it worsens.
Receive an email update when we add a new INFECTIONS article.
The Latest on: Detecting infections
via Google News
The Latest on: Detecting infections
- Machine-learning can be used to predict risk of fatal infection from hospital bug: Research on December 16, 2018 at 10:26 pm
This can have a big impact in reducing the burden of such infections by high-risk bacteria. Machine learning and AI is being increasingly used to highlight health risks. Recently, Google announced tha... […]
- India drafts first national essential diagnostics list; vector-borne diseases, NCDs given high on December 16, 2018 at 6:30 pm
India has drafted the first national essential diagnostics list (NEDL), a country-specific set of tests for detecting common morbid conditions and priority diseases, along the lines of the National Li... […]
- Detecting Work-related Diseases Using Alert and Sentinel Systems: New Research on December 14, 2018 at 8:17 am
A new report details the findings of a major project in which the European Agency for Safety and Health at Work (EU-OSHA) brought together experts and policy-makers from across Europe to examine ... […]
- AI, microscopic imaging mobile device detects parasitic infections in 20 minutes on December 13, 2018 at 1:53 pm
The diagnosis of parasitic infections may become a more widely available and ... The new platform—which can detect motile parasites in bodily fluids automatically, and analyze more than three millilit... […]
- Duct Diseases You Can Cure on December 13, 2018 at 12:13 pm
We are the world’s only hope to eradicate duct diseases. Let’s take a look at the most devastating duct diseases, how to detect their symptoms, prescribe a cure, and perform the required surgery to re... […]
- Smart Tattoos to Detect Fever, Sun Exposure, and Maybe Diagnose Diseases on December 13, 2018 at 10:51 am
Tattoos have a long history on the human skin, underlined by a find of a body in the Alps more than 5,000 years old that had tattoos all over it. While tattoos have mostly served as decorations, statu... […]
- Mobile device makes the detection of parasitic infections faster and more sensitive using artificial intelligence on December 13, 2018 at 7:11 am
Parasitic infections affect hundreds of millions of ... developed an inexpensive and portable platform that can rapidly detect motile parasites in bodily fluids automatically. […]
- Newly Published Case Series Demonstrates the Karius Test's Effectiveness for Monitoring Infections in Stem-Cell Transplant Pa... on December 13, 2018 at 4:07 am
The early findings showed that the Karius® Test, a non-invasive blood test that detects pathogen cell-free DNA in plasma, is an effective infectious disease diagnostic that can quickly and accurately ... […]
- UAlberta scientists identify biomarkers for detecting Alzheimer's disease in saliva samples on December 13, 2018 at 12:06 am
A saliva test would prove useful in clinical settings for its ease and non-invasive nature. It also has the potential to detect neurodegenerative diseases earlier on, allowing for early intervention. ... […]
via Bing News