Chemists have modified the enzyme levansucrase using a new method. The enzyme can now produce sugar polymers that are exciting for applications in the food industry and medicine.
Enzymes are tools of nature that accelerate almost all biochemical reactions in living cells as biological catalysts. For this reason, enzymes have been used in the chemical industry for some time now – in detergents and cleaners, toothpastes and shampoos, but also in foods. Enzymes help in the production of paper, textiles, leather, medicines, biofuels and other products.
Enzymes from the tailoring industry
Biochemically, enzymes are proteins that are composed of natural amino acids. They form a three-dimensional structure. Just like a key fits into a lock, each specific molecule fits into an enzyme and the enzyme converts it into a new product.
Technically, it is possible to exchange individual amino acids in an enzyme and thereby change its structure so that it can now process other molecules. In this way, British scientists have created just recently a mutant enzyme that breaks down plastic.
Surface of the levansucrase changed
Chemists from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany, have now gone a step further in the tailoring of enzymes: “We thought what fascinating possibilities would arise if we could change the surface of enzymes chemically and use the chemical space of molecules,” says Jürgen Seibel , Professor of Organic Chemistry at the JMU. “We have developed a reaction that does not occur in nature in this way. It gives us a lot of freedom in reshaping enzyme surfaces. “
As the JMU scientists report in the journal “Chemical Science”, they first redesigned the surface of the enzyme levansucrase. Now, the enzyme can convert the table sugar (sucrose) directly into a polymer of fructose building blocks.
“So far, such a synthesis has been possible with levansucrase, but it works much more efficiently with the modified enzyme,” explains Seibel. The conversion of the enzyme per second is now significantly higher; moreover, it mainly produces the desired product and no accidental by-products.
Interesting for medicine and food industry
The fructose polymer could be used as a bio-gel for tissue transplantation in medicine or in the food industry – for example as a probiotic supplement in yogurts or baby food. Because like other functional sugars, the polymer could also serve certain intestinal bacteria as food and indirectly exert a health-promoting influence on the intestinal flora of humans.
Learn more: New technology for enzyme design
The Latest on: Enzyme design
via Google News
The Latest on: Enzyme design
- Global Packaging Coating Additives Market 2018-2023 on October 5, 2018 at 10:10 am
The "Packaging Coating Additives Market by Function (Slip, Anti-Static, Anti-fog, Anti-block, etc.), Formulation (Water-based, Solvent-based, Powder-based), Application (Food, Industrial ... […]
- Offshore Guyana Pipe Coating Contracts Go to Shawcor on October 5, 2018 at 8:54 am
Shawcor to provide thermal insulation and anticorrosion pipe coating services. Saipem has awarded Shawcor Ltd.’s pipe coating division contracts to provide pipe coating services for the Liza phases I ... […]
- North America Powder Coating Market to 2025 - Companies Taking Strategic Decision To Gain Market Presence on October 5, 2018 at 8:14 am
The "North America Powder Coating Market: Companies Profiles, Size, Share, Growth, Trends and Forecast to 2025" report has been added to ResearchAndMarkets.com's offering. North America powder ... […]
- Optical Coating Machines Industry report with market analysis detailed in new research report on October 5, 2018 at 8:02 am
Global Optical Coating Machines Sales Market Research Report 2018 contains historic data that spans 2013 to 2016, and then continues to forecast to 2025. That makes this report so invaluable, resource... […]
- Dreary coating of lichen being scrubbed from state Capitol on October 4, 2018 at 3:55 pm
The Capitol dome — and the rest of the Legislative Building — are getting a much-needed cleaning. During the 2018 legislative session, the Legislature approved $3.4 million for masonry preservation wo... […]
- North America Powder Coating Market 2018-2025: Companies Profiles, Size, Share, Growth, Trends and Forecasts - ResearchAndMarkets.com on October 4, 2018 at 10:17 am
The "North America Powder Coating Market: Companies Profiles, Size, Share, Growth, Trends and Forecast to 2025" report has been added to ResearchAndMarkets.com's offering. North America powder coating ... […]
- The Global Conformal Coating Market is Likely to Hit USD 16 billion by 2024 | Hexa Research on October 4, 2018 at 7:28 am
"Fact-based market research, penetrating industry insights and validated forecasts to help you make better decisions for a stronger future" Research Report on Conformal Coating Market Analysis, Market ... […]
- Seco Introduces Jabro-HFM JHF181 End Mills with HXT Coating on October 4, 2018 at 5:05 am
The Jabro®-HFM JHF181 Solid-Carbide End Mills is offered in 2-, 4- or 5-flute options with diameters ranging from 2 mm to 16 mm and lengths between 2xD and 7xD. The units are suitable for high-speed m... […]
- How to Evaluate a CVD Coating? on October 4, 2018 at 3:55 am
The ability to characterize the surface of a material is an important part of SilcoTek’s coating research and development. In order to understand new inert coatings the surface must be thoroughly char... […]
via Bing News