Research led by Suresh Alahari, PhD, Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has demonstrated the potential of a protein to treat or prevent metabolic diseases including obesity and diabetes.
The findings are published online in the Journal of Biological Chemistry as a Paper in Press, available here. Nischarin is a novel protein discovered by the Alahari lab. The research team demonstrated that it functions as a molecular scaffold that holds and interacts with several protein partners in a number of biological processes. The lab’s earlier research found that Nischarin acts as a tumor suppressor that may inhibit the spread, or metastasis, of breast and other cancers.
“These studies demonstrate the potential of Nischarin as a regulator of metabolic diseases and suggest suppression of Nischarin function may be a valuable approach in the quest to cure such diseases as diabetes and obesity,” notes Dr. Alahari.According to the National Health and Nutrition Examination Survey (NHANES), 2013–2014, more than 2 in 3 US adults (70.2 percent) were considered to be overweight or obese. The American Diabetes Association says that in 2015, 30.3 million Americans, or 9.4% of the population, had diabetes.
The Latest on: Nischarin
- LSU researchers make discovery with potential to cure obesity, diabetes on September 12, 2017 at 6:06 pm
The discovery came as an accident when researchers were studying the gene, Nischarin, for its other benefits. Researchers said the gene acts as a tumor suppressor that may inhibit the spread, or metastasis, of breast and other cancers. But while deleting ... […]
- Chancellor of Nunez Community College announces retirement, and other news of higher education on September 3, 2017 at 11:45 am
Alahari's lab demonstrated that the novel protein Nischarin functions as a molecular scaffold that holds and interacts with several protein partners in a number of biological processes. The lab’s earlier research found that Nischarin acts as a tumor ... […]
- IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells on June 17, 2017 at 1:14 pm
Correspondence: M Dontenwill, Pharmacologie et Physicochimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Faculté de Pharmacie, Université Louis Pasteur de Strasbourg, Illkirch, France. Tel: +33 3 90244267; Fax: +33 3 90244313; E-mail ... […]
via Google News and Bing News