Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionise the treatment of one of the leading causes of blindness in the UK.
The results of the collaborative research, published today in Investigative Opthamology and Visual Science, could spell the end of painful injections directly into the eye to treat the increasingly common eye disorder known as age-related macular degeneration (AMD).
AMD affects more than 600,000 people in the UK and predictions suggest this figure could rise sharply in future because of an ageing population.
A painless condition which causes people to gradually lose their central vision, usually in both eyes, AMD is currently treated by repeated injections into the eye on a monthly basis over at least three years.
This is a problem because, apart from being an unpleasant procedure for patients to undergo, the injections can cause tearing and infections inside the eye and an increased risk of blindness.
Now scientists led by biochemist Dr Felicity de Cogan, from the University of Birmingham’s Institute of Inflammation and Ageing, have invented a method of delivering the injected drug as an eye drop instead, and their laboratory research has obtained the same outcomes as the injected drug.
The drop uses a cell-penetrating peptide (CPP) to deliver the drug to the relevant part of the eye within minutes.
Dr de Cogan said: “The CPP-drug has the potential to have a significant impact on the treatment of AMD by revolutionising drug-delivery options.
“Efficacious self-administered drug application by eye drop would lead to a significant reduction in adverse outcomes and health care costs compared with current treatments.
“The CPP-plus drug complex also has potential application to other chronic ocular diseases that require drug delivery to the posterior chamber of the eye.
“We believe this is going to be very important in terms of empowering of patients and reducing the cost of treatment to the NHS.”
The Latest on: Age-related macular degeneration
- Do carrots really improve your vision? on August 19, 2017 at 3:00 am
Other studies have shown that certain nutrients within carrots can make a difference among older adults with age-related macular degeneration. Harvard Health Publications put out an article on the topic and it explained, “Carrots are one of several ... […]
- Health Beat: Preventing age-related macular degeneration on August 17, 2017 at 2:09 pm
PHOENIX - Howard Morrow enjoys days with his wife, Joyce, and dog, Oliver, but his age-related macular degeneration, or AMD, has progressed to the more serious "wet" form. Now, he gets injections to slow the disease. "It's a big pain once a month to get in ... […]
- Macular Degeneration (AMD) and Diabetic Retinopathy (DR) Drugs Market to Discern Steadfast Expansion During 2015 - 2021 on August 16, 2017 at 9:59 pm
Age related macular degeneration (AMD) is a medical condition that results in loss of vision in the central visual field, owing to damage to the retina. This is usually an age-related disorder, which affects adults with the age 50 and above. Diabetic ... […]
- What Is Macular Degeneration? on August 16, 2017 at 8:22 pm
Another common age-related condition is macular degeneration, a disease that affects more than 10 million Americans, and, according to the National Eye Institute is the leading cause of vision loss among people over 50. Still, despite its prevalence ... […]
- New Anti-VEGF Drug Promising for Wet Macular Degeneration on August 15, 2017 at 11:27 am
BOSTON — A new antivascular endothelial growth-factor (VEGF) drug, OPT-302 (Opthea), appears to be safe and shows signs of effectiveness in the treatment of neovascular age-related macular degeneration, new research shows. The experimental drug could ... […]
via Google News and Bing News