May 162017

via University of Birmingham

Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionise the treatment of one of the leading causes of blindness in the UK.

The results of the collaborative research, published today in Investigative Opthamology and Visual Science, could spell the end of painful injections directly into the eye to treat the increasingly common eye disorder known as age-related macular degeneration (AMD).

AMD affects more than 600,000 people in the UK and predictions suggest this figure could rise sharply in future because of an ageing population.

A painless condition which causes people to gradually lose their central vision, usually in both eyes, AMD is currently treated by repeated injections into the eye on a monthly basis over at least three years.

This is a problem because, apart from being an unpleasant procedure for patients to undergo, the injections can cause tearing and infections inside the eye and an increased risk of blindness.

Now scientists led by biochemist Dr Felicity de Cogan, from the University of Birmingham’s Institute of Inflammation and Ageing, have invented a method of delivering the injected drug as an eye drop instead, and their laboratory research has obtained the same outcomes as the injected drug.

The drop uses a cell-penetrating peptide (CPP) to deliver the drug to the relevant part of the eye within minutes.
Dr de Cogan said: “The CPP-drug has the potential to have a significant impact on the treatment of AMD by revolutionising drug-delivery options.

“Efficacious self-administered drug application by eye drop would lead to a significant reduction in adverse outcomes and health care costs compared with current treatments.

“The CPP-plus drug complex also has potential application to other chronic ocular diseases that require drug delivery to the posterior chamber of the eye.

“We believe this is going to be very important in terms of empowering of patients and reducing the cost of treatment to the NHS.”

Learn more: University of Birmingham develops revolutionary eye drops to treat age-related blindness


The Latest on: Age-related macular degeneration
  • New Research released with alarming findings
    on May 22, 2017 at 7:42 am

    However, they could be letting themselves down by not investing time in their own eye health.” Macular Degeneration is an age-related disease with one in seven Australians over 50 having some evidence of it. People with a family history of Macular ... […]

  • Best of Last Week – Using stars as random number generator, Antarctica greening and eye drops treat macular degeneration
    on May 22, 2017 at 5:31 am

    And finally, if you are one of the millions around the world suffering vision loss due to macular degeneration ... that they had developed revolutionary eye drops to treat age-related blindness—it is based on a cell-penetrating peptide that is able ... […]

  • New treatment method for age-related macular degeneration
    on May 22, 2017 at 3:02 am

    The leading cause of vision loss in people over 50 is a condition called age-related macular degeneration (AMD). As the name suggests, the main reason for developing this condition is simply growing older. AMD often results in loss of central vision in ... […]

  • Macular degeneration week puts eyes in focus
    on May 22, 2017 at 1:49 am

    This week is Macular Degeneration Week. It is an age-related disease with one in seven people over 50 having evidence of it. People with a family history have a 50 per cent chance of developing the disease. Macular Disease Foundation Tasmania chair Nitin ... […]

  • Understanding the risk factors for macular degeneration
    on May 20, 2017 at 5:30 am

    Q: I was recently diagnosed with wet macular degeneration and am now receiving periodic injections for the disease. What causes it? Are there any risk factors, such as drugs or diet? A: Age-related macular degeneration (AMD) is the leading cause of adult ... […]

via Google News and Bing News

Other Interesting Posts

Leave a Reply

%d bloggers like this: