Tiny magnetic particles from air pollution have for the first time been discovered to be lodged in human brains– and researchers think they could be a possible cause of Alzheimer’s disease.
Researchers at Lancaster University found abundant magnetite nanoparticles in the brain tissue from 37 individuals aged three to 92-years-old who lived in Mexico City and Manchester. This strongly magnetic mineral is toxic and has been implicated in the production of reactive oxygen species (free radicals) in the human brain, which are associated with neurodegenerative diseases including Alzheimer’s disease.
Professor Barbara Maher, from Lancaster Environment Centre, and colleagues (from Oxford, Glasgow, Manchester and Mexico City) used spectroscopic analysis to identify the particles as magnetite. Unlike angular magnetite particles that are believed to form naturally within the brain, most of the observed particles were spherical, with diameters up to 150 nm, some with fused surfaces, all characteristic of high-temperature formation – such as from vehicle (particularly diesel) engines or open fires.
The spherical particles are often accompanied by nanoparticles containing other metals, such as platinum, nickel, and cobalt.
Professor Maher said: “The particles we found are strikingly similar to the magnetite nanospheres that are abundant in the airborne pollution found in urban settings, especially next to busy roads, and which are formed by combustion or frictional heating from vehicle engines or brakes.”
Other sources of magnetite nanoparticles include open fires and poorly sealed stoves within homes. Particles smaller than 200 nm are small enough to enter the brain directly through the olfactory nerve after breathing air pollution through the nose.
“Our results indicate that magnetite nanoparticles in the atmosphere can enter the human brain, where they might pose a risk to human health, including conditions such as Alzheimer’s disease,” added Professor Maher.
Leading Alzheimer’s researcher Professor David Allsop, of Lancaster University’s Faculty of Health and Medicine, said: “This finding opens up a whole new avenue for research into a possible environmental risk factor for a range of different brain diseases.”
The Latest on: Magnetite nanoparticles
via Google News
The Latest on: Magnetite nanoparticles
- What happens to magnetic nanoparticles once in cells? on February 18, 2019 at 2:55 pm
Although magnetic nanoparticles are being used more and more in cell imaging and tissue bioengineering, what happens to them within stem cells in the long term remained undocumented. Researchers have ... […]
- MRI Guided Drug Delivery Market Size, Industry Status and Forecast 2018-2028 on February 18, 2019 at 9:13 am
MRI guided drug delivery or magnetic resonance guided drug delivery is a part ... The MRI guided delivery system uses multifunctional super-paramagnetic iron oxide (SPIO)-based nanoparticles as a nano ... […]
- Regaining Heart Function With Transplanted Muscle Cells on February 18, 2019 at 12:44 am
Heart attack survivors may find some relief from the efforts of University of Bonn researchers who have exhibited a procedure to repair cardiac tissue after a heart attack using replacement muscle cel... […]
- Spintronics by ‘straintronics’ on February 15, 2019 at 10:33 am
“This lets us hope that the phenomenon can be used for the design of new composite materials (consisting of ferroelectric and magnetic nanoparticles) for low-power spin-based storage and logic archite... […]
- Spintronics by 'straintronics': Switching superferromagnetism with electric-field induced strain on February 15, 2019 at 5:12 am
"This lets us hope that the phenomenon can be used for the design of new composite materials (consisting of ferroelectric and magnetic nanoparticles) for low-power spin-based storage and logic ... […]
- New research explains presence of ‘natural’ magnetism in human cells on February 13, 2019 at 8:32 pm
Although magnetic nanoparticles are being used more and more in cell imaging and tissue bioengineering, what happens to them within stem cells in the long term remained undocumented. Researchers from ... […]
- What happens to magnetic nanoparticles in cells? on February 13, 2019 at 6:04 am
Synthesis of magnetic nanoparticles within stem cells, starting from the degradation product from previously internalized nanoparticles. These biosynthesized nanoparticles are produced in situ ... […]
- What are Nanoceramics and Their Applications on February 11, 2019 at 5:15 am
Nanoceramics are a type of nanoparticle first discovered in the early 1980s composed ... Nanoceramics possess their own chemical, physical, mechanical and magnetic properties that differ from other ma... […]
- Momentous CRISPR-enabled developments on February 7, 2019 at 8:09 am
Via complexation of the vectors with magnetic nanoparticles, the researchers observed that an applied magnetic field triggered a local increase in the rate of cellular uptake of the vectors (with vari... […]
via Bing News