Tiny magnetic particles from air pollution have for the first time been discovered to be lodged in human brains– and researchers think they could be a possible cause of Alzheimer’s disease.
Researchers at Lancaster University found abundant magnetite nanoparticles in the brain tissue from 37 individuals aged three to 92-years-old who lived in Mexico City and Manchester. This strongly magnetic mineral is toxic and has been implicated in the production of reactive oxygen species (free radicals) in the human brain, which are associated with neurodegenerative diseases including Alzheimer’s disease.
Professor Barbara Maher, from Lancaster Environment Centre, and colleagues (from Oxford, Glasgow, Manchester and Mexico City) used spectroscopic analysis to identify the particles as magnetite. Unlike angular magnetite particles that are believed to form naturally within the brain, most of the observed particles were spherical, with diameters up to 150 nm, some with fused surfaces, all characteristic of high-temperature formation – such as from vehicle (particularly diesel) engines or open fires.
The spherical particles are often accompanied by nanoparticles containing other metals, such as platinum, nickel, and cobalt.
Professor Maher said: “The particles we found are strikingly similar to the magnetite nanospheres that are abundant in the airborne pollution found in urban settings, especially next to busy roads, and which are formed by combustion or frictional heating from vehicle engines or brakes.”
Other sources of magnetite nanoparticles include open fires and poorly sealed stoves within homes. Particles smaller than 200 nm are small enough to enter the brain directly through the olfactory nerve after breathing air pollution through the nose.
“Our results indicate that magnetite nanoparticles in the atmosphere can enter the human brain, where they might pose a risk to human health, including conditions such as Alzheimer’s disease,” added Professor Maher.
Leading Alzheimer’s researcher Professor David Allsop, of Lancaster University’s Faculty of Health and Medicine, said: “This finding opens up a whole new avenue for research into a possible environmental risk factor for a range of different brain diseases.”
The Latest on: Magnetite nanoparticles
via Google News
The Latest on: Magnetite nanoparticles
- Modification of existing nitrile latex with magnetite nano particle on December 14, 2018 at 6:12 am
The present invention provides a method to produce black iron oxide nanoparticle slurry having a magnetite structure and homogenously disperse. It can be used as formed or mixed with another medium. […]
- Alzheimer's: Funding boost for nanotechnology research on December 13, 2018 at 11:57 pm
In the lab, the team are using nanoparticles made of iron oxide with special magnetic properties and coated with an antibody to seek out and target the plaques in the brain. The aim is to better diagn... […]
- Modification of nitrile latex with magnetite nanoparticles to prevent glove contamination on December 13, 2018 at 5:24 pm
(Nanowerk News) NBR (nitrile- butadiene rubber) gloves are used extensively in food and pharmaceutical industries when handling products. However, poor elasticity of NBR may cause small pieces of the ... […]
- Insights into magnetotactic bacteria could guide development of biological nanorobots on December 12, 2018 at 2:22 am
Magnetotactic bacteria are a unique aquatic species which use magnetic nanoparticles as an internal compass to navigate The configuration of the magnetic chain in these bacteria has been analyzed usin... […]
- Iranian Scientists Use Nano-Conductors for Smart Treatment of Diabetes on December 12, 2018 at 1:43 am
Superparamagnetic iron oxide nanoparticles (SPION) have been largely considered for numerous applications in biomedicine such as magnetic resonance imaging, hyperthermia, cell tracking ... […]
- Insights into magnetic bacteria may guide research into medical nanorobots on December 11, 2018 at 7:12 am
Magnetic nanoparticles are central to many applications, ranging from biomedical diagnostics to data storage, and even hyperthermia cancer treatments, but the magnetic structures within and in ... […]
- Integrating Nanoparticles into Optoelectronic Semiconductor Devices on December 10, 2018 at 7:17 am
Direct imaging of hybridized eigenmodes in coupled silicon nanoparticles, Optica 3, 93-99 (2016).  M. A. van de Haar et al., Controlling magnetic and electric dipole modes in hollow silicon nanocyl... […]
- Ultrasound-activated nanoparticles provide targeted control of brain activity on December 10, 2018 at 3:04 am
Nanoparticle-mediated ultrasonic drug uncaging can noninvasively ... which is extremely invasive, or use of trans-cranial magnetic or acoustic stimulation of neurones. Such stimulation is imprecise, h... […]
- Micro-fabricated Magnetic Structures for the Future Medicine on December 9, 2018 at 11:35 pm
Sophisticated physical fabrication techniques are bottom-up fabrication, nanoparticle, top-down fabrication, micro-fabrication and magnetization vortex state. These methods allow fabricating a variety ... […]
via Bing News