Led by Dr Jiri Cervenka and PhD candidate Nikolai Dontschuk from the University of Melbourne, the study also included scientists from the Australian Synchrotron and La Trobe University and is published in Nature Communications.
The Australian researchers have shown that graphene- a one-atom thick sheet of hexagonally arranged carbon, shaped like chicken wire – can detect the four nucleobases that make up DNA (cytosine, guanine, adenine and thymine).
A unique combination of the four nucleobases makes up the individual DNA sequence of a gene. Currently, DNA sequencing is a fundamental tool for medical diagnostics, forensic testing and medical and biological research.
The use of graphene to electrically sequence DNA promises to improve the speed, throughput, reliability and accuracy whilst reducing the price compared to current techniques said Nikolai Dontschuk from the University of Melbourne.
“We found that each nucleobase influenced the electronic structure of graphene in a measurably different way,” said Mr Dontschuk.
“When used in conjunction with a nanopore (a tiny hole), a single DNA molecule would pass through the graphene-based electrical sensor – like a single string of beads passing through one section of tiny chicken wire- enabling real-time, high-throughput sequencing of a single DNA molecule.”
The Latest on: Real time DNA sequencing
via Google News
The Latest on: Real time DNA sequencing
- Oxford Nanopore Launches MinIT, Enabling Real Time, Portable DNA Sequencing on March 21, 2019 at 5:00 pm
October 12, 2018 | Oxford Nanopore has announced they are shipping their new MinIT, a rapid analysis and device control accessory for nanopore DNA sequencing, to genomics researchers. MinIT, equipped ... […]
- Application of cell-free DNA sequencing in characterization of bloodborne microbes and the study of microbe-disease interactions on March 14, 2019 at 5:00 pm
Recent reports indicated that cell-free DNA (cfDNA) sequencing using advanced sequencing ... Single-molecule sequencing (SMS) using either SMRT (single-molecule real-time) sequencing or Nanopore ... […]
- Oxford Nanopore Launches Flongle for Rapid, Smaller DNA/RNA Sequencing Tests in Any Environment on March 12, 2019 at 11:09 am
Flongle introduces a new paradigm of smaller, on-demand DNA or RNA sequencing tests ... It uses the same core nanopore sequencing technology as other Oxford Nanopore devices, producing real-time data, ... […]
- DNA Sequencing Market 2019 – Market Size, Analysis, Share, Research, Growth on February 19, 2019 at 8:26 am
Technological drivers such as next generation sequencing (NGS) is the future of sequencing owing to its ability to measures real time nucleotides addition to a DNA molecule. Next generation sequencing ... […]
- DNA sequencing can help fight epidemics—but there are privacy risks on January 14, 2019 at 6:05 am
Some researchers hope it will soon be possible to combine sequencing data collected in this way with ... allowing public health responses to be suggested in real time. There's no doubt these efforts ... […]
- DNA Sequencing Market Foreseen to Witness Fabulous Growth by 2023 Growing with approx. 17.64 % CAGR from 2018 – 2023; Declares MRFR on December 6, 2018 at 3:32 am
DNA Sequencing is a process used for determining the precise nucleotides order in a DNA molecule. DNA sequencing has the ability to measure real-time nucleotides in addition to a DNA molecule; hence, ... […]
- Oxford Nanopore Launches MinIT, a Powerful Analysis Device to Enable Real Time, Portable DNA Sequencing on October 10, 2018 at 3:45 am
OXFORD, England--(BUSINESS WIRE)--MinIT, a rapid analysis and device control accessory for nanopore DNA sequencing, is now arriving with genomics researchers. Scientists will use it to run the MinION ... […]
- Real-Time DNA Sequencing in the Palm of Your Hand on October 9, 2018 at 8:00 pm
In the vast stretches of iron-red soil fields in much of Africa, cassava plays an essential role in the food supply and livelihoods of over 800 million people. Think rice in Asia and wheat in Europe. ... […]
- Oxford Nanopore Launches MinIT, a Powerful Analysis Device to Enable Real Time, Portable DNA Sequencing on October 9, 2018 at 5:00 pm
MinIT, a rapid analysis and device control accessory for nanopore DNA sequencing, is now arriving with genomics researchers. Scientists will use it to run the MinION DNA/RNA sequencer, opening up high ... […]
- Real Time, Portable DNA Sequencing Fights Drug-Resistant TB on May 22, 2018 at 5:00 pm
Scientists in Madagascar have for the first time performed DNA sequencing in-country using novel, portable technology to rapidly identify the bacteria responsible for tuberculosis (TB) and its drug ... […]
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