AIV can be detected based on odor changes in infected birds
New research from the Monell Chemical Senses Center and the U.S. Department of Agriculture (USDA) reveals how diseases can modify animal odors in subtle ways. In a recent study published in the public access journal PLOS ONE, scientists examined how infection with avian influenza (AIV) alters fecal odors in mallards.
Using both behavioral and chemical methods, the findings reveal that AIV can be detected based on odor changes in infected birds.
“The fact that a distinctive fecal odor is emitted from infected ducks suggests that avian influenza infection in mallards may be ‘advertised’ to other members of the population,” notes Bruce Kimball, PhD, a research chemist with the USDA National Wildlife Research Center (NWRC) stationed at the Monell Center. “Whether this chemical communication benefits non-infected birds by warning them to stay away from sick ducks or if it benefits the pathogen by increasing the attractiveness of the infected individual to other birds, is unknown.”
In the study, laboratory mice were trained to discriminate between feces from AIV-infected and non-infected ducks, indicating a change in odor. Chemical analysis then identified the chemical compounds associated with the odor changes as acetoin and 1-octen-3-ol.
The same compounds also have been identified as potential biomarkers for diagnosing gastrointestinal diseases in humans. Kimball and colleagues hypothesize that metabolites resulting from viral infection interact in concert with bacteria in the gastro-intestinal system of ducks to produce “odor signatures” indicating presence of the AI virus.
“Avian influenzas are typically asymptomatic in ducks and waterfowl. Infection in these species can only be diagnosed by directly detecting the virus, requiring capture of birds and collection of swab samples. Our results suggest that rapid and simple detection of influenzas in waterfowl populations may be possible through exploiting this odor change phenomenon,” said Monell behavioral biologist Gary Beauchamp, PhD, also an author on the paper.
Future work will assess whether odor changes can be used for surveillance of AIV in waterfowl. In particular, researchers are interested in whether the odor change is specific to the AIV pathogen or if it is merely a general response to a variety of pathogens normally found in birds. Other studies will explore communicative functions of the AIV odor to gain greater understanding of how odors can shape social behavior in wildlife populations.
The Latest on: Virus Detection by Smells
- Deck the halls, or get decked out: BioWorld’s 12th annual Holiday Gift Guide on November 20, 2018 at 12:45 pm
Although the topic isn’t exactly appetizing, Flu Hunter: Unlocking the secrets of a virus, by Robert Webster ... to find land mines or detect tuberculosis using their extraordinary sense of smell. Cur... […]
- Biologists Decipher a Key Piece of the Odor-Detection Puzzle in Flies, Mosquitoes on February 8, 2018 at 9:16 am
In further research, Ray and his colleagues will continue to explore the odor-detection machinery in mosquitoes, seeking natural chemicals that could be used in products to render mosquitoes insensiti... […]
- Biologists decipher a key piece of the odor-detection puzzle in flies, mosquitoes on February 7, 2018 at 4:00 pm
and Culex that can transmit West Nile virus. Ray said their findings have also led to a more sophisticated understanding of how the odor-detecting machinery processes signals from the complex mixtures ... […]
- Sodium citrate spray could temporarily restore sense of smell on April 4, 2017 at 5:00 pm
A substance commonly used to treat bladder issues could temporarily treat people ... improvement in the ability to smell for patients suffering from anosmia or hyposmia – the loss of smell – in cases ... […]
- What It’s Like To Lose Your Sense Of Taste And Smell on January 2, 2017 at 8:16 am
An estimated three to six per cent of the population suffers from anosmia While it's difficult to lose true taste—the ability to detect sweet ... also be caused by a virus or a head injury that damage... […]
via Google News and Bing News