A lightweight and field-portable device invented at UCLA that conducts kidney tests and transmits data through a smartphone attachment may significantly reduce the need for frequent office visits by people with diabetes and others with chronic kidney ailments.
The smartphone-based device was developed in the research lab of Aydogan Ozcan, a professor of electrical engineering and bioengineering at the UCLA Henry Samueli School of Engineering and Applied Science, and associate director of the California NanoSystems Institute. Weighing about one-third of a pound, the gadget can determine levels of albumin in the patient’s urine and transmit the results within seconds. Albumin is a protein in blood that is a sign of danger when found in urine.
Ozcan’s lab also developed the opto-mechanical phone attachment, disposable test tubes, Android app and software to transmit the data. The research was published this month by the peer-reviewed journal Lab on a Chip.
“Albumin testing is frequently done to assess kidney damage, especially for diabetes patients,” Ozcan said. “This device provides an extremely convenient platform for chronic patients at home or in remote locations where cell phones work.”
Patients at risk for diabetes, kidney disease and other ailments must regularly provide fluid samples — sometimes more than one a day — to monitor their health, which requires visits to labs or health centers.
The new device projects beams of visible light through two small fluorescent tubes attached to the device, one containing a control liquid and the other a urine sample mixed with fluorescent dyes. The smartphone camera captures the fluorescent light after it passes through an additional lens.
An Android application then processes the raw images in less than one second and the device transmits the test results to a database or health care provider. The test, which measures albumin concentration in urine, is accurate to within less than 10 micrograms per milliliter, according to the research, well within accepted clinical standards used in diagnosing conditions such as microalbuminuria, the excretion of albumin in urine.
he time it takes to conduct a test, including preparation of a sample using a small syringe to inject the urine into a fluorescent tube, is about five minutes. Ozcan estimates that the device — for which his lab also has developed an iPhone app — could be produced commercially for $50 to $100 per unit.
The Latest on: Diagnosing disease
Jamestown man's leg pain diagnosed as PVD
on June 17, 2018 at 12:33 pm
But, what if your issue can be fixed? A doctor from Sanford Hospital says your aches and pains might be peripheral vascular disease, also known as PVD. Sixty-six-year-old Calvin Ova loves to go walking outside and doing his job, but a few months ago a ... […]
UCSF researcher, a rising star in study of ALS, now ravaged by disease
on June 17, 2018 at 10:30 am
He hasn’t. Since his diagnosis, Desikan has been an author, often the lead or senior one, of 25 papers in major academic journals on topics such as schizophrenia, Alzheimer’s disease and Parkinson’s disease. As part of his huge ALS study, he and ... […]
Commentary: Five myths about Alzheimer's disease
on June 17, 2018 at 5:04 am
Older adults report that a diagnosis of Alzheimer's disease is the thing they most fear about their future. Alzheimer's is a progressive brain disease characterized by increasing forgetfulness and confusion, eventually resulting in loss of independence and ... […]
Should Ebola or another infectious disease strike Chattanooga, a team of health care professionals is ready [photos]
on June 16, 2018 at 9:03 pm
Dr. Jay Sizemore, an infectious diseases specialist and medical consultant for the ... In the case of a positive diagnosis, patients would be transported from the room to EMS in an individual isolation unit known as the ISO-POD that has its own oxygen ... […]
Local lawmaker proposes a bill to find a cure for Lyme disease
on June 16, 2018 at 8:47 pm
Lyme disease is a bacterial infection that is transmitted by the bite of a deer tick. The disease can be hard to diagnose if you don't see the tick, the initial bite or the bulls eye rash. "Many Drs.will do one test and may not identify when someone ... […]
Tick-Borne Disease Fatal To Cats
on June 16, 2018 at 7:42 pm
It doesn't take long for Bobcat Fever to become fatal, just five to seven days. Dr. Zacharias says right now, they are diagnosing the disease to cats every few days. "Here at this practice we see about 2-3 cases a month, in other areas they see 2-3 or more ... […]
Idaho child diagnosed with plague; only fifth human case in state history
on June 16, 2018 at 3:40 pm
A child in Elmore County, Idaho, is recovering from plague -- in the first human case of the bacterial disease in Idaho since 1992. Central District Health Department epidemiologists say it is not known whether the child was exposed to plague in Idaho or ... […]
With Lyme disease on the rise, why do so many chronic sufferers struggle to convince doctors they're sick?
on June 16, 2018 at 9:46 am
It wasn’t until 2012 that multiple, expensive blood tests from a company called IGeneX confirmed the presence of Lyme disease in her blood, caused by the bite of an infected tick. “I’m one of the rare cases where you have an unequivocal diagnosis. […]
Depression, Anxiety Track Disease Activity in Early Arthritis
on June 16, 2018 at 5:07 am
Rates of anxiety and depression in patients with rheumatoid arthritis correlate with measures of the disease’s activity over the first year following diagnosis, according to new research. Rheumatoid arthritis (RA) is a chronic inflammatory disease that ... […]
WGS helps diagnosis and reduces healthcare costs for neonates in intensive care
on June 16, 2018 at 3:02 am
The researchers are using their current data to investigate how rare genetic diseases present at an earlier stage than they are usually diagnosed in newborns. « Greater numbers of patients will expand our ability to do this, and we hope that our work will ... […]
via Google News and Bing News